Metabolic phenotyping and cardiovascular disease: an overview of evidence from epidemiological settings

Quantifying atherogenic lipoproteins for lipid-lowering strategies: Consensus-based recommendations from EAS and EFLM

(2020) Børge G. Nordestgaard et al.   ATHEROSCLEROSIS

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

(2020) Verena Zuber et al.   Nature Communications

Identifying unknown metabolites using NMR-based metabolic profiling techniques

(2020) Isabel Garcia-Perez et al.   Nature Protocols

Ceramides in Adipose Tissue

(2020) Ying Li et al.   Frontiers in Endocrinology

Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis

(2020) Jowy Yi Hoong Seah et al.   Metabolomics

Assessing the causal association of glycine with risk of cardio-metabolic diseases

(2019) Laura B. L. Wittemans et al.   Nature Communications

Branched-chain amino acids in disease

(2019) Phillip J. White et al.   SCIENCE

The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies

(2019) Bing Yu et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

(2019) Ioanna Tzoulaki et al.   EUROPEAN HEART JOURNAL

Reassessing the Role of Diacylglycerols in Insulin Resistance

(2019) Sisitha U. Jayasinghe et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

(2019) Sifan Chen et al.   Cell Metabolism

A Multi-Cohort Metabolomics Analysis Discloses Sphingomyelin (32:1) Levels to be Inversely Related to Incident Ischemic Stroke

(2019) Lars Lind et al.   Journal of Stroke & Cerebrovascular Diseases

Could Ceramides Become the New Cholesterol?

(2018) Scott A. Summers   Cell Metabolism

Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke

(2018) Michael V. Holmes et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology

(2018) Anna Köttgen et al.   SEMINARS IN NEPHROLOGY

Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

(2018) Adam B. Roberts et al.   NATURE MEDICINE

Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers

(2017) Cavin K Ward-Caviness et al.   HEART

Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted 1H NMR Metabolic Profiling

(2017) Raphaële Castagné et al.   JOURNAL OF PROTEOME RESEARCH

Gut Microbiota Metabolites and Risk of Major Adverse Cardiovascular Disease Events and Death: A Systematic Review and Meta‐Analysis of Prospective Studies

(2017) Yoriko Heianza et al.   Journal of the American Heart Association

Sphingolipids Contribute to Human Atherosclerotic Plaque InflammationHighlights

(2016) Andreas Edsfeldt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Worldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects

(2016) Ioanna Tzoulaki et al.   CIRCULATION

Genetic markers as instrumental variables

(2016) Stephanie von Hinke et al.   JOURNAL OF HEALTH ECONOMICS

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

(2016) Peter Würtz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of 3 Population-Based Cohorts

(2015) P. Wurtz et al.   CIRCULATION

Contributions of risk factors and medical care to cardiovascular mortality trends

(2015) Majid Ezzati et al.   Nature Reviews Cardiology

A metabolomic profile is associated with the risk of incident coronary heart disease

(2014) Anika A.M. Vaarhorst et al.   AMERICAN HEART JOURNAL

Design and Analysis of Metabolomics Studies in Epidemiologic Research: A Primer on -Omic Technologies

(2014) I. Tzoulaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study

(2014) Christin Stegemann et al.   CIRCULATION

Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease

(2014) Andrea Ganna et al.   PLoS Genetics

MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG

(2013) Joram M. Posma et al.   BIOINFORMATICS

American Association of Clinical Endocrinologists' Guidelines for Management of Dyslipidemia and Prevention of Atherosclerosis

(2013) Paul Jellinger et al.   Endocrine Practice

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease

(2012) Svati H. Shah et al.   AMERICAN HEART JOURNAL

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

(2011) Warwick B Dunn et al.   Nature Protocols

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

(2008) Gregory D. Lewis et al.   JOURNAL OF CLINICAL INVESTIGATION