Article
Chemistry, Applied
Zichen Yang, Chaoqun Ma, Jiao Gu, Yamin Wu, Chun Zhu, Lei Li, Hui Gao, Wenzhi Yin, Zirui Wang, Guoqing Chen
Summary: By utilizing COF materials as ligands, we have successfully reduced the interference from milk adulterants and developed carboxyl-functionalized Ag-COF-COOH materials as SERS substrates for the detection of melamine. This method demonstrates high sensitivity and reliability, with a detection limit of 0.68 μg/L in liquid milk, and shows great potential for applications in the food surveillance industry.
Article
Physics, Applied
Malik H. Mahmood, Ali Jaafar, Laszlo Himics, Laszlo Peter, Istvan Rigo, Shereen Zangana, Attila Bonyar, Miklos Veres
Summary: A novel platform for surface-enhanced Raman scattering (SERS) was developed by decorating diethylene glycol dimethacrylate microparticles with gold nanoparticles, resulting in significant enhancement of the Raman signal. Near-infrared excitation at 532, 633, and 785 nm exhibited the highest enhancement on the substrate, which also showed excellent temporal stability and spatial uniformity. The practical application potential of this SERS substrate was demonstrated by detecting DNA sequences.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Spectroscopy
Tong Zhang, Shunhua Zhu, Jingjing Wang, Zhiying Liu, Mingxin Wang, Shibao Li, Qingli Huang
Summary: Fabricating sensitive, stable and low-cost nanomaterials for glucose detection is crucial for disease diagnosis and monitoring. In this study, a nanocomposite (polypyrrole bridging GO@Au@MnO2) was developed as a novel surface-enhanced Raman scattering (SERS) nanoprobe for quantitative glucose detection in trace serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Nanoscience & Nanotechnology
D. Jin, Y. Lee, C. Lee, M. H. Kim
Summary: This study successfully deposited 3-dimensional silver microstructures on a glassy carbon surface using programmed electrodeposition. The morphology-controlled silver deposits showed enhanced Raman signals and exhibited good reproducibility.
MATERIALS TODAY NANO
(2023)
Article
Chemistry, Analytical
Zichen Yang, Guoqing Chen, Chaoqun Ma, Jiao Gu, Chun Zhu, Lei Li, Hui Gao
Summary: In this study, Surface-Enhanced Raman Scattering (SERS) technology was applied to the detection of quinolone antibiotics, and a combination of magnetic COF-based SERS substrate and machine learning algorithms was used for their classification and quantification. The classification accuracy of the spectral dataset reached 100%. This provides a new method for the detection of antibiotics in dairy products.
Article
Chemistry, Analytical
Di Liu, Huimin Gao, Wenji Jiang, Su Yan, Hao Liu, Junjie Chen, Sisi Wen, Wei Zhang, Xu Wang, Bing Zhao, Wei Song
Summary: In this study, three-dimensional Ag aerogel-supported Hg single-atom catalysts were used as an efficient SERS substrate for monitoring enhanced oxidase-like reactions. The effect of Hg2+ concentrations on the SERS properties of 3D Hg/Ag aerogel networks was investigated, and an optimized addition of Hg2+ resulted in specific enhancement. The formation of Ag-supported Hg SACs was confirmed using HAADF-STEM imaging and XPS measurement, and the oxidase-like catalytic mechanism of Hg/Ag SACs was revealed using DFT. This research provides a mild synthetic strategy for fabricating Ag aerogel-supported Hg single atoms with promising prospects in various catalytic fields.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
W. Cheuquepan, S. Hernandez, M. Perez-Estebanez, L. Romay, A. Heras, A. Colina
Summary: Electrochemistry can be used to generate SERS substrates, utilizing the plasmonic properties of nanos-tructures and the chemical mechanism, with time-resolved Raman spectroelectrochemistry providing valuable information. Comparing Au and Ag metals for folic acid detection in drugs, it was found that Ag SERS substrates outperformed Au SERS substrates in complex samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
Zichen Yang, Chaoqun Ma, Jiao Gu, Yamin Wu, Chun Zhu, Lei Li, Hui Gao, Wenzhi Yin, Zirui Wang, Ye Zhang, Yunpeng Shang, Chengwei Wang, Guoqing Chen
Summary: A surface-enhanced Raman scattering (SERS) method using Ag-COF material as substrate has been developed for the detection of benzoic acid in milk, showing high sensitivity and reliability. This method provides a new approach for the detection of benzoic acid in dairy products.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yan Zhai, Tong Xuan, Yiping Wu, Xiaoyu Guo, Ye Ying, Ying Wen, Haifeng Yang
Summary: The newly developed ITO-Au@Ag-5@ZIF-8 (1.5 h) chip enables rapid and stable detection of carbendazim in seawater with high sensitivity and linearity. By improving adsorption and accumulation, the precise detection of target molecules is achieved.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Yazhou Qin, Yuanzhao Wu, Binjie Wang, Jiye Wang, Weixun Yao
Summary: A simple method was developed to grow island-shaped gold nanoparticles on the surface of silver nanowires, creating Ag@Au NWs with combined advantages. By optimizing the density of gold nanoparticles on the Ag NWs surface, excellent uniformity and sensitivity of the SERS substrate were achieved. Furthermore, highly sensitive SERS detection of tropane alkaloids was realized by analyzing characteristic peaks in the obtained SERS spectra.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Xiaoxiao Zhou, Shouhui Chen, Yi Pan, Yuanfeng Wang, Naifeng Xu, Yanwen Xue, Xinlin Wei, Ying Lu
Summary: In order to improve the detection performance of surface-enhanced Raman scattering (SERS), a low-cost Au@Ag nanorods (Au@Ag NRs) substrate with a good SERS enhancement effect was developed and applied to the detection of malachite green (MG) in aquaculture water and crayfish. The developed Au@Ag NRs sensor showed a good signal enhancement effect and achieved a detection limit of 1.58 x 10(-9) M for MG in crayfish. This new tool provided stable SERS signal, uniform size and low cost for SERS signal enhancement and highly sensitive SERS detection method development.
Article
Chemistry, Physical
Yuenan Pan, Qi Chu, Shuang Guo, Sila Jin, Eungyeong Park, Yeonju Park, Yantao Sun, Lei Chen, Young Mee Jung
Summary: The purpose of this study is to investigate the charge transfer process and SERS enhancement mechanism in the Ag/MBA/PAN system with varying thicknesses of PAN. The results show that increasing the PAN thickness leads to higher frequency and intensity of the characteristic MBA band, as well as increased intensity of the b2 mode. The degree of CT also increases with increasing PAN thickness, due to the excited SPR from Ag. The electromagnetic enhancement mechanism at the PAN/Ag interface generates hot electrons and facilitates electron transfer in the CT process.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Sen Li, Defu He, Shuning Li, Ruipeng Chen, Yuan Peng, Shuang Li, Dianpeng Han, Yu Wang, Kang Qin, Shuyue Ren, Ping Chen, Zhixian Gao
Summary: In this study, a novel aptamer sensor based on magnetic separation and surface-enhanced Raman scattering (SERS) was proposed for the sensitive and specific detection of trace BPA. The sensor showed high sensitivity and specificity through the pairing of the BPA aptamer and DNA. The proposed aptasensor is a promising biosensing platform for BPA detection.
Article
Chemistry, Physical
Xueyan Bian, Jiangtao Xu, Jing Yang, Ka-lam Chiu, Shouxiang Jiang
Summary: In this study, silver (Ag) nanoparticles were deposited onto polyester fabric using a magnetron sputtering system. By controlling the argon flow rate and sputtering time, Ag particles of different sizes on the polyester substrate were produced, resulting in different SERS performances. The AP-200 SERS substrate exhibited high sensitivity, reproducibility, stability, and good reusability, with a limit of detection of 1 ppm for R6G collected from an irregular surface. The finite-difference time-domain (FDTD) method was utilized to simulate the formation of hotspots between two Ag nanoparticles and explain the phenomenon of signal enhancement.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Myoung Gyu Kim, Miyeon Jue, Kwan Hee Lee, Eun Yeong Lee, Yeonjeong Roh, Minju Lee, Hyo Joo Lee, Sanghwa Lee, Huifang Liu, Bonhan Koo, Yoon Ok Jang, Eui Yeon Kim, Qiao Zhen, Sung-Han Kim, Jun Ki Kim, Yong Shin
Summary: The study introduces a deep learning assisted ZnO-Au-SERS-based direct amplification (ZADA) system for rapid, sensitive molecular diagnostics. The system can amplify target nucleic acids directly on the SERS surface, eliminating the need for post-amplification hybridization and Raman reporters. Clinical validation with COVID-19 samples yielded high sensitivity and specificity. The integration of a deep learning program further enhanced sensitivity and specificity to 100%.
Article
Chemistry, Physical
Liping Wang, Wenqiong Su, Khan Zara Ahmad, Xin Wang, Ting Zhang, Youyi Yu, Edward Kai-Hua Chow, Dean Ho, Xianting Ding
Summary: This study evaluated the safety of nanodiamonds (ND) as a drug-delivery platform in Naive Beagle dogs, showing that the ND drug delivery platform significantly reduces doxorubicin (DOX) toxicity in the Naive Beagle dog model.
Article
Chemistry, Analytical
Jing Su, Shixing Chen, Yanzhi Dou, Zhihan Zhao, Xiaolong Jia, Xianting Ding, Shiping Song
Summary: A sensitive and portable electrochemical biosensor in combination with smartphones was developed for quantitative analysis of exosomes. The biosensor could detect extremely low concentrations of exosomes in microliter-level serum and cell culture supernatant. It also showed great potential for early diagnosis of prostate disease and monitoring of exosome secretion during drug therapy.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Lulu Zhang, Xiao Liu, Xiaoxiang Chen, Antony R. Warden, Youyi Yu, Baozhen Huang, Xianting Ding
Summary: This study developed a method called SCANCell to quantify the direct association network of cell clusters and applied it to a systemic lupus erythematosus cohort. The results showed that SCANCell can reveal inter-cluster interactions and provide insights into disease pathogenesis and therapeutic strategies.
Article
Chemistry, Applied
Yixia Yang, Behafarid Ghalandari, Liyun Lin, Xiao Sang, Wenqiong Su, Adeleh Divsalar, Xianting Ding
Summary: An ultrasensitive detection method for glyphosate using a Cu2+-modulated DNA-AgNCs sensor was developed, demonstrating a combination of static and dynamic quenching modes with Cu2+-triggered fluorescence quenching. The sensor showed high linearity for glyphosate analysis in the range of 15-100 μg/L and a low detection limit down to 5 μg/L, making it promising for pesticide residues detection in real samples.
Article
Biochemical Research Methods
Roozbeh Abedini-Nassab, Xianting Ding, Haiyang Xie
Summary: The use of magnetic micro- and nanoparticles in medicine and biology is expanding, with one important example being the transport of these particles in lab-on-a-chip systems. This study introduces a novel magnetometer using magnetic micro-disks to evaluate the magnetic susceptibility of numerous individual particles simultaneously. The method has various crucial applications, including magnetic characterization of beads and living cells, determining magnetization rate of cells, evaluating degradation rate of nanoparticles in cells, detecting target cells in samples, and separating particles based on size and magnetic susceptibility.
Article
Chemistry, Multidisciplinary
Yuqing Ke, Behafarid Ghalandari, Shiyi Huang, Sijie Li, Chengjie Huang, Xiao Zhi, Daxiang Cui, Xianting Ding
Summary: In this study, we propose a strategy to enhance the specificity of the Cas12a system by using 2'-O-methyl modified guide RNA (gRNA), and we validate the effectiveness of this strategy through experiments. Our results show that the 2'-OMe modified gRNAs can significantly improve the specificity of Cas12a in discriminating single-base mutations, and molecular docking simulations reveal the mechanism of this enhancement.
Article
Biochemistry & Molecular Biology
Yimin Zheng, Yitian Chen, Xianting Ding, Koon Ho Wong, Edwin Cheung
Summary: Spatial omics is an approach that integrates spatial knowledge with transcript or protein expression information to explore tissue microenvironment and cellular networks. However, there is a lack of databases for users to access and analyze spatial omics data. To address this limitation, Aquila, a comprehensive platform for managing and analyzing spatial omics data, has been developed. Aquila contains 107 datasets from 30 diseases, covering studies using different technologies.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Chunhui Zhai, Jiang Long, Jie He, Yan Zheng, Boqian Wang, Jiaying Xu, Yuting Yang, Lai Jiang, Hui Yu, Xianting Ding
Summary: This study presents a kinetic assay called DISEP, which utilizes surface plasmon resonance microscopy (SPRM) to accurately identify tumor-derived EVs (tEVs) and profile their surface protein expression in clinical plasma. DISEP shows high sensitivity and specificity in detecting tEVs, and it has been successfully used to discriminate between pancreatic cancer patients and healthy donors with a panel of biomarker signatures.
Article
Chemistry, Analytical
Yiyang Li, Boqian Wang, Zara Ahmad Khan, Jie He, Edwin Cheung, Wenqiong Su, Aiting Wang, Hui Jiang, Lai Jiang, Xianting Ding
Summary: This study introduces a method of mass cytometry profiling for analyzing samples with limited or rare cell subsets using a platinum-chimeric carrier cell strategy. The results demonstrate the effectiveness of this method in preserving rare target cells and performing comprehensive single-cell subtype classification analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Li Xu, Haiyang Xie, Boqian Wang, Zijian Zhu, Hui Jiang, Xiaoqian Duan, Shuxin Deng, Jiasu Xu, Lai Jiang, Xianting Ding
Summary: Single-cellwestern blotting (scWB) is a common method for high-resolution protein analysis on low-abundance cell samples. However, antibody stripping during repeated staining leads to signal loss, preventing multiplex protein detection. In this study, we introduce Fluorescent-quenching Aptamer-based Single-cell Western Blotting (FAS-WB) for multiplex protein detection at single-cell resolution. FAS-WB allows rapid penetration, diffusion, and elution of aptamer probes, while avoiding signal loss through the use of fluorophore-tagged aptamers coordinated with quenching strands.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Shuang Zhang, Behafarid Ghalandari, Aiting Wang, Sijie Li, Youming Chen, Qingwen Wang, Lai Jiang, Xianting Ding
Summary: Mass spectrometry has become a mainstream technique for label-free proteomics, but the proteomic coverage for trace samples is limited by adsorption loss during repeated elution. In this study, superparamagnetic composite nanoparticles functionalized with molecular glues were used to enrich proteins in trace human biofluid, and a streamlined workflow method was proposed to achieve unbiased protein capture, digestion, and elution. This method greatly simplified sample preparation steps, minimized adsorption loss, and improved protein coverage for label-free proteomics with trace samples.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biophysics
Jing Su, Shasha Song, Yanzhi Dou, Xiaolong Jia, Shiping Song, Xianting Ding
Summary: Methylation of cancer related genes' promoter region is crucial in cancer occurrence and development, with high potential for early diagnosis. Current quantification methods are time-consuming and expensive. We developed a ultrasensitive MS-ELONA method to detect and quantify DNA methylation level, with the ability to detect as little as 2 pg of methylated DNA in excess unmethylated genes, and differentiate prostate cancer from BPH and control samples. Our research demonstrates a simple and inexpensive method to quantify methylation levels of specific genes, with potential for clinical applications.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Oncology
Zijian Zhu, Lai Jiang, Xianting Ding
Summary: This review discusses the heterogeneity of breast cancer and strategies to understand it using multi-omics profiling methods. It highlights the importance of integrating genomics, transcriptomics, and proteomics to fully unravel the disease's complexity. The use of single-cell analysis and multi-omics approaches holds great promise for advancing breast cancer research and management in the future.
Article
Chemistry, Multidisciplinary
Yanzhi Dou, ZiYue Huang, Tie Li, Nokuzola Maboyi, Xianting Ding, Shiping Song, Jing Su
Summary: We have developed a rapid and accurate biosensor capable of detecting SARS-CoV-2 and distinguishing its mutations. Utilizing a DNA framework-modified ordered interface and a dual signal amplification strategy, our biosensor has a detection limit as low as 10 fM. It has shown excellent performance on pseudo virus and SARS-CoV-2 RNA standard materials, indicating its potential application in disease diagnosis and spread when combined with a homemade smartphone.
CHEMICAL COMMUNICATIONS
(2023)
Article
Cell Biology
Chunhui Zhai, Feng Xie, Jiaying Xu, Yuting Yang, Weiqiang Zheng, Haiyan Hu, Xianting Ding, Hui Yu
Summary: This study investigates the correlation between membrane protein expression level, binding kinetics, and sizes of extracellular vesicles and particles (EVPs) for cancer detection. The results show that by grouping EVPs into subpopulations based on size and analyzing the correlation between membrane proteins and sizes, the overall accuracy of cancer classification can be improved. This work highlights the significance of size-dependent subtyping of EVPs for clinical cancer diagnosis.
JOURNAL OF EXTRACELLULAR VESICLES
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.