期刊
FERTILITY AND STERILITY
卷 115, 期 3, 页码 761-770出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2020.09.006
关键词
Ultrasonography; ovary; antral follicle; diagnostic imaging; reproducibility of results
资金
- Canadian Institutes of Health Research [146182]
- Cornell University
This study found variability in follicle number per ovary assessments across different ultrasonographic methods, with 2D-RT potentially misclassifying PCOM, while 2D-RT with Grid and MPV-RT could be clinically feasible alternatives for obtaining FNPO and classifying PCOM. Efforts to reduce variation in FNPO will clarify the relevance of PCOM in women's health.
Objectives: To determine the level of agreement across assessments of follicle number per ovary (FNPO) and classifying of polycystic ovarian morphology (PCOM; FNPO >= 25) with the use of various real-time (RT) and off-line two-dimensional (2D) and three-dimensional (3D) ultrasonographic methods. Design: Method comparison study. Setting: University-based clinical research unit. Patient(s): Sixteen women with and without PCOM. Intervention: Thirty-two ovaries were analyzed with the use of eight ultrasonographic methods: 2D-Grid (reference method), 2D-RT, 2D-RT with Grid, multiplanar view (MPV), MPV-RT, tomographic ultrasound imaging (TUI), TUI-RT, and semiautomated volume calculation (SonoAVC). Main Outcome Measure(s): FNPO, PCOM status, and time to obtain FNPO. Clinical feasibility, defined as the time taken to obtain FNPO, also was evaluated. Result(s): 2D-RT overestimated FNPO versus 2D-Grid (3 +/- 9 follicles) owing to overcounting in non-PCOM ovaries (6 +/- 6 follicles). However, systematic bias was not detected when a grid overlay was incorporated (2D-RT with Grid). SonoAVC underestimated FNPO (-3 +/- 5 follicles), particularly in PCOM ovaries (-4.1 +/- 5.0 follicles). No bias in FNPO was detected between MPV, TUI, or TUI-RT versus 2D-Grid. 2D-RT significantly misclassified ovaries as PCOM. All methods except MPV took less time to complete FNPO assessments compared with 2D-Grid. Conclusion(s): Variability in FNPO across ultrasonographic methods limits their interchangeable use, particularly when a precise metric is needed. 2D-RT may be problematic owing to its propensity to misclassify PCOM. 2D-RT with Grid and MPV-RT could represent clinically feasible alternatives to obtain FNPO and classify PCOM. Efforts to reduce variation in FNPO will clarify the relevance of PCOM in women's health. (C) 2020 by American Society for Reproductive Medicine.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据