Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

(2020) Dalya Ataca et al.   Nature Communications

Potential association of LOXL1 with peritoneal dissemination in gastric cancer possibly via promotion of EMT

(2020) Qingjiang Hu et al.   PLoS One

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

Exploring Collagen Parameters in Pure Special Types of Invasive Breast Cancer

(2019) Rodrigo de Andrade Natal et al.   Scientific Reports

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin

(2019) Koen Schipper et al.   Nature Communications

The challenges of modeling hormone receptor-positive breast cancer in mice

(2018) Berna C Özdemir et al.   ENDOCRINE-RELATED CANCER

Integrated molecular analysis of Tamoxifen-resistant invasive lobular breast cancer cells identifies MAPK and GRM/mGluR signaling as therapeutic vulnerabilities

(2018) Hillary Stires et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

(2018) Ilirjana Bajrami et al.   Cancer Discovery

E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function

(2018) Tanis D. Godwin et al.   Gastric Cancer

Relationships between circulating branched chain amino acid concentrations and risk of adverse cardiovascular events in patients with STEMI treated with PCI

(2018) Xiaoyu Du et al.   Scientific Reports

Single sample scoring of molecular phenotypes

(2018) Momeneh Foroutan et al.   BMC BIOINFORMATICS

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

(2018) Maryse Fiche et al.   JOURNAL OF PATHOLOGY

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

(2018) Stéphanie Cagnet et al.   Nature Communications

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

(2018) Yeji An et al.   Cell Reports

The Reactome Pathway Knowledgebase

(2017) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

Comprehensive analysis of normal adjacent to tumor transcriptomes

(2017) Dvir Aran et al.   Nature Communications

Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

(2017) HaoRan Tang et al.   Nature Communications

Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo

(2017) Robert D. Bruno et al.   Scientific Reports

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

(2016) George Sflomos et al.   CANCER CELL

Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer

(2016) Philip C. Trackman   EXPERT OPINION ON THERAPEUTIC TARGETS

Genomic Characterization of Primary Invasive Lobular Breast Cancer

(2016) Christine Desmedt et al.   JOURNAL OF CLINICAL ONCOLOGY

p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice

(2016) Milou Tenhagen et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

The mammary ducts create a favourable microenvironment for xenografting of luminal and molecular apocrine breast tumours

(2016) Elodie Richard et al.   JOURNAL OF PATHOLOGY

Lobular breast cancer: Clinical, molecular and morphological characteristics

(2016) Matthias Christgen et al.   PATHOLOGY RESEARCH AND PRACTICE

PTEN Loss in E-Cadherin-Deficient Mouse Mammary Epithelial Cells Rescues Apoptosis and Results in Development of Classical Invasive Lobular Carcinoma

(2016) Mirjam C. Boelens et al.   Cell Reports

Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice

(2015) Loai Alsofi et al.   CALCIFIED TISSUE INTERNATIONAL

Abstract S2-06: Survival advantage of anastrozol compared to tamoxifen for lobular breast cancer in the ABCSG-8 study

(2015) Michael Knauer et al.   CANCER RESEARCH

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

(2015) Giovanni Ciriello et al.   CELL

Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial

(2015) Otto Metzger Filho et al.   JOURNAL OF CLINICAL ONCOLOGY

Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells

(2015) B. J. Telford et al.   MOLECULAR CANCER THERAPEUTICS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response

(2014) M. J. Sikora et al.   CANCER RESEARCH

Invasive lobular breast cancer and its variants: How special are they for systemic therapy decisions?

(2014) Séverine Guiu et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs

(2014) P. J. Balwierz et al.   GENOME RESEARCH

Multifocal epithelial tumors and field cancerization: stroma as a primary determinant

(2014) G. Paolo Dotto   JOURNAL OF CLINICAL INVESTIGATION

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells Is Primarily Due To Isoform ALDH1A3 and Its Expression Is Predictive of Metastasis

(2010) Paola Marcato et al.   STEM CELLS

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type

(2009) Britta Weigelt et al.   JOURNAL OF PATHOLOGY

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERRγ Mediates Tamoxifen Resistance in Novel Models of Invasive Lobular Breast Cancer

(2008) Rebecca B. Riggins et al.   CANCER RESEARCH