The many bits of positional information

Optimal Decoding of Cellular Identities in a Genetic Network

(2019) Mariela D. Petkova et al.   CELL

Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells

(2019) Idse Heemskerk et al.   eLife

Estimating information in time-varying signals

(2019) Sarah Anhala Cepeda-Humerez et al.   PLoS Computational Biology

Unravelling cellular relationships during development and regeneration using genetic lineage tracing

(2019) Chloé S. Baron et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wolpert's French Flag: what's the problem?

(2019) James Sharpe   DEVELOPMENT

Distributed and dynamic intracellular organization of extracellular information

(2018) Alejandro A. Granados et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting

(2018) Benjamin Zoller et al.   CELL

Decoding of position in the developing neural tube from antiparallel morphogen gradients

(2017) Marcin Zagorski et al.   SCIENCE

Synthesizing developmental trajectories

(2017) Paul Villoutreix et al.   PLoS Computational Biology

Using goal-driven deep learning models to understand sensory cortex

(2016) Daniel L K Yamins et al.   NATURE NEUROSCIENCE

Limits to the precision of gradient sensing with spatial communication and temporal integration

(2016) Andrew Mugler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Information Processing in Living Systems

(2016) Gašper Tkačik et al.   Annual Review of Condensed Matter Physics

Precision of Readout at the hunchback Gene: Analyzing Short Transcription Time Traces in Living Fly Embryos

(2016) Jonathan Desponds et al.   PLoS Computational Biology

Beyond the French Flag Model: Exploiting Spatial and Gene Regulatory Interactions for Positional Information

(2016) Patrick Hillenbrand et al.   PLoS One

Positional information and reaction-diffusion: two big ideas in developmental biology combine

(2015) J. B. A. Green et al.   DEVELOPMENT

Morphogen rules: design principles of gradient-mediated embryo patterning

(2015) J. Briscoe et al.   DEVELOPMENT

Optimizing information flow in small genetic networks. IV. Spatial coupling

(2015) Thomas R. Sokolowski et al.   PHYSICAL REVIEW E

Deep Neural Networks: A New Framework for Modeling Biological Vision and Brain Information Processing

(2015) Nikolaus Kriegeskorte   Annual Review of Vision Science

Maternal Origins of Developmental Reproducibility

(2014) Mariela D. Petkova et al.   CURRENT BIOLOGY

Environmental sensing, information transfer, and cellular decision-making

(2014) Clive G Bowsher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Positional Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical Framework

(2014) G. Tka ik et al.   GENETICS

Noise in biology

(2014) Lev S Tsimring   REPORTS ON PROGRESS IN PHYSICS

The embryo as a laboratory: quantifying transcription in Drosophila

(2014) Thomas Gregor et al.   TRENDS IN GENETICS

Drosophila Embryogenesis Scales Uniformly across Temperature in Developmentally Diverse Species

(2014) Steven G. Kuntz et al.   PLoS Genetics

Precise Developmental Gene Expression Arises from Globally Stochastic Transcriptional Activity

(2013) Shawn C. Little et al.   CELL

Adaptation of the length scale and amplitude of the Bicoid gradient profile to achieve robust patterning in abnormally large Drosophila melanogaster embryos

(2013) D. Cheung et al.   DEVELOPMENT

Accurate measurements of dynamics and reproducibility in small genetic networks

(2013) J. O. Dubuis et al.   Molecular Systems Biology

Positional information, in bits

(2013) J. O. Dubuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Temporal dynamics, spatial range, and transcriptional interpretation of the Dorsal morphogen gradient

(2012) Christine A Rushlow et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Encoding and decoding of positional information in morphogen-dependent patterning

(2012) Ken-ichi Hironaka et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock

(2012) A. C. Oates et al.   DEVELOPMENT

Dorsal-Ventral Gene Expression in the Drosophila Embryo Reflects the Dynamics and Precision of the Dorsal Nuclear Gradient

(2012) Gregory T. Reeves et al.   DEVELOPMENTAL CELL

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

How to build a robust intracellular concentration gradient

(2012) Martin Howard   TRENDS IN CELL BIOLOGY

Mutual Repression Enhances the Steepness and Precision of Gene Expression Boundaries

(2012) Thomas R. Sokolowski et al.   PLoS Computational Biology

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

Coding Design of Positional Information for Robust Morphogenesis

(2011) Yoshihiro Morishita et al.   BIOPHYSICAL JOURNAL

Information transmission in genetic regulatory networks: a review

(2011) Gašper Tkačik et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Multiplexing Biochemical Signals

(2011) Wiet de Ronde et al.   PHYSICAL REVIEW LETTERS

A Biological Solution to a Fundamental Distributed Computing Problem

(2011) Y. Afek et al.   SCIENCE

Shaping a Morphogen Gradient for Positional Precision

(2010) Feng He et al.   BIOPHYSICAL JOURNAL

ARTIFICIAL SELECTION ON EGG SIZE PERTURBS EARLY PATTERN FORMATION IN DROSOPHILA MELANOGASTER

(2010) Cecelia M. Miles et al.   EVOLUTION

Information-Optimal Transcriptional Response to Oscillatory Driving

(2010) Andrew Mugler et al.   PHYSICAL REVIEW LETTERS

Physical Limits on Cellular Sensing of Spatial Gradients

(2010) Bo Hu et al.   PHYSICAL REVIEW LETTERS

Accuracy of positional information provided by multiple morphogen gradients with correlated noise

(2009) Yoshihiro Morishita et al.   PHYSICAL REVIEW E

Optimizing information flow in small genetic networks

(2009) Gašper Tkačik et al.   PHYSICAL REVIEW E

Mutual Information between Input and Output Trajectories of Biochemical Networks

(2009) Filipe Tostevin et al.   PHYSICAL REVIEW LETTERS

Role of Spatial Averaging in the Precision of Gene Expression Patterns

(2009) Thorsten Erdmann et al.   PHYSICAL REVIEW LETTERS

Regulative feedback in pattern formation: towards a general relativistic theory of positional information

(2008) J. Jaeger et al.   DEVELOPMENT

Precision of the Dpp gradient

(2008) T. Bollenbach et al.   DEVELOPMENT

Information capacity of genetic regulatory elements

(2008) Gašper Tkačik et al.   PHYSICAL REVIEW E

The Role of Input Noise in Transcriptional Regulation

(2008) Gašper Tkačik et al.   PLoS One

Information flow and optimization in transcriptional regulation

(2008) G. Tkacik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA