Article
Cardiac & Cardiovascular Systems
Jennifer S. Lawton, Jacqueline E. Tamis-Holland, Sripal Bangalore, Eric R. Bates, Theresa M. Beckie, James M. Bischoff, John A. Bittl, Mauricio G. Cohen, J. Michael DiMaio, Creighton W. Don, Stephen E. Fremes, Mario F. Gaudino, Zachary D. Goldberger, Michael C. Grant, Jang B. Jaswal, Paul A. Kurlansky, Roxana Mehran, Thomas S. Jr Jr Metkus, Lorraine C. Nnacheta, Sunil Rao, Frank W. Sellke, Garima Sharma, Celina M. Yong, Brittany A. Zwischenberger
Summary: The executive summary of the American College of Cardiology/American Heart Association/Society for Cardiovascular Angiography and Interventions coronary artery revascularization guideline provides a patient-centric approach to guide clinicians in the treatment of patients with significant coronary artery disease. This summary includes the top 10 take-home messages from the full guideline, along with recommendations, tables, and figures.
Review
Medicine, General & Internal
Amir Qaseem, Cristin A. Mount, Karen Campos, Robert M. McLean, Samantha Tierney, J. Thomas Cross, Nick Fitterman
Summary: Primary osteoporosis is a common health issue characterized by decreasing bone mass and increasing fracture risk. Performance measures have been developed to assess and improve the effectiveness of screening, diagnosis, and treatment. However, the reliability and validity of these measures have been questioned. This paper reviews current performance measures on osteoporosis and provides guidance for selecting appropriate measures.
ANNALS OF INTERNAL MEDICINE
(2023)
Article
Medicine, General & Internal
Mads M. Helsted, Laerke S. Gasbjerg, Tina Vilsboll, Casper K. Nielsen, Julie L. Forman, Mikkel B. Christensen, Filip K. Knop
Summary: Due to the reduced insulinotropic effect of GIP in type 2 diabetes, GIP has not been considered as a therapeutic option. However, tirzepatide, a dual incretin receptor agonist, has shown more significant glucose and weight-lowering effects compared to GLP-1 receptor agonist therapy. The role of GIP receptor activation in the efficacy of tirzepatide remains unknown. This study aims to evaluate the glucose-lowering effect of exogenous GIP in patients with type 2 diabetes under pharmacological GLP-1 receptor activation.
Review
Cardiac & Cardiovascular Systems
Paul A. Heidenreich, Biykem Bozkurt, David Aguilar, Larry A. Allen, Joni J. Byun, Monica M. Colvin, Anita Deswal, Mark H. Drazner, Shannon M. Dunlay, Linda R. Evers, James C. Fang, Savitri E. Fedson, Gregg C. Fonarow, Salim S. Hayek, Adrian F. Hernandez, Prateeti Khazanie, Michelle M. Kittleson, Christopher S. Lee, Mark S. Link, Carmelo A. Milano, Lorraine C. Nnacheta, Alexander T. Sandhu, Lynne Warner Stevenson, Orly Vardeny, Amanda R. Vest, Clyde W. Yancy
Summary: The 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure is an updated version of the 2013 and 2017 guidelines, aiming to provide patient-centric recommendations for the prevention, diagnosis, and management of heart failure. This guideline is based on contemporary evidence and presents an evidence-based approach to improve quality of care and align with patients' interests.
Article
Endocrinology & Metabolism
Bernard Cortet, Anne-Marie Schott, Gaelle Desamericq, Jean-Vannak Chauny, Pascale Samama, Corinne Emery, Francis Fagnani
Summary: The trends in pharmacological management of postmenopausal osteoporosis in France from 2007 to 2016 showed marked changes, with a slight increase followed by a rapid decrease in the rates of women receiving any anti-osteoporosis medications. The use of calcium/vitamin D as the only prevention and exclusive intervention for postmenopausal osteoporosis significantly increased. Patients initiating anti-osteoporosis medications showed a shift towards higher risk individuals with more severe chronic comorbidities, history of fractures, and high-dose steroid use over the 10-year period.
Article
Medical Laboratory Technology
David A. Novis, Suzanne N. Coulter, Barbara Blond, Peter Perrotta
Summary: This study reports on the normative rates of laboratory technical staffing ratios and analyzes the factors associated with these ratios. The results show significant variations in staffing ratios between different institutions and laboratory departments, with testing volume and practice characteristics being associated with staffing ratios.
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2022)
Review
Pathology
Soo-Ryum Yang, Mary B. Beasley, Andrew Churg, Thomas V. Colby, Evans R. Fernandez Perez, David Lynch, Nestor L. Muller, William D. Travis
Summary: Assessment of lung biopsies for the diagnosis of hypersensitivity pneumonitis (HP) is challenging. The American College of Chest Physicians has published guidelines for the diagnosis of HP to address these challenges. This review explores the multidisciplinary diagnostic evaluation of HP, highlighting histologic features and the correlation of lung biopsies with computed tomography findings.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
(2022)
Article
Endocrinology & Metabolism
Kailyn E. Sitter, Denise H. Wong, Rendelle E. Bolton, Varsha G. Vimalananda
Summary: In the absence of guidelines, endocrinologists' judgments of the clinical appropriateness for telehealth vary widely, which may lead to unintended and clinically unwarranted variation in the use of telehealth, compromising the quality of care.
JOURNAL OF THE ENDOCRINE SOCIETY
(2022)
Article
Cardiac & Cardiovascular Systems
Catherine M. Otto, Rick A. Nishimura, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Federico Gentile, Hani Jneid, Eric Krieger, Michael Mack, Christopher McLeod, Patrick T. O'Gara, Vera H. Rigolin, Thoralf M. Sundt, Annemarie Thompson, Christopher Toly
Summary: This executive summary of the valvular heart disease guideline provides recommendations and supporting documentation for clinicians to diagnose and manage valvular heart disease. It includes updated recommendations with newer options for diagnosis and treatment, focusing on diagnostic work-up, the timing and choice of surgical and catheter interventions, and recommendations for medical therapy.
Article
Gastroenterology & Hepatology
Lin Chang, William D. Chey, Aamer Imdad, Christopher V. Almario, Adil E. Bharucha, Susan Diem, Katarina B. Greer, Brian Hanson, Lucinda A. Harris, Cynthia Ko, M. Hassan Murad, Amit Patel, Eric D. Shah, Anthony J. Lembo, Shahnaz Sultan
Summary: This article provides evidence-based practice recommendations for the pharmacological treatment of chronic idiopathic constipation (CIC), with 10 recommendations agreed upon by a multidisciplinary guideline panel. Some medications, such as polyethylene glycol and linaclotide, are strongly recommended for CIC treatment in adults, while others, such as fiber, are conditionally recommended.
Article
Gastroenterology & Hepatology
Lin Chang, William D. Chey, Aamer Imdad, Christopher V. Almario, Adil E. Bharucha, Susan Diem, Katarina B. Greer, Brian Hanson, Lucinda A. Harris, Cynthia Ko, M. Hassan Murad, Amit Patel, Eric D. Shah, Anthony J. Lembo, Shahnaz Sultan
Summary: This article is a clinical practice guideline for the pharmacological treatment of chronic idiopathic constipation (CIC) in adults. It provides evidence-based practice recommendations, including the use of polyethylene glycol, sodium picosulfate, linaclotide, plecanatide, and prucalopride. The article also highlights limitations and gaps in the evidence to guide future research opportunities and improve patient care.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Endocrinology & Metabolism
Zhanna Belaya, Liudmila Rozhinskaya, Ivan Dedov, Oksana Drapkina, Valentin Fadeev, Olga Golounina, Olga Lesnyak, Elizaveta Mamedova, Galina Melnichenko, Alexey Petraikin, Svetlana Rodionova, Irina Skripnikova, Olga Tkacheva, Natalia Toroptsova, Svetlana Yureneva, John A. Kanis
Summary: The key statements of the Russian clinical guidelines on the diagnosis and treatment of osteoporosis have been summarized. These guidelines were developed by key professional associations in Russia and approved by the Ministry of Health. They provide a practical tool for healthcare professionals involved in managing patients with osteoporosis.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Briana M. Nosal, Junichi R. Sakaki, Zachary Macdonald, Kyle Mahoney, Kijoon Kim, Matthew Madore, Staci Thornton, Thi Dong Binh Tran, George Weinstock, Elaine Choung-Hee Lee, Ock K. Chun
Summary: This study aimed to examine the dose-dependent effects of blackcurrant supplementation on preventing bone loss in adult women. The results showed that blackcurrant supplementation decreased the loss of whole-body bone mineral density and increased the marker of bone formation, P1NP. Further studies with larger samples and different skeletal conditions are needed to confirm these findings.
Review
Cardiac & Cardiovascular Systems
Martha Gulati, Phillip D. Levy, Debabrata Mukherjee, Ezra Amsterdam, Deepak L. Bhatt, Kim K. Birtcher, Ron Blankstein, Jack Boyd, Renee P. Bullock-Palmer, Theresa Conejo, Deborah B. Diercks, Federico Gentile, John P. Greenwood, Erik P. Hess, Steven M. Hollenberg, Wael A. Jaber, Hani Jneid, Jose A. Joglar, David A. Morrow, Robert E. O'Connor, Michael A. Ross, Leslee J. Shaw
Summary: The clinical practice guideline provides recommendations and algorithms for clinicians to assess and diagnose chest pain in adult patients based on contemporary evidence, emphasizing risk stratification and diagnostic workup, and recommending shared decision-making with patients.
Article
Cardiac & Cardiovascular Systems
Martha Gulati, Phillip D. Levy, Debabrata Mukherjee, Ezra Amsterdam, Deepak L. Bhatt, Kim K. Birtcher, Ron Blankstein, Jack Boyd, Renee P. Bullock-Palmer, Theresa Conejo, Deborah B. Diercks, Federico Gentile, John P. Greenwood, Erik P. Hess, Steven M. Hollenberg, Wael A. Jaber, Hani Jneid, Jose A. Joglar, David A. Morrow, Robert E. O'Connor, Michael A. Ross, Leslee J. Shaw
Summary: The executive summary of the clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain in adult patients. Recommendations are based on contemporary evidence, with a focus on risk stratification, diagnostic workup, cost-value considerations, and shared decision-making with patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Urology & Nephrology
Alayne D. Markland, Camille P. Vaughan, Alison J. Huang, Eunjung Kim, Vadim Y. Bubes, Vin Tangpricha, Julie R. Buring, I-Min Lee, Nancy R. Cook, JoAnn E. Manson, Francine Grodstein
Summary: The purpose of this study was to evaluate the effectiveness of vitamin D supplementation in preventing or treating overactive bladder and urinary incontinence in men. The results showed that overall, vitamin D supplementation did not improve overactive bladder or urinary incontinence compared to placebo. However, there were inconsistent findings when vitamin D supplements were used in men with lower levels of 25-hydroxyvitamin D.
JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Eric Walton, Sina Abhari, Vin Tangpricha, Cameron Futral, Akanksha Mehta
Summary: This study investigated family planning and fertility counseling perspectives of reproductive-age gender diverse adults and youth pursuing gender affirming hormone therapy. The results showed that individuals interested in or uncertain about future parenthood were more likely to consider cryopreservation and report inadequate family planning counseling. Therefore, current counseling practices may be insufficient and referral to a fertility specialist should be considered.
Review
Endocrinology & Metabolism
Renata Arrington-Sanders, Nathan T. Connell, Devin Coon, Nadia Dowshen, Anna L. Goldman, Zil Goldstein, Frances Grimstad, Noelle Marie Javier, Ellie Kim, Martina Murphy, Tonia Poteat, Asa Radix, Aviva Schwartz, Colt St Amand, Carl G. Streed Jr, Vin Tangpricha, Mabel Toribio, Robert H. Goldstein
Summary: Gender affirming hormone therapy (GAHT) improves mental health outcomes in transgender persons, but the risk of venous thromboembolism (VTE) should be considered, especially during long-term therapy and perioperative period. Hormone formulation, dosing, route, and duration of therapy can impact thromboembolic risk, and individualized risk assessment is necessary to avoid stopping GAHT due to concerns about VTE risk.
ENDOCRINE PRACTICE
(2023)
Editorial Material
Endocrinology & Metabolism
Vin Tangpricha
ENDOCRINE PRACTICE
(2023)
Article
Public, Environmental & Occupational Health
Sanjana Pampati, W. Dana Flanders, Qi Zhang, Brian K. Ahmedani, Shalender Bhasin, Darios Getahun, Timothy L. Lash, Courtney McCracken, David E. Sandberg, Michael J. Silverberg, Vin Tangpricha, Suma Vupputuri, Michael Goodman
Summary: Comparison between self-inflicted injuries among transgender and gender diverse (TGD) youth and their cisgender peers reveals that TGD individuals are more likely to engage in self-harm and have multiple mental health diagnoses. Universal suicide prevention efforts are necessary for all youth, including those without mental health issues, with intensified efforts for TGD youth and those with mental health diagnoses.
ANNALS OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Lena Chu, Sarah Gold, Carlyn Harris, Leslie Lawley, Pranav Gupta, Vin Tangpricha, Michael Goodman, Howa Yeung
Summary: This retrospective cohort study aimed to assess the incidence and predictors of acne among transgender adolescents receiving testosterone. It found that 54% of the patients who did not have baseline acne developed acne within 1 year of testosterone initiation. Patients who used progestin prior to or during follow-up were more likely to develop acne. Therefore, transgender adolescents starting testosterone, particularly those taking progestin, should be monitored for acne development and treated proactively.
ENDOCRINE PRACTICE
(2023)
Correction
Nutrition & Dietetics
M. D. Kearns, J. N. G. Binongo, D. Watson, J. A. Alvarez, D. Lodin, T. R. Ziegler, V. Tangpricha
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Endocrinology & Metabolism
Pranav Gupta, Briana C. Patterson, Lena Chu, Sarah Gold, Seth Amos, Howa Yeung, Michael Goodman, Vin Tangpricha
Summary: This study investigated the proportion and reasons for discontinuation of gender-affirming hormone therapy (GAHT) in transgender and gender diverse (TGD) individuals. The results showed that only a small percentage of participants discontinued GAHT, and the main reason was achieving desired treatment effects. This suggests that GAHT discontinuation is low when therapy follows the guidelines of the Endocrine Society.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Urology & Nephrology
Meron Siira, Darios Getahun, Michael J. Silverberg, Vin Tangpricha, Michael Goodman, Howa Yeung
Summary: This study examined patient satisfaction with current gender-affirming hormone therapy and their goals for additional hormone therapy. The majority of participants were satisfied with their current therapy, but transfeminine individuals and older participants were less likely to report satisfaction. Transfeminine individuals were more likely to plan for additional treatment to achieve goals such as breast size growth and feminine body fat distribution, while transmasculine individuals aimed for reducing dysphoria and masculine body fat distribution.
JOURNAL OF SEXUAL MEDICINE
(2023)
Article
Computer Science, Information Systems
Carl G. Streed Jr, Dana King, Chris Grasso, Sari L. Reisner, Kenneth H. Mayer, Guneet K. Jasuja, Tonia Poteat, Monica Mukherjee, Ayelet Shapira-Daniels, Howard Cabral, Vin Tangpricha, Michael K. Paasche-Orlow, Emelia J. Benjamin
Summary: The study aims to validate an algorithm for identifying transgender and gender diverse (TGD) patients within electronic health record (EHR) data and evaluate its accuracy. The algorithm was validated in an EHR data set with self-reported gender identity using TGD-related diagnosis and procedure codes, and hormone therapy prescription data. The results showed that the algorithm had good sensitivity, specificity, positive predictive value, and negative predictive value in identifying TGD patients in administrative data. Further categorization based on prescription data also had high accuracy.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Endocrinology & Metabolism
Malinda Wu, Anirudh Bhimavarapu, Jessica A. Alvarez, William R. Hunt, Vin Tangpricha
Summary: People with cystic fibrosis have increased risk for low bone mineral density and CF-related bone disease due to chronic inflammation and infection. This study suggests that vitamin D supplementation during acute pulmonary exacerbation may help reduce the risk for CF-related bone disease by decreasing markers of bone turnover.
Article
Endocrinology & Metabolism
E. Michael Lewiecki, Edward Czerwinski, Chris Recknor, Anna Strzelecka, Guillermo Valenzuela, Mary Lawrence, Stuart Silverman, Jose Cardona, Susan M. Nattrass, Neil Binkley, Miriam Annett, Leny Pearman, Bruce Mitlak
Summary: This study evaluated the safety and efficacy of the abaloparatide microstructured transdermal system (abaloparatide-sMTS) as an alternative to subcutaneous injection. The results showed that the abaloparatide-sMTS was not noninferior to the subcutaneous injection in terms of lumbar spine bone density at 12 months, but both treatments significantly increased lumbar spine and total hip bone density.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Review
Endocrinology & Metabolism
E. Michael Lewiecki, Teresita Bellido, John P. Bilezikian, Jacques P. Brown, Azeez Farooki, Christopher S. Kovacs, Brendan Lee, William D. Leslie, Michael R. McClung, Mark L. Prasarn, Deborah E. Sellmeyer
Summary: The 23rd annual Santa Fe Bone Symposium brought together attendees from various states and countries to discuss topics related to osteoporosis and other bone diseases. The event included plenary presentations, panel discussions, workshops, and oral presentations of research abstracts.
JOURNAL OF CLINICAL DENSITOMETRY
(2023)
Correction
Multidisciplinary Sciences
Pichatorn Suppakitjanusant, Nittaya Kasemkosin, Alisa K. Sivapiromrat, Samuel Weinstein, Boonsong Ongphiphadhanakul, William R. Hunt, Viranuj Sueblinvong, Vin Tangpricha
SCIENTIFIC REPORTS
(2023)
Article
Psychology, Clinical
Hayley Braun, Elaine C. Thompson, Qi Zhang, Vin Tangpricha, Michael Goodman, Howa Yeung
Summary: The prevalence of psoriasis among transgender individuals is similar to that in the general population, but further longitudinal research is needed to explore the potential association between psoriasis and gender-affirming hormone therapy.
TRANSGENDER HEALTH
(2023)