期刊
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
卷 88, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compmedimag.2021.101866
关键词
Breast cancer; Computational pathology; Multi-class image segmentation; Deep Multi-Magnification Network; Partial annotation
In this paper, a Deep Multi-Magnification Network trained by partial annotation is proposed for automated multi-class tissue segmentation using a set of patches from multiple magnifications in digitized whole slide images. The proposed architecture outperforms other single and multi-magnification-based architectures by achieving the highest mean intersection-over-union, which can facilitate pathologists' assessments of breast cancer.
Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing histologic slides prepared from formalin-fixed tissue. In this paper, we present Deep Multi-Magnification Network trained by partial annotation for automated multi-class tissue segmentation by a set of patches from multiple magnifications in digitized whole slide images. Our proposed architecture with multi-encoder, multi-decoder, and multi-concatenation outperforms other single and multi-magnification-based architectures by achieving the highest mean intersection-over-union, and can be used to facilitate pathologists' assessments of breast cancer.
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