Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
出版年份 2021 全文链接
标题
Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma
作者
关键词
high-grade glioma, H3.3G34R, ATRX, TP53, NOTCH2NL, Pluripotent stem cells, cancer models, histone-mutant glioma, interneuron progenitors, ventral forebrain, hindbrain progenitors
出版物
Cell Stem Cell
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-02-24
DOI
10.1016/j.stem.2021.02.003
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Evolution of human brain-size associated NOTCH2NL genes proceeds towards reduced protein levels
- (2020) Gerrald A Lodewijk et al. MOLECULAR BIOLOGY AND EVOLUTION
- Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression
- (2020) Siddhant U. Jain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation
- (2018) Ikuo K. Suzuki et al. CELL
- Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis
- (2018) Ian T. Fiddes et al. CELL
- The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update
- (2018) Enis Afgan et al. NUCLEIC ACIDS RESEARCH
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
- (2018) André Kahles et al. CANCER CELL
- Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma
- (2018) Hsiao P. J. Voon et al. Nature Communications
- Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex
- (2017) Tomasz J. Nowakowski et al. SCIENCE
- Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2
- (2017) Aram S. Modrek et al. Cell Reports
- The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing
- (2017) Jinyeong Lim et al. Scientific Reports
- SplAdder: identification, quantification and testing of alternative splicing events from RNA-Seq data
- (2016) André Kahles et al. BIOINFORMATICS
- ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma
- (2016) Carl Koschmann et al. Science Translational Medicine
- Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells
- (2015) Simon J. Elsässer et al. NATURE
- Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles
- (2015) Bushra Raj et al. NEURON
- Notching on Cancer’s Door: Notch Signaling in Brain Tumors
- (2015) Marcin Teodorczyk et al. Frontiers in Oncology
- CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
- (2014) Yuki Naito et al. BIOINFORMATICS
- Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
- (2014) S. Bae et al. BIOINFORMATICS
- BS69/ZMYND11 Reads and Connects Histone H3.3 Lysine 36 Trimethylation-Decorated Chromatin to Regulated Pre-mRNA Processing
- (2014) Rui Guo et al. MOLECULAR CELL
- Dissecting neural differentiation regulatory networks through epigenetic footprinting
- (2014) Michael J. Ziller et al. NATURE
- ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
- (2014) Hong Wen et al. NATURE
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
- (2014) Kosuke Funato et al. SCIENCE
- Directed Differentiation and Functional Maturation of Cortical Interneurons from Human Embryonic Stem Cells
- (2013) Asif M. Maroof et al. Cell Stem Cell
- H3.3 G34R mutations in pediatric primitive neuroectodermal tumors of central nervous system (CNS-PNET) and pediatric glioblastomas: possible diagnostic and therapeutic implications?
- (2013) Marco Gessi et al. JOURNAL OF NEURO-ONCOLOGY
- Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
- (2013) Sam Behjati et al. NATURE GENETICS
- Progenetix: 12 years of oncogenomic data curation
- (2013) Haoyang Cai et al. NUCLEIC ACIDS RESEARCH
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN
- (2013) Lynn Bjerke et al. Cancer Discovery
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
- (2012) Dong-Anh Khuong-Quang et al. ACTA NEUROPATHOLOGICA
- Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
- (2012) Dominik Sturm et al. CANCER CELL
- Genetic visualization of notch signaling in mammalian neurogenesis
- (2012) Itaru Imayoshi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
- (2010) Aaron D. Goldberg et al. CELL
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells
- (2009) Eric Campeau et al. PLoS One
- Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
- (2008) Y. Elkabetz et al. GENES & DEVELOPMENT
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