Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis

Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

(2020) Fanny Matheis et al.   CELL

The Immune Function of Tuft Cells at Gut Mucosal Surfaces and Beyond

(2019) Hung-An Ting et al.   JOURNAL OF IMMUNOLOGY

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity

(2019) Qingkun Liu et al.   NATURE IMMUNOLOGY

Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy

(2019) Roman Szabo et al.   DEVELOPMENT

Gut macrophages: key players in intestinal immunity and tissue physiology

(2019) Paul A. Muller et al.   CURRENT OPINION IN IMMUNOLOGY

A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

(2018) Christoph Schneider et al.   CELL

An Immunocompetent Mouse Model of Zika Virus Infection

(2018) Matthew J. Gorman et al.   Cell Host & Microbe

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

Dynamics of Tissue-Specific CD8+ T Cell Responses during West Nile Virus Infection

(2018) Renan Aguilar-Valenzuela et al.   JOURNAL OF VIROLOGY

Epidemiology and ecology of West Nile virus in sub-Saharan Africa

(2018) Waidi F. Sule et al.   Parasites & Vectors

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tropism for tuft cells determines immune promotion of norovirus pathogenesis

(2018) Craig B. Wilen et al.   SCIENCE

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

(2018) Larissa B. Thackray et al.   Cell Reports

Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses

(2018) James P. White et al.   CELL

Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function

(2018) Shiyang Li et al.   IMMUNITY

Helminth-induced IL-4 expands bystander memory CD8+ T cells for early control of viral infection

(2018) Marion Rolot et al.   Nature Communications

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

(2018) Tobias Straub et al.   Nature Communications

An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections

(2018) Laura A. VanBlargan et al.   Cell Reports

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections

(2018) Isaac J. Jensen et al.   PLoS Pathogens

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

(2017) Amanda J. McFarlane et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intestinal helminth infection impacts the systemic distribution and function of the naive lymphocyte pool

(2017) I L King et al.   Mucosal Immunology

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Clinical and Experimental Sepsis Impairs CD8 T-Cell-Mediated Immunity

(2016) Derek B. Danahy et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

(2016) François Gerbe et al.   NATURE

Translocation and dissemination of commensal bacteria in post-stroke infection

(2016) Dragana Stanley et al.   NATURE MEDICINE

Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut

(2016) M. R. Howitt et al.   SCIENCE

Activated Type 2 Innate Lymphoid Cells Regulate Beige Fat Biogenesis

(2015) Min-Woo Lee et al.   CELL

Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis

(2015) Leticia Monin et al.   JOURNAL OF CLINICAL INVESTIGATION

Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

(2015) Jakob von Moltke et al.   NATURE

Helminths and the microbiota: parts of the hygiene hypothesis

(2015) P. Loke et al.   PARASITE IMMUNOLOGY

Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy

(2015) Andrew L. Kau et al.   Science Translational Medicine

Splenic Macrophage Subsets and Their Function during Blood-Borne Infections

(2015) Henrique Borges da Silva et al.   Frontiers in Immunology

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

(2014) Christopher J. Oliphant et al.   IMMUNITY

Lymphocytic choriomeningitis virus persistence promotes effector-like memory differentiation and enhances mucosal T cell distribution

(2014) Lalit K. Beura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Flaviviruses, an expanding threat in public health: focus on dengue, West Nile, and Japanese encephalitis virus

(2014) Carlo Amorin Daep et al.   JOURNAL OF NEUROVIROLOGY

S. mansoni Bolsters Anti-Viral Immunity in the Murine Respiratory Tract

(2014) Sebastian Scheer et al.   PLoS One

Helminth infection reactivates latent  -herpesvirus via cytokine competition at a viral promoter

(2014) T. A. Reese et al.   SCIENCE

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

(2014) L. C. Osborne et al.   SCIENCE

Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin

(2014) Judith E. Allen et al.   SEMINARS IN IMMUNOLOGY

Allergic Inflammation—Innately Homeostatic

(2014) Laurence E. Cheng et al.   Cold Spring Harbor Perspectives in Biology

Effect of helminth-induced immunity on infections with microbial pathogens

(2013) Padmini Salgame et al.   NATURE IMMUNOLOGY

Medical Risk Factors for Severe West Nile Virus Disease, United States, 2008–2010

(2012) Nicole P. Lindsey et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Immunity to the model intestinal helminth parasite Heligmosomoides polygyrus

(2012) Lisa A. Reynolds et al.   Seminars in Immunopathology

Host Genetic Risk Factors for West Nile Virus Infection and Disease Progression

(2011) Abigail W. Bigham et al.   PLoS One

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion

(2009) G. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of EpCAM as the Gene for Congenital Tufting Enteropathy

(2008) Mamata Sivagnanam et al.   GASTROENTEROLOGY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE