期刊
BIOMEDICINE & PHARMACOTHERAPY
卷 134, 期 -, 页码 -出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.biopha.2020.111153
关键词
Cancer; Nanobiomedicine; Microfluidic; Biosensing; Circulating tumor cells (CTCs); Biomedical analysis; Biotechnology
资金
- Tabriz University of Medical Sciences
This review provides an overview of the current state of microfluidic biosensors for screening CTCs and briefly discusses the future outlook for the development of microfluidics biosensing.
Cancer metastasis is one of the foremost causes of cancer incidence and fatality in the whole of the world. Circulating tumor cells (CTC) have been confirmed to be among the most significant stimuli of metastasis in recent years and presently are the subject of extensive research aiming to be accurately identified by using biological and physical properties. Among the various studies conducted for isolation, identification, and characterization of CTCs, microfluidic systems have aroused great attention owing to their unique advantages such as low-cost, simplicity, reduction in reagent consumption, miniaturization, fast and precise control. The purpose of this review is to provide an overview of current state of the microfluidic biosensors for the screening of CTCs. Additionally, given the recent progress in this field, future outlook for the development of the micro fluidics biosensing is briefly discussed.
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