4.7 Article

ConPlot: web-based application for the visualization of protein contact maps integrated with other data

期刊

BIOINFORMATICS
卷 37, 期 17, 页码 2763-2765

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OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btab049

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  1. Biotechnology and Biological Sciences Research Council [BB/S007105/1]
  2. BBSRC [BB/S007105/1] Funding Source: UKRI

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ConPlot is a web-based application for convenient display and analysis of contact maps and distograms in protein bioinformatics, which allows for integration of predicted contact data with other predictions to facilitate inference of structural features. This novel visualization enables easier interpretation of predicted contact maps by displaying multiple colored tracks representing other sequence-based predictions near the contact map diagonal.
A ummary: Covariance-based predictions of residue contacts and inter-residue distances are an increasingly popular data type in protein bioinformatics. Here we present ConPlot, a web-based application for convenient display and analysis of contact maps and distograms. Integration of predicted contact data with other predictions is often required to facilitate inference of structural features. ConPlot can therefore use the empty space near the contact map diagonal to display multiple coloured tracks representing other sequence-based predictions. Popular file formats are natively read and bespoke data can also be flexibly displayed. This novel visualization will enable easier interpretation of predicted contact maps.

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