ATP biphasically modulates LLPS of SARS-CoV-2 nucleocapsid protein and specifically binds its RNA-binding domain

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A proposed role for the SARS‐CoV‐2 nucleocapsid protein in the formation and regulation of biomolecular condensates

(2020) Sean M. Cascarina et al.   FASEB JOURNAL

The SARS-CoV-2 N protein is a good component in a vaccine

(2020) Gustaf Ahlén et al.   JOURNAL OF VIROLOGY

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

(2020) Theodora Myrto Perdikari et al.   EMBO JOURNAL

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids

(2019) Jian Kang et al.   PLOS BIOLOGY

ATP binds nucleic-acid-binding domains beyond RRM fold

(2019) Yuan He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation

(2019) Mei Dang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

The Coronavirus Nucleocapsid Is a Multifunctional Protein

(2014) Ruth McBride et al.   Viruses-Basel

The Coronavirus Nucleocapsid Protein Is Dynamically Associated with the Replication-Transcription Complexes

(2010) M. H. Verheije et al.   JOURNAL OF VIROLOGY