Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study

Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8

(2020) Leanne de Kock et al.   ACTA NEUROPATHOLOGICA

Pineoblastoma in children less than six years of age: The Head Start I, II, and III experience

(2020) Mohamed S. Abdelbaki et al.   PEDIATRIC BLOOD & CANCER

Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy

(2020) Philip E. D. Chung et al.   Nature Communications

ETMR-03. THE ROLE OF FOXR2 IN PEDIATRIC BRAIN CANCER

(2020) Felix Schmitt-Hoffner et al.   NEURO-ONCOLOGY

Recurrent KBTBD4 small in-frame insertions and absence of DROSHA deletion or DICER1 mutation differentiate pineal parenchymal tumor of intermediate differentiation (PPTID) from pineoblastoma

(2019) Julieann C. Lee et al.   ACTA NEUROPATHOLOGICA

An update on the central nervous system manifestations of DICER1 syndrome

(2019) Leanne de Kock et al.   ACTA NEUROPATHOLOGICA

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

(2019) Elke Pfaff et al.   ACTA NEUROPATHOLOGICA

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2012–2016

(2019) Quinn T Ostrom et al.   NEURO-ONCOLOGY

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials

(2019) Anthony P. Y. Liu et al.   ACTA NEUROPATHOLOGICA

Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study

(2019) Bryan K. Li et al.   ACTA NEUROPATHOLOGICA

The molecular landscape of ETMR at diagnosis and relapse

(2019) Sander Lambo et al.   NATURE

Molecular subgrouping of atypical teratoid/rhabdoid tumors—a reinvestigation and current consensus

(2019) Ben Ho et al.   NEURO-ONCOLOGY

DNA methylation-based classification of central nervous system tumours

(2018) David Capper et al.   NATURE

Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma

(2018) Sara Bolin et al.   ONCOGENE

Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma

(2018) Matija Snuderl et al.   Nature Communications

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children’s Oncology Group Randomized ACNS0332 Trial

(2018) Eugene I. Hwang et al.   JOURNAL OF CLINICAL ONCOLOGY

Pineoblastoma—The Experience at St. Jude Children's Research Hospital

(2017) Kara A. Parikh et al.   NEUROSURGERY

Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome

(2016) David R. Raleigh et al.   NEURO-ONCOLOGY

Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data

(2016) Martin Mynarek et al.   NEURO-ONCOLOGY

Patterns of care and survival outcomes in patients with pineal parenchymal tumor of intermediate differentiation: An individual patient data analysis

(2016) Supriya Mallick et al.   RADIOTHERAPY AND ONCOLOGY

FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis

(2016) Xu Li et al.   Cell Reports

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

(2015) Felix Sahm et al.   ACTA NEUROPATHOLOGICA

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

(2014) Martin J. Aryee et al.   BIOINFORMATICS

BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma

(2013) P. Bandopadhayay et al.   CLINICAL CANCER RESEARCH

Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases

(2013) Peter Canning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GermlineDICER1mutation and associated loss of heterozygosity in a pineoblastoma: Figure 1

(2012) Nelly Sabbaghian et al.   JOURNAL OF MEDICAL GENETICS

The long-term postsurgical prognosis of patients with pineoblastoma

(2011) Matthew Tate et al.   CANCER

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

A flexible R package for nonnegative matrix factorization

(2010) Renaud Gaujoux et al.   BMC BIOINFORMATICS