NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay

De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

(2020) Simon Ng et al.   ACS Medicinal Chemistry Letters

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

(2019) Anthony W. Partridge et al.   MOLECULES

Real-Time Imaging and Quantification of Peptide Uptake in Vitro and in Vivo

(2019) Hacer Karatas et al.   ACS Chemical Biology

The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors

(2019) Srinivasaraghavan Kannan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide

(2019) Patrick G. Dougherty et al.   JOURNAL OF MEDICINAL CHEMISTRY

Getting in: emerging methods and design principles for cell-penetrant peptides

(2018) Leila Peraro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Label-Free Confocal Raman Mapping of Transportan in Melanoma Cells

(2018) Patrick J. Cosme et al.   MOLECULAR PHARMACEUTICS

Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

(2018) Sofie Fogh Hedegaard et al.   Scientific Reports

Cell penetrating peptides: A concise review with emphasis on biomedical applications

(2018) Hossein Derakhshankhah et al.   BIOMEDICINE & PHARMACOTHERAPY

Cell Penetration Profiling Using the Chloroalkane Penetration Assay

(2018) Leila Peraro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Future of Bioorthogonal Chemistry

(2018) Neal K. Devaraj   ACS Central Science

Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy

(2017) Leila Peraro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity

(2017) Daniela Kalafatovic et al.   MOLECULES

Comprehensive computational design of ordered peptide macrocycles

(2017) Parisa Hosseinzadeh et al.   SCIENCE

A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo

(2016) Maruti Uppalapati et al.   ACS Chemical Biology

Discovery and Mechanism of Highly Efficient Cyclic Cell-Penetrating Peptides

(2016) Ziqing Qian et al.   BIOCHEMISTRY

Passive Membrane Permeability in Cyclic Peptomer Scaffolds Is Robust to Extensive Variation in Side Chain Functionality and Backbone Geometry

(2016) Akihiro Furukawa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantitative fluorescence spectroscopy and flow cytometry analyses of cell-penetrating peptides internalization pathways: optimization, pitfalls, comparison with mass spectrometry quantification

(2016) Françoise Illien et al.   Scientific Reports

NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions

(2015) Thomas Machleidt et al.   ACS Chemical Biology

Deciphering the Cellular Targets of Bioactive Compounds Using a Chloroalkane Capture Tag

(2015) Rachel Friedman Ohana et al.   ACS Chemical Biology

HaloTag Technology: A Versatile Platform for Biomedical Applications

(2015) Christopher G. England et al.   BIOCONJUGATE CHEMISTRY

Beyond cyclosporine A: conformation-dependent passive membrane permeabilities of cyclic peptide natural products

(2015) Christopher L Ahlbach et al.   Future Medicinal Chemistry

Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products

(2015) William M. Hewitt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism Matters: A Taxonomy of Cell Penetrating Peptides

(2015) W. Berkeley Kauffman et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Uptake of Arginine-Rich Cell-Penetrating Peptides: Putting the Puzzle Together

(2014) Roland Brock   BIOCONJUGATE CHEMISTRY

The Efficacies of Cell-Penetrating Peptides in Accumulating in Large Unilamellar Vesicles Depend on their Ability To Form Inverted Micelles

(2014) Jean-Marie Swiecicki et al.   CHEMBIOCHEM

Glycosaminoglycans in the cellular uptake of drug delivery vectors – Bystanders or active players?

(2014) Marco E. Favretto et al.   JOURNAL OF CONTROLLED RELEASE

Discovering Protein Interactions and Characterizing Protein Function Using HaloTag Technology

(2014) Danette L. Daniels et al.   Jove-Journal of Visualized Experiments

A Membrane-Translocating Peptide Penetrates into Bilayers without Significant Bilayer Perturbations

(2013) Juan Cruz et al.   BIOPHYSICAL JOURNAL

Cell-penetrating peptides: 20 years later, where do we stand?

(2013) Chérine Bechara et al.   FEBS LETTERS

Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy

(2013) Yong S. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

(2012) Mary P. Hall et al.   ACS Chemical Biology

Stapled Peptides with Improved Potency and Specificity That Activate p53

(2012) Christopher J. Brown et al.   ACS Chemical Biology

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

Recombinant peptide constructs for targeted cell penetrating peptide-mediated delivery

(2012) Jennica L. Zaro et al.   JOURNAL OF CONTROLLED RELEASE

Spontaneous Membrane-Translocating Peptides by Orthogonal High-Throughput Screening

(2011) Jessica R. Marks et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determination of Penetratin Secondary Structure in Live Cells with Raman Microscopy

(2009) Jing Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nuclear Localization of Cell-Penetrating Peptides Is Dependent on Endocytosis Rather Than Cytosolic Delivery in CHO Cells

(2009) Jennica L. Zaro et al.   MOLECULAR PHARMACEUTICS

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Comparison of Cellular Uptake Using 22 CPPs in 4 Different Cell Lines

(2008) Judith Mueller et al.   BIOCONJUGATE CHEMISTRY