Mitochondrial dysfunction in neurological disorders: Exploring mitochondrial transplantation

Deciphering the Iron Side of Stroke: Neurodegeneration at the Crossroads Between Iron Dyshomeostasis, Excitotoxicity, and Ferroptosis

(2019) Núria DeGregorio-Rocasolano et al.   Frontiers in Neuroscience

Post mortem examination of Parkinson’s disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus

(2019) Anna Mallach et al.   FASEB JOURNAL

Mitochondria Are a subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells

(2019) Florian Puhm et al.   CIRCULATION RESEARCH

Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer

(2019) Trenton Lippert et al.   CNS Neuroscience & Therapeutics

Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer

(2019) Longfei Gao et al.   Frontiers in Cellular Neuroscience

STYK1/NOK correlates with ferroptosis in non-small cell lung carcinoma

(2019) Yuanyang Lai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells

(2018) David N. DeHart et al.   BIOCHEMICAL PHARMACOLOGY

Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture

(2018) Nathalia M. de Vasconcelos et al.   CELL DEATH AND DIFFERENTIATION

Iron and Alzheimer’s Disease: An Update on Emerging Mechanisms

(2018) Darius J.R. Lane et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury

(2018) Jenna L. Gollihue et al.   JOURNAL OF NEUROTRAUMA

Brief Reports: Protective Effects of Endothelial Progenitor Cell-Derived Extracellular Mitochondria in Brain Endothelium

(2018) Kazuhide Hayakawa et al.   STEM CELLS

Extracellular Mitochondria for Therapy and Diagnosis in Acute Central Nervous System Injury

(2018) Kazuhide Hayakawa et al.   JAMA Neurology

Inhibition of ferroptosis attenuates tissue damage and improves long-term outcomes after traumatic brain injury in mice

(2018) Bao-Shu Xie et al.   CNS Neuroscience & Therapeutics

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

(2018) Raimunda S. S. Azevedo et al.   Scientific Reports

Mitochondria in Ischemic Stroke: New Insight and Implications

(2018) Fan Liu et al.   Aging and Disease

Muscle-derived autologous mitochondrial transplantation: A novel strategy for treating cerebral ischemic injury

(2018) Zhanqin Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation

(2018) Yin Yao et al.   Stem Cell Reports

Epidemiology of Parkinson’s disease

(2017) Ole-Bjørn Tysnes et al.   JOURNAL OF NEURAL TRANSMISSION

Autologous mitochondrial transplantation for dysfunction after ischemia-reperfusion injury

(2017) Sitaram M. Emani et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Intravenous administration of mitochondria for treating experimental Parkinson's disease

(2017) Xianxun Shi et al.   MITOCHONDRION

Prospects for therapeutic mitochondrial transplantation

(2017) Jenna L. Gollihue et al.   MITOCHONDRION

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy

(2017) Rebecca J. Wilson et al.   MITOCHONDRION

Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder

(2017) Odile Robicsek et al.   SCHIZOPHRENIA BULLETIN

Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich’s ataxia

(2017) Celine J. Rocca et al.   Science Translational Medicine

Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival

(2017) Jordan Rose et al.   TOXICOLOGY

Mitochondrial fusion, fission, and mitochondrial toxicity

(2017) Joel N. Meyer et al.   TOXICOLOGY

Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability

(2017) Thomas Briston et al.   Scientific Reports

Transferring Xenogenic Mitochondria Provides Neural Protection against Ischemic Stress in Ischemic Rat Brains

(2016) Po-Jui Huang et al.   CELL TRANSPLANTATION

Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission

(2016) Shotaro Saita et al.   GENES TO CELLS

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

(2016) Bruce Do Van et al.   NEUROBIOLOGY OF DISEASE

Long range physical cell-to-cell signalling via mitochondria inside membrane nanotubes: a hypothesis

(2016) Felix Scholkmann   Theoretical Biology and Medical Modelling

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

(2016) Tanja Krainz et al.   ACS Central Science

Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection

(2016) Douglas B. Cowan et al.   PLoS One

Evolution of Mitochondria as Signaling Organelles

(2015) Navdeep S. Chandel   Cell Metabolism

The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury

(2015) Andrew P. Halestrap et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Fluid Intake Related to Brain Edema in Acute Middle Cerebral Artery Infarction

(2015) Pornpatr A. Dharmasaroja   Translational Stroke Research

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

A NovelMitoTimerReporter Gene for Mitochondrial Content, Structure, Stress, and Damagein Vivo

(2014) Rhianna C. Laker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mdivi-1 Prevents Apoptosis Induced by Ischemia–Reperfusion Injury in Primary Hippocampal Cells via Inhibition of Reactive Oxygen Species–Activated Mitochondrial Pathway

(2014) Jinying Wang et al.   Journal of Stroke & Cerebrovascular Diseases

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer

(2014) Kaiming Liu et al.   MICROVASCULAR RESEARCH

Direct Human Mitochondrial Transfer: A Novel Concept Based on the Endosymbiotic Theory

(2014) T. Kitani et al.   TRANSPLANTATION PROCEEDINGS

Necroptosis: is there a role for mitochondria?

(2014) Kurt D. Marshall et al.   Frontiers in Physiology

Transplantation of autologously derived mitochondria protects the heart from ischemia-reperfusion injury

(2013) Akihiro Masuzawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

(2013) Valasani Koteswara Rao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

(2013) Amos A Fatokun et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of Mitochondrial Fission and Fusion

(2013) A. M. van der Bliek et al.   Cold Spring Harbor Perspectives in Biology

Genetics of Parkinson's Disease

(2013) C. Klein et al.   Cold Spring Harbor Perspectives in Medicine

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Cell Therapy for Stroke: Emphasis on Optimizing Safety and Efficacy Profile of Endothelial Progenitor Cells

(2012) Yuji Kaneko et al.   CURRENT PHARMACEUTICAL DESIGN

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

(2012) Mohammad Naimul Islam et al.   NATURE MEDICINE

Mitochondria: isolation, structure and function

(2011) Martin Picard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

(2011) Wenjun Song et al.   NATURE MEDICINE

Ischemic Cerebral Damage

(2011) Jeannette Hofmeijer et al.   STROKE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondria, oxidative metabolism and cell death in stroke

(2009) Neil R. Sims et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

(2009) Rodrigo A. Quintanilla et al.   BRAIN RESEARCH BULLETIN

The Alzheimer's disease mitochondrial cascade hypothesis: An update

(2009) Russell H. Swerdlow et al.   EXPERIMENTAL NEUROLOGY

Injection of isolated mitochondria during early reperfusion for cardioprotection

(2008) James D. McCully et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

(2008) Alison Wood-Kaczmar et al.   PLoS One

Proteomic profiling of exosomes: Current perspectives

(2008) Richard J. Simpson et al.   PROTEOMICS