Review
Biochemistry & Molecular Biology
Se-Jin Jeong, Jong-Gil Park, Goo Taeg Oh
Summary: Increased oxidative stress is considered a common factor in the pathogenesis of cardiovascular disease, with precise regulation of ROS in cardiovascular cells essential for normal physiological functions. Antioxidant enzymes such as Prdxs play a crucial role in maintaining the balance of ROS levels and act as regulatory sensors of intracellular signals.
Article
Plant Sciences
Renata Biba, Petra Cvjetko, Mihaela Jakopcic, Bruno Komazec, Mirta Tkalec, Nino Dimitrov, Tajana Begovic, Biljana Balen
Summary: Plastic contamination is a pressing environmental issue due to the increasing production of disposable plastic products. In this study, onion roots were exposed to commercial polystyrene (PS-MPs) and polymethyl methacrylate microparticles (PMMA-MPs) to investigate their effects. The results showed that PS-MPs were more readily taken up by onion roots compared to PMMA-MPs. Both types of microparticles did not induce toxic effects on root growth, and PMMA-MPs even stimulated root growth. Antioxidant enzymes were activated in root cells after exposure to both types of microparticles.
Review
Chemistry, Multidisciplinary
Jingnan Zhao, Fanfan Guo, Lin Hou, Yongxing Zhao, Pengchao Sun
Summary: Inflammatory diseases are associated with high levels of ROS. Excess ROS leads to the polarization of microphages into the proinflammatory M1 phenotype and causes damage to DNA, proteins, and lipids, worsening the inflammatory response. Scavenging ROS to alleviate oxidative stress has proven to be an effective strategy for reversing inflammation. Inspired by natural antioxidant enzymes, electron transfer-based artificial antioxidant nanozymes have emerged as therapeutic agents for treating inflammatory diseases.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Biochemistry & Molecular Biology
Iwona Lukasik, Sylwia Golawska, Hubert Sytykiewicz
Summary: Changes in oxidative stress markers and antioxidant enzyme activities were studied in the black bean aphid. Winged adults showed lower oxidative stress marker levels and higher antioxidant enzyme activities, indicating adaptation to new host plants. Wingless females during spring migration showed increased marker levels and enzyme activities, suggesting biochemical adaptation to winter hosts.
Review
Nutrition & Dietetics
Kosar Valaei, Shima Taherkhani, Hamid Arazi, Katsuhiko Suzuki
Summary: Reactive oxygen species (ROS) play a crucial role in the pathophysiology of cardiac diseases, leading to cellular and molecular disorders that can result in heart dysfunction. New experimental treatments such as creatine supplementation, omega-3 fatty acids, and others have shown beneficial effects in improving oxidative stress.
Review
Biochemistry & Molecular Biology
Deyamira Matuz-Mares, Hector Riveros-Rosas, Maria Magdalena Vilchis-Landeros, Hector Vazquez-Meza
Summary: Cardiovascular diseases result in high mortality rates globally, with oxidative stress playing a key role in worsening patient conditions. Reactive oxygen and nitrogen species are generated during the development of these diseases, contributing to the deleterious effects on patients.
Review
Plant Sciences
Anna Ekner-Grzyb, Anna Duka, Tomasz Grzyb, Isabel Lopes, Jagna Chmielowska-Bak
Summary: Pollution of the environment with plastic is a significant concern in the modern world. Despite recycling methods, a substantial amount of plastic is still deposited in the environment. Nanoplastic, in particular, poses a serious danger as it can be effectively taken up and transported within organisms. It has been found to exert toxic effects on plants, mainly through oxidative response.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Yuanduo Wang, Piaopiao Tan, Liang Chang, Zheming Yue, Chaozhen Zeng, Mei Li, Zhixiang Liu, Xujie Dong, Mingli Yan
Summary: Exogenous proline treatment enhances the tolerance of Brassica juncea to cadmium by reducing cadmium accumulation and reestablishing redox homeostasis.
Article
Microbiology
Anjney Sharma, Xiu-Peng Song, Rajesh Kumar Singh, Anukool Vaishnav, Saurabh Gupta, Pratiksha Singh, Dao-Jun Guo, Krishan K. Verma, Yang-Rui Li
Summary: The overconsumption and irregular use of agrochemicals can have adverse effects on soil flora and non-target beneficial microorganisms. This study focused on the effects of a high dosage of fungicide on the survival of plant-beneficial rhizobacteria and their ability to promote plant growth. The results showed that the high dosage of fungicide decreased the cell growth and survival of the rhizobacteria and also reduced their plant growth promoting activities.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Yu-Ting Zhu, Cheng Wan, Ji-Hong Lin, Hans-Peter Hammes, Chun Zhang
Summary: Podocytopathies are kidney diseases driven by podocyte injury. This review highlights the crucial role of mitochondrial oxidative stress in the pathogenesis of podocytopathies and its relationship with cell death in podocytes. Exogenous antioxidants can protect podocytes from damage. The review aims to identify new targets for improving the treatment of podocytopathies.
Article
Biochemistry & Molecular Biology
Md Mahadi Hasan, Basmah M. Alharbi, Haifa Abdulaziz Sakit Alhaithloul, Awatif M. Abdulmajeed, Suliman Mohammed Alghanem, Amina A. M. Al-Mushhin, Mohammad Shah Jahan, Francisco J. Corpas, Xiang-Wen Fang, Mona H. Soliman
Summary: Excessive selenium induces toxicity in wheat plants, while spermine (Spm) and nitric oxide (NO) can mitigate selenium-induced stress by enhancing antioxidant defense and reducing selenium uptake. Combined treatment with Spm and NO shows potential for sustainable wheat production in selenium-contaminated areas.
Review
Plant Sciences
Rajesh Kumar Tewari, Nele Horemans, Masami Watanabe
Summary: Nitric oxide (NO) is now recognized as an essential regulatory molecule in plants, playing a key role in iron (Fe) homeostasis and alleviating oxidative stress. Further investigations are needed to explore the interaction of NO with intracellular target molecules to enhance internal Fe availability in plants.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Review
Biochemistry & Molecular Biology
Michael Amponsah-Offeh, Patrick Diaba-Nuhoho, Stephan Speier, Henning Morawietz
Summary: Hypertension is a major global health threat, and despite the availability of antihypertensive medications, resistance to treatment remains a problem. The renin-angiotensin-aldosterone system, immune system activation, and oxidative stress have been implicated in hypertension's pathogenesis. In addition to standard antihypertensive medications, antioxidants have been tested as a potential treatment. This review discusses the role of oxidative stress in hypertension and explores the use of antioxidants in its management.
Article
Biochemistry & Molecular Biology
Sylvia Maina, Da Hye Ryu, Jwa Yeong Cho, Da Seul Jung, Jai-Eok Park, Chu Won Nho, Gaymary Bakari, Gerald Misinzo, Je Hyeong Jung, Seung-Hoon Yang, Ho-Youn Kim
Summary: The study evaluated the effects of salt treatment and different light wavelengths on glucosinolates and phenolic compounds in Brassica carinata microgreens. The results showed that salt treatment and specific light conditions can enhance antioxidant activities, promote the accumulation of glucosinolates, and potentially treat and prevent oxidative stress and inflammatory disorders.
Review
Chemistry, Medicinal
Abu Mohammad Syed, Chetan Ram, Upadhyayula Suryanarayana Murty, Bidya Dhar Sahu
Summary: The article discusses the pathogenesis of cardiovascular diseases, emphasizing the cardiac protective effect of Nrf2, and the potential therapeutic possibilities of Nrf2 activators from herbal origin in treating cardiovascular diseases.
PHYTOTHERAPY RESEARCH
(2021)