Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

Interferon-independent STING signaling promotes resistance to HSV-1 in vivo

(2020) Lívia H. Yamashiro et al.   Nature Communications

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies

(2019) Trine H. Mogensen   Frontiers in Immunology

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

(2019) Xiang Gui et al.   NATURE

The emerging role of human TBK1 in virus-induced autophagy

(2019) Ahmad Liyana et al.   Autophagy

An antibody for analysis of autophagy induction

(2019) Wensheng Tian et al.   NATURE METHODS

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis

(2019) Fabien G. Lafaille et al.   NATURE MEDICINE

Autophagy balances inflammation in innate immunity

(2018) Vojo Deretic et al.   Autophagy

PopViz: a webserver for visualizing minor allele frequencies and damage prediction scores of human genetic variations

(2018) Peng Zhang et al.   BIOINFORMATICS

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection

(2018) Shen-Ying Zhang et al.   CELL

Defective RNA sensing by RIG-I in severe influenza virus infection

(2018) S. E. Jørgensen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

(2018) Thaneas Prabakaran et al.   EMBO JOURNAL

Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection

(2018) Bastian Zimmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mollaret meningitis

(2018) William F. Wright et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Clustal Omega for making accurate alignments of many protein sequences

(2017) Fabian Sievers et al.   PROTEIN SCIENCE

Herpesvirus and Autophagy: “All Right, Everybody Be Cool, This Is a Robbery!”

(2017) et al.   Viruses-Basel

Autophagy interaction with herpes simplex virus type-1 infection

(2016) Douglas O'Connell et al.   Autophagy

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons

(2016) Sarah Katzenell et al.   JOURNAL OF VIROLOGY

The mutation significance cutoff: gene-level thresholds for variant predictions

(2016) Yuval Itan et al.   NATURE METHODS

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

(2015) Sujuan Guo et al.   Autophagy

Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis

(2015) N Mørk et al.   GENES AND IMMUNITY

Functional IRF3 deficiency in a patient with herpes simplex encephalitis

(2015) Line Lykke Andersen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Abstract 4291: A novel image-based cytometry method for autophagy detection in living cells

(2015) Leo Li-Ying Chan et al.   CANCER RESEARCH

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies

(2014) Jean-Laurent Casanova et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mollaret's meningitis

(2014) Zaw Min et al.   LANCET INFECTIOUS DISEASES

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Early signalling events of autophagy

(2013) Laura E. Gallagher et al.   Essays in Biochemistry

Autophagy and Viruses: Adversaries or Allies?

(2013) Xiaonan Dong et al.   Journal of Innate Immunity

Herpesviruses: latency and reactivation – viral strategies and host response

(2013) Bjørn Grinde   Journal of Oral Microbiology

Divergent Roles of Autophagy in Virus Infection

(2013) Abhilash Chiramel et al.   Cells

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

(2012) Daniel C Kirouac et al.   BMC Systems Biology

A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex Virus

(2012) Brian Yordy et al.   Cell Host & Microbe

HeterozygousTBK1mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

(2012) Melina Herman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Herpes Simplex Virus 1 Us11 Protein Inhibits Autophagy through Its Interaction with the Protein Kinase PKR

(2012) M. Lussignol et al.   JOURNAL OF VIROLOGY

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

(2011) Vanessa Sancho-Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes

(2011) Simon B. Rasmussen et al.   JOURNAL OF IMMUNOLOGY

Early Induction of Autophagy in Human Fibroblasts after Infection with Human Cytomegalovirus or Herpes Simplex Virus 1

(2011) S. McFarlane et al.   JOURNAL OF VIROLOGY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

(2010) Anthony Orvedahl et al.   Cell Host & Microbe

Human TRAF3 Adaptor Molecule Deficiency Leads to Impaired Toll-like Receptor 3 Response and Susceptibility to Herpes Simplex Encephalitis

(2010) Rebeca Pérez de Diego et al.   IMMUNITY

Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model

(2009) Maria Jakobsen et al.   MOLECULAR THERAPY

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE