A Scalable Approach Reveals Functional Responses of iPSC Cardiomyocyte 3D Spheroids

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

(2020) Elisa Giacomelli et al.   Cell Stem Cell

Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes

(2018) L.G.J. Tertoolen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes

(2018) Bärbel M. Ulmer et al.   Stem Cell Reports

Characterization and Validation of a Human 3D Cardiac Microtissue for the Assessment of Changes in Cardiac Pathology

(2018) Caroline R. Archer et al.   Scientific Reports

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

(2017) Richard J. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac spheroids as promising in vitro models to study the human heart microenvironment

(2017) Liudmila Polonchuk et al.   Scientific Reports

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac TissueClinical Perspective

(2016) Jia-Ling Ruan et al.   CIRCULATION

Extracellular Matrix–Mediated Maturation of Human Pluripotent Stem Cell–Derived Cardiac Monolayer Structure and Electrophysiological Function

(2016) Todd J. Herron et al.   Circulation-Arrhythmia and Electrophysiology

From the Cover: High-Throughput Imaging of Cardiac Microtissues for the Assessment of Cardiac Contraction during Drug Discovery

(2016) Amy Pointon et al.   TOXICOLOGICAL SCIENCES

OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology

(2016) Aleksandra Klimas et al.   Nature Communications

Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes

(2016) George Eng et al.   Nature Communications

Human Engineered Heart Tissue: Analysis of Contractile Force

(2016) Ingra Mannhardt et al.   Stem Cell Reports

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes

(2015) Andrea M. Isidori et al.   CARDIOVASCULAR RESEARCH

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes

(2015) Philippe Beauchamp et al.   TISSUE ENGINEERING PART C-METHODS

An integrated platform for simultaneous multi-well field potential recording and Fura-2-based calcium transient ratiometry in human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes

(2015) Georg Rast et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation

(2014) Marc N. Hirt et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function

(2014) Alexandra Traister et al.   Nature Communications

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes

(2013) Donghui Zhang et al.   BIOMATERIALS

Mechanism-Based Facilitated Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes

(2013) Deborah K. Lieu et al.   Circulation-Arrhythmia and Electrophysiology

Electronic “expression” of the inward rectifier in cardiocytes derived from human-induced pluripotent stem cells

(2013) Glenna C.L. Bett et al.   HEART RHYTHM

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

(2013) Sara S Nunes et al.   NATURE METHODS

A Novel 3D Label-Free Monitoring System of hES-Derived Cardiomyocyte Clusters: A Step Forward to In Vitro Cardiotoxicity Testing

(2013) Heinz-Georg Jahnke et al.   PLoS One

Micropatterned co-culture of hepatocyte spheroids layered on non-parenchymal cells to understand heterotypic cellular interactions

(2013) Hidenori Otsuka et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Functional scaffold-free 3-D cardiac microtissues: a novel model for the investigation of heart cells

(2012) B. R. Desroches et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Evaluation of Human MRC-5 Cells as a Feeder Layer in a Xenobiotic-Free Culture System for Conjunctival Epithelial Progenitor Cells

(2012) Stefan Schrader et al.   CURRENT EYE RESEARCH

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG

(2012) Malin K.B. Jonsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of Human Fibroblast Cell Lines as a Feeder Layer for Human Corneal Epithelial Regeneration

(2012) Rong Lu et al.   PLoS One

Maximum Diastolic Potential of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Depends Critically on IKr

(2012) Michael Xavier Doss et al.   PLoS One

Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function

(2011) Brian Liau et al.   BIOMATERIALS

Human Cardiac Stem Cell Differentiation Is Regulated by a Mircrine Mechanism

(2011) Toru Hosoda et al.   CIRCULATION

Stimulating Cardiac Muscle by Light

(2011) Zhiheng Jia et al.   Circulation-Arrhythmia and Electrophysiology

Three-dimensional tissue culture based on magnetic cell levitation

(2010) Glauco R. Souza et al.   Nature Nanotechnology