Extracellular milieu grossly alters pathogen-specific immune response of mammary epithelial cells

Rapid Temporal Dynamics of Transcription, Protein Synthesis, and Secretion during Macrophage Activation

(2014) Katrin Eichelbaum et al.   MOLECULAR & CELLULAR PROTEOMICS

Host defence related responses in bovine milk during an experimentally induced Streptococcus uberis infection

(2014) Grant A Smolenski et al.   Proteome Science

What goes up must come down: molecular basis of MAPKAP kinase 2/3-dependent regulation of the inflammatory response and its inhibition

(2013) Matthias Gaestel   BIOLOGICAL CHEMISTRY

Staphylococcus aureus in veterinary medicine

(2013) Vincent Peton et al.   INFECTION GENETICS AND EVOLUTION

Staphylococcus aureus and Escherichia coli elicit different innate immune responses from bovine mammary epithelial cells

(2013) Yunhe Fu et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows

(2012) Juliane Günther et al.   BMC GENOMICS

Serum Starvation Activates NF-κB Through G Protein β2 Subunit-Mediated Signal

(2012) Tomoko Kohno et al.   DNA AND CELL BIOLOGY

NF-κB in immunobiology

(2011) Matthew S Hayden et al.   CELL RESEARCH

Staphylococcus aureus induces IL-1β expression through the activation of MAP kinases and AP-1, CRE and NF-κB transcription factors in the bovine mammary gland epithelial cells

(2011) Kyoung Whun Kim et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

The role of tristetraprolin in cancer and inflammation

(2011) Sandhya Sanduja   Frontiers in Bioscience-Landmark

Genomic and proteomic characterization of Staphylococcus aureus mastitis isolates of bovine origin

(2011) Carmen Wolf et al.   PROTEOMICS

Host-response patterns of intramammary infections in dairy cows

(2011) Ynte H. Schukken et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Muramyl Dipeptide Synergizes with Staphylococcus aureus Lipoteichoic Acid To Recruit Neutrophils in the Mammary Gland and To Stimulate Mammary Epithelial Cells

(2010) S. Bougarn et al.   Clinical and Vaccine Immunology

Comparative Kinetics ofEscherichia coli- andStaphylococcus aureus-Specific Activation of Key Immune Pathways in Mammary Epithelial Cells Demonstrates ThatS. aureusElicits a Delayed Response Dominated by Interleukin-6 (IL-6) but Not by IL-1A or Tumor Necrosis Factor Alpha

(2010) Juliane Günther et al.   INFECTION AND IMMUNITY

Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells

(2010) H. Tsukamoto et al.   INTERNATIONAL IMMUNOLOGY

Staphylococcal Strains Vary Greatly in Their Ability to Induce an Inflammatory Response in Endothelial Cells

(2010) Matthias Grundmeier et al.   JOURNAL OF INFECTIOUS DISEASES

Proteomics, Genomics, and Pathway Analyses ofEscherichia coliandStaphylococcus aureusInfected Milk Whey Reveal Molecular Pathways and Networks Involved in Mastitis

(2010) Eveline M. Ibeagha-Awemu et al.   JOURNAL OF PROTEOME RESEARCH

The bovine milk proteome: cherishing, nourishing and fostering molecular complexity. An interactomics and functional overview

(2010) Angelo D'Alessandro et al.   Molecular BioSystems

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Expander: from expression microarrays to networks and functions

(2010) Igor Ulitsky et al.   Nature Protocols

Performance of serum-supplemented and serum-free media in IFNγ Elispot Assays for human T cells

(2009) Sylvia Janetzki et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Roles of NF-κB in health and disease: mechanisms and therapeutic potential

(2009) Ee Tsin Wong et al.   CLINICAL SCIENCE

Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle

(2009) B. Griesbeck-Zilch et al.   JOURNAL OF DAIRY SCIENCE

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Targeting innate immunity protein kinase signalling in inflammation

(2009) Matthias Gaestel et al.   NATURE REVIEWS DRUG DISCOVERY

Stimulated expression of TNF-α and IL-8, but not of lingual antimicrobial peptide reflects the concentration of pathogens contacting bovine mammary epithelial cells

(2009) Juliane Günther et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge withEscherichia coli

(2009) Juliane Günther et al.   VETERINARY RESEARCH

Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection

(2008) Ylva Lutzow et al.   BMC Veterinary Research

TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

(2008) Ulrich Zähringer et al.   IMMUNOBIOLOGY

Pathogen-dependent induction of cytokines and other soluble inflammatory mediators during intramammary infection of dairy cows1

(2008) D. D. Bannerman   JOURNAL OF ANIMAL SCIENCE

Staphylococcus aureus and Escherichia coli Cause Deviating Expression Profiles of Cytokines and Lactoferrin Messenger Ribonucleic Acid in Mammary Epithelial Cells

(2008) B. Griesbeck-Zilch et al.   JOURNAL OF DAIRY SCIENCE

Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-κB in mammary epithelial cells and to quickly induce TNFα and interleukin-8 (CXCL8) expression in the udder

(2008) Wei Yang et al.   MOLECULAR IMMUNOLOGY

Escherichia coli, but notStaphylococcus aureustriggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow

(2008) Wolfram Petzl et al.   VETERINARY RESEARCH