CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer

B cells are associated with survival and immunotherapy response in sarcoma

(2020) Florent Petitprez et al.   NATURE

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer

(2019) Mary L. Disis et al.   JAMA Oncology

IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection

(2019) Zhe Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8 + CXCR5 + T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer

(2018) Jifu E et al.   HUMAN IMMUNOLOGY

Accumulation of follicular CD8+ T cells in pathogenic SIV infection

(2018) Sara Ferrando-Martinez et al.   JOURNAL OF CLINICAL INVESTIGATION

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade

(2018) Daniela S. Thommen et al.   NATURE MEDICINE

Suppression of Tcf1 by Inflammatory Cytokines Facilitates Effector CD8 T Cell Differentiation

(2018) Maxime Danilo et al.   Cell Reports

High-dimensional single cell analysis identifies stem-like cytotoxic CD8+T cells infiltrating human tumors

(2018) Jolanda Brummelman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

(2018) Hanjie Li et al.   CELL

CXCR5 + CD8 + T cells potently infiltrate pancreatic tumors and present high functionality

(2017) Minghui Bai et al.   EXPERIMENTAL CELL RESEARCH

Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

(2017) Kevin Man et al.   IMMUNITY

CXCR5 + CD8 + T cells could induce the death of tumor cells in HBV-related hepatocellular carcinoma

(2017) Yun Jin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tumor-Infiltrating Plasma Cells Are Associated with Tertiary Lymphoid Structures, Cytolytic T-Cell Responses, and Superior Prognosis in Ovarian Cancer

(2016) D. R. Kroeger et al.   CLINICAL CANCER RESEARCH

T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections

(2016) Daniel T. Utzschneider et al.   IMMUNITY

Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection

(2016) Ran He et al.   NATURE

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy

(2016) Se Jin Im et al.   NATURE

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

(2016) Yew Ann Leong et al.   NATURE IMMUNOLOGY

CXCL13 is a plasma biomarker of germinal center activity

(2016) Colin Havenar-Daughton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer

(2016) Sebastian Lundgren et al.   Journal of Ovarian Research

CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer

(2016) Katelyn T. Byrne et al.   Cell Reports

IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs

(2015) Francesca Barone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCL13 Production in B Cells via Toll-like Receptor/Lymphotoxin Receptor Signaling Is Involved in Lymphoid Neogenesis in Chronic Obstructive Pulmonary Disease

(2013) Eleni Litsiou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

CD4+ follicular helper T cell infiltration predicts breast cancer survival

(2013) Chunyan Gu-Trantien et al.   JOURNAL OF CLINICAL INVESTIGATION

CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27- Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer

(2012) J. S. Nielsen et al.   CLINICAL CANCER RESEARCH

Inhibition of follicular T-helper cells by CD8+ regulatory T cells is essential for self tolerance

(2010) Hye-Jung Kim et al.   NATURE