Termini restraining of small membrane proteins enables structure determination at near-atomic resolution

Protein Disulfide Exchange by the Intramembrane Enzymes DsbB, DsbD, and CcdA

(2020) John H. Bushweller   JOURNAL OF MOLECULAR BIOLOGY

Structural insights into tetraspanin CD9 function

(2020) Rie Umeda et al.   Nature Communications

Open conformation of tetraspanins shapes interaction partner networks on cell membranes

(2020) Yihu Yang et al.   EMBO JOURNAL

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

(2019) Jonathan J. Ruprecht et al.   CELL

Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown

(2019) Alex J. Vecchio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitroreconstitution, functional dissection, and mutational analysis of metal ion transport by mitoferrin-1

(2018) Eric T. Christenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acyl recognition and transfer by an integral membraneS-acyltransferase

(2018) Mitra S. Rana et al.   SCIENCE

Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

(2016) Brandon Zimmerman et al.   CELL

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies

(2016) Francesca Magnani et al.   Nature Protocols

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer

(2016) Guomin Shen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer

(2016) Guomin Shen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for disruption of claudin assembly in tight junctions by an enterotoxin

(2016) Takehiro Shinoda et al.   Scientific Reports

Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria

(2015) Cristina Landeta et al.   Nature Chemical Biology

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate

(2015) Hui Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate

(2015) Hui Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane topology of transmembrane proteins: determinants and experimental tools

(2014) Hunsang Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tetraspanins at a glance

(2014) S. Charrin et al.   JOURNAL OF CELL SCIENCE

Quality Control in Eukaryotic Membrane Protein Overproduction

(2014) Jennifer A. Thomas et al.   JOURNAL OF MOLECULAR BIOLOGY

Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter

(2014) JungMin Kim et al.   NATURE

JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia

(2014) Kaan Boztug et al.   NATURE GENETICS

Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer

(2014) Shixuan Liu et al.   Nature Communications

Breaking the barriers in membrane protein crystallography

(2013) Hae Joo Kang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells

(2013) J.-K. Tie et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors

(2012) Eugene Chun et al.   STRUCTURE

A Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Protein Precrystallization Screening

(2012) Motoyuki Hattori et al.   STRUCTURE

A crystal clear solution for determining G-protein-coupled receptor structures

(2012) Christopher G. Tate   TRENDS IN BIOCHEMICAL SCIENCES

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Lipidic cubic phase technologies for membrane protein structural studies

(2011) Vadim Cherezov   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cross-Crystal Averaging with Search Models to Improve Molecular Replacement Phases

(2011) Weikai Li et al.   STRUCTURE

Recent developments in classical density modification

(2010) Kevin Cowtan   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of a bacterial homologue of vitamin K epoxide reductase

(2010) Weikai Li et al.   NATURE

Genome-wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms

(2010) Erik Wallin et al.   PROTEIN SCIENCE

Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB

(2009) Kenji Inaba et al.   EMBO JOURNAL

Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin

(2009) R. J. Dutton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation

(2008) Yunpeng Zhou et al.   MOLECULAR CELL

Conformational thermostabilization of the  1-adrenergic receptor in a detergent-resistant form

(2008) M. J. Serrano-Vega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microscale Fluorescent Thermal Stability Assay for Membrane Proteins

(2008) Alexander I. Alexandrov et al.   STRUCTURE

The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases

(2005) Carolyn S. Sevier et al.   PROTEIN SCIENCE