Coexpression of MmpS5 and MmpL5 Contributes to Both Efflux Transporter MmpL5 Trimerization and Drug Resistance in Mycobacterium tuberculosis

Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target

(2019) Bing Zhang et al.   CELL

Altered Mycobacterium tuberculosis Cell Wall Metabolism and Physiology Associated With RpoB Mutation H526D

(2018) Victoria L. Campodónico et al.   Frontiers in Microbiology

Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus

(2018) Matthias Richard et al.   Frontiers in Microbiology

Mycobacterial Cell Wall Synthesis Inhibitors Cause Lethal ATP Burst

(2018) Annanya Shetty et al.   Frontiers in Microbiology

Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus

(2018) Matthias Richard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The diverse family of MmpL transporters in mycobacteria: from regulation to antimicrobial developments

(2017) Albertus Viljoen et al.   MOLECULAR MICROBIOLOGY

MmpS5/MmpL5 as an efflux pump in Mycobacterium species

(2017) Julien Briffotaux et al.   TUBERCULOSIS

MmpL transporter-mediated export of cell-wall associated lipids and siderophores in mycobacteria

(2016) Christian Chalut   TUBERCULOSIS

Substrate-dependent dynamics of the multidrug efflux transporter AcrB of Escherichia coli

(2016) Kentaro Yamamoto et al.   Scientific Reports

Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis

(2015) Yu-Min Chuang et al.   mBio

Cross-Resistance between Clofazimine and Bedaquiline through Upregulation of MmpL5 in Mycobacterium tuberculosis

(2014) R. C. Hartkoorn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structure of the Transcriptional Regulator Rv0678 ofMycobacterium tuberculosis

(2014) Abhijith Radhakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis and Translocation of Unsulfated Acyltrehaloses inMycobacterium tuberculosis

(2014) Juan Manuel Belardinelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Verapamil, and Its Metabolite Norverapamil, Inhibit Macrophage-induced, Bacterial Efflux Pump-mediated Tolerance to Multiple Anti-tubercular Drugs

(2014) Kristin N. Adams et al.   JOURNAL OF INFECTIOUS DISEASES

Impact of osmotic stress on protein diffusion inLactococcus lactis

(2014) Jacek T. Mika et al.   MOLECULAR MICROBIOLOGY

Structure of the AcrAB–TolC multidrug efflux pump

(2014) Dijun Du et al.   NATURE

Acquired Resistance of Mycobacterium tuberculosis to Bedaquiline

(2014) Koen Andries et al.   PLoS One

MmpL11 Protein Transports Mycolic Acid-containing Lipids to the Mycobacterial Cell Wall and Contributes to Biofilm Formation in Mycobacterium smegmatis

(2013) Sophia A. Pacheco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis

(2013) Thomas R. Ioerger et al.   PLoS One

Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

(2013) Ryan M. Wells et al.   PLoS Pathogens

Mutation Analysis of MycobacterialrpoBGenes and Rifampin Resistance Using Recombinant Mycobacterium smegmatis

(2012) Noboru Nakata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria

(2012) Cristian Varela et al.   CHEMISTRY & BIOLOGY

Mutation Analysis of theMycobacterium leprae folP1Gene and Dapsone Resistance

(2010) Noboru Nakata et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mobility of Cytoplasmic, Membrane, and DNA-Binding Proteins in Escherichia coli

(2010) Mohit Kumar et al.   BIOPHYSICAL JOURNAL

MmpS4 promotes glycopeptidolipids biosynthesis and export in Mycobacterium smegmatis

(2010) Caroline Deshayes et al.   MOLECULAR MICROBIOLOGY

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

Efflux-Mediated Drug Resistance in Bacteria

(2009) Xian-Zhi Li et al.   DRUGS

Direct Visualization of the Outer Membrane of Mycobacteria and Corynebacteria in Their Native State

(2008) B. Zuber et al.   JOURNAL OF BACTERIOLOGY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols

Disclosure of the mycobacterial outer membrane: Cryo-electron tomography and vitreous sections reveal the lipid bilayer structure

(2008) C. Hoffmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system

(2008) Anna Milano et al.   TUBERCULOSIS