Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain

Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet

(2019) Domenico Sergi et al.   Frontiers in Physiology

“Hypothalamic Microinflammation” Paradigm in Aging and Metabolic Diseases

(2019) Dongsheng Cai et al.   Cell Metabolism

Short-term high-fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity

(2017) E. Balland et al.   JOURNAL OF NEUROENDOCRINOLOGY

High-fat diet-induced obesity and insulin resistance are characterized by differential beta oscillatory signaling of the limbic cortico-basal ganglia loop

(2017) Lukas Maurer et al.   Scientific Reports

iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents

(2017) Carlos Kiyoshi Katashima et al.   Scientific Reports

Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action

(2017) Beatrice M. Filippi et al.   Cell Reports

UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness

(2016) Chitoku Toda et al.   CELL

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding

(2015) Marcelo O. Dietrich et al.   CELL

Increased Oxidative Stress and Mitochondrial Dysfunction in Zucker Diabetic Rat Liver and Brain

(2015) Haider Raza et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Disruption of mitochondrial fission in the liver protects mice from diet-induced obesity and metabolic deterioration

(2015) Lixiang Wang et al.   DIABETOLOGIA

Obesity accelerates cognitive decline by aggravating mitochondrial dysfunction, insulin resistance and synaptic dysfunction under estrogen-deprived conditions

(2015) Wasana Pratchayasakul et al.   HORMONES AND BEHAVIOR

Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network

(2015) Clémence D Côté et al.   NATURE MEDICINE

S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction

(2015) L. Yang et al.   SCIENCE

Glial fibrillary acidic protein: from intermediate filament assembly and gliosis to neurobiomarker

(2015) Zhihui Yang et al.   TRENDS IN NEUROSCIENCES

Muscle-specific Drp1 overexpression impairs skeletal muscle growth via translational attenuation

(2015) T Touvier et al.   Cell Death & Disease

A fatty acid-dependent hypothalamic–DVC neurocircuitry that regulates hepatic secretion of triglyceride-rich lipoproteins

(2015) Jessica T. Y. Yue et al.   Nature Communications

An optimized method for high-titer lentivirus preparations without ultracentrifugation

(2015) Wei Jiang et al.   Scientific Reports

Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice

(2015) Laura B. Buckman et al.   Molecular Metabolism

Measurement of NO in biological samples

(2014) C Csonka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intranasal Insulin Suppresses Endogenous Glucose Production in Humans Compared With Placebo in the Presence of Similar Venous Insulin Concentrations

(2014) Satya Dash et al.   DIABETES

Mitochondrial response to nutrient availability and its role in metabolic disease

(2014) A. W. Gao et al.   EMBO Molecular Medicine

Mitochondrial dynamics in the central regulation of metabolism

(2014) Carole M. Nasrallah et al.   Nature Reviews Endocrinology

Mitochondrial Dynamics Controlled by Mitofusins Regulate Agrp Neuronal Activity and Diet-Induced Obesity

(2013) Marcelo O. Dietrich et al.   CELL

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

(2013) Marc Schneeberger et al.   CELL

Insulin Signals Through the Dorsal Vagal Complex to Regulate Energy Balance

(2013) B. M. Filippi et al.   DIABETES

Positive Feedback Regulation of Human Inducible Nitric-oxide Synthase Expression by Ras ProteinS-Nitrosylation

(2013) Martin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance

(2013) Marc Schneeberger et al.   JOURNAL OF ENDOCRINOLOGY

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

Insulin Activates Erk1/2 Signaling in the Dorsal Vagal Complex to Inhibit Glucose Production

(2012) Beatrice M. Filippi et al.   Cell Metabolism

DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption

(2012) Noppamas Pipatpiboon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuroinflammation and neurodegeneration in overnutrition-induced diseases

(2012) Dongsheng Cai   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Influence of the Hepatic Eukaryotic Initiation Factor 2α (eIF2α) Endoplasmic Reticulum (ER) Stress Response Pathway on Insulin-mediated ER Stress and Hepatic and Peripheral Glucose Metabolism

(2011) Andreas L. Birkenfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Quantification of S-Nitrosylation by Cysteine Reactive Tandem Mass Tag Switch Assay

(2011) Christopher I. Murray et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle

(2011) H.-F. Jheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial energy metabolism and ageing

(2010) Ivana Bratic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

S-Nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration

(2010) Tomohiro Nakamura et al.   MITOCHONDRION

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of NOS and nitrotyrosine expression in the rat striatum following experimental hepatic encephalopathy

(2009) Isabel Suárez et al.   METABOLIC BRAIN DISEASE

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Nitric Oxide–mediated Modulation of Synaptic Activity by Astrocytic P2Y Receptors

(2008) Bhupesh Mehta et al.   JOURNAL OF GENERAL PHYSIOLOGY