Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia

Wip1 regulates Smad4 phosphorylation and inhibits TGF ‐β signaling

(2020) Dong‐Seok Park et al.   EMBO REPORTS

Age-related changes in the gut microbiota influence systemic inflammation and stroke outcome

(2018) Monica S. Spychala et al.   ANNALS OF NEUROLOGY

The imidazoline I 2 receptor agonist 2-BFI attenuates hypersensitivity and spinal neuroinflammation in a rat model of neuropathic pain

(2018) Justin N. Siemian et al.   BIOCHEMICAL PHARMACOLOGY

NF-κB-induced WIP1 expression promotes colorectal cancer cell proliferation through mTOR signaling

(2018) Fei Bai et al.   BIOMEDICINE & PHARMACOTHERAPY

Wip1 regulates blood-brain barrier function and neuro-inflammation induced by lipopolysaccharide via the sonic hedgehog signaling signaling pathway

(2018) Hong Zhen et al.   MOLECULAR IMMUNOLOGY

Wip1 knockout inhibits neurogenesis by affecting the Wnt/β-catenin signaling pathway in focal cerebral ischemia in mice

(2018) Cai-Wei Qiu et al.   EXPERIMENTAL NEUROLOGY

Transcriptome evidence reveals enhanced autophagy-lysosomal function in centenarians

(2018) Fu-Hui Xiao et al.   GENOME RESEARCH

A new mechanism of inhibition of IL-1β secretion by celastrol through the NLRP3 inflammasome pathway

(2017) Wenyu Xin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction of Wip1 and NF-κB regulates neuroinflammatory response in astrocytes

(2017) Fan Xu et al.   INFLAMMATION RESEARCH

Transcriptional control of microglia phenotypes in health and disease

(2017) Inge R. Holtman et al.   JOURNAL OF CLINICAL INVESTIGATION

WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation

(2017) Dahu Li et al.   Neuroscience Bulletin

Phosphatase Wip1 in Immunity: An Overview and Update

(2017) Xiao-Fei Shen et al.   Frontiers in Immunology

Microglial Physiology and Pathophysiology: Insights from Genome-wide Transcriptional Profiling

(2016) Andrea Crotti et al.   IMMUNITY

Up-regulation of Wip1 involves in neuroinflammation of retinal astrocytes after optic nerve crush via NF-κB signaling pathway

(2016) Haibin Zhong et al.   INFLAMMATION RESEARCH

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

Interleukin-4 Is Essential for Microglia/Macrophage M2 Polarization and Long-Term Recovery After Cerebral Ischemia

(2016) Xiangrong Liu et al.   STROKE

Resveratrol Ameliorates Diabetes-Induced Cardiac Dysfunction Through AT1R-ERK/p38 MAPK Signaling Pathway

(2015) Yonglin Gao et al.   Cardiovascular Toxicology

Wip1-Deficient Neutrophils Significantly Promote Intestinal Ischemia/Reperfusion Injury in Mice

(2015) J. Du et al.   CURRENT MOLECULAR MEDICINE

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study

(2015) Valery L. Feigin et al.   NEUROEPIDEMIOLOGY

MicroRNA-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin

(2015) Creed M. Stary et al.   STROKE

Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis

(2015) Xia Ma et al.   TOXICOLOGY LETTERS

Regulation of Neuroinflammation through Programed Death-1/Programed Death Ligand Signaling in Neurological Disorders

(2014) Shangfeng Zhao et al.   Frontiers in Cellular Neuroscience

Preventive Effect of Total Flavones of Choerospondias axillaries on Ischemia/Reperfusion-Induced Myocardial Infarction-Related MAPK Signaling Pathway

(2013) Chunmei Li et al.   Cardiovascular Toxicology

Neuroprotective effect of hydroxysafflor yellow A on 6-hydroxydopamine-induced Parkinson's disease in rats

(2013) Bing Han et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Targeted mutation of Fas ligand gene attenuates brain inflammation in experimental stroke

(2011) Feng-nan Niu et al.   BRAIN BEHAVIOR AND IMMUNITY

Anti-inflammatory effects of sophocarpine in LPS-induced RAW 264.7 cells via NF-κB and MAPKs signaling pathways

(2011) Yonglin Gao et al.   TOXICOLOGY IN VITRO