Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis

Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells

(2020) Bernadette A. Chua et al.   Cell Stem Cell

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation

(2020) Anindita Basak et al.   NATURE GENETICS

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

(2020) Lorena Hidalgo San Jose et al.   Cell Reports

Hematopoietic stem cell regulation by the proteostasis network

(2020) Bernadette A. Chua et al.   CURRENT OPINION IN HEMATOLOGY

Cell-type-specific quantification of protein synthesis in vivo

(2019) Lorena Hidalgo San Jose et al.   Nature Protocols

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

(2018) Rajiv K. Khajuria et al.   CELL

The Genetic Landscape of Diamond-Blackfan Anemia

(2018) Jacob C. Ulirsch et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation

(2017) Xin Liu et al.   NATURE CELL BIOLOGY

Ribosomopathies: There’s strength in numbers

(2017) Eric W. Mills et al.   SCIENCE

Bile Acids Protect Expanding Hematopoietic Stem Cells from Unfolded Protein Stress in Fetal Liver

(2016) Valgardur Sigurdsson et al.   Cell Stem Cell

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

(2016) Robert A.J. Signer et al.   GENES & DEVELOPMENT

Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells

(2015) Xiongwei Cai et al.   Cell Stem Cell

Diverse diseases from a ubiquitous process: The ribosomopathy paradox

(2014) Joy Armistead et al.   FEBS LETTERS

Haematopoietic stem cells require a highly regulated protein synthesis rate

(2014) Robert A. J. Signer et al.   NATURE

Altered translation of GATA1 in Diamond-Blackfan anemia

(2014) Leif S Ludwig et al.   NATURE MEDICINE

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How I treat Diamond-Blackfan anemia

(2010) A. Vlachos et al.   BLOOD

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

Congenital Disorders of Ribosome Biogenesis and Bone Marrow Failure

(2009) Kathleen M. Sakamoto et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION