Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic‐like behaviors due to Scn2a haploinsufficiency
出版年份 2021 全文链接
标题
Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic‐like behaviors due to
Scn2a
haploinsufficiency
作者
关键词
-
出版物
Brain and Behavior
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2021-01-23
DOI
10.1002/brb3.2041
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Clinical Spectrum of KCNA1 Mutations: New Insights into Episodic Ataxia and Epilepsy Comorbidity
- (2020) Kelsey Paulhus et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Scn2a haploinsufficient mice display a spectrum of phenotypes affecting anxiety, sociability, memory flexibility and ampakine CX516 rescues their hyperactivity
- (2019) Tetsuya Tatsukawa et al. Molecular Autism
- Cardiorespiratory profiling reveals primary breathing dysfunction in Kcna1-null mice: Implications for sudden unexpected death in epilepsy
- (2019) Hemangini Dhaibar et al. NEUROBIOLOGY OF DISEASE
- The Autism-Associated Gene Scn2a Contributes to Dendritic Excitability and Synaptic Function in the Prefrontal Cortex
- (2019) Perry W.E. Spratt et al. NEURON
- Complete loss of KCNA1 activity causes neonatal epileptic encephalopathy and dyskinesia
- (2019) Edgard Verdura et al. JOURNAL OF MEDICAL GENETICS
- NaV1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age
- (2019) Isabelle Léna et al. Scientific Reports
- Development-related aberrations in Kv1.1 α-subunit exert disruptive effects on bioelectrical activities of neurons in a mouse model of fragile X syndrome
- (2018) Pingping Zhu et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Progress in Understanding and Treating SCN2A -Mediated Disorders
- (2018) Stephan J. Sanders et al. TRENDS IN NEUROSCIENCES
- De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants
- (2018) Amanda Rogers et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Scn2a deletion improves survival and brain–heart dynamics in the Kcna1-null mouse model of sudden unexpected death in epilepsy (SUDEP)
- (2017) Vikas Mishra et al. HUMAN MOLECULAR GENETICS
- Autism spectrum disorder and epileptic encephalopathy: common causes, many questions
- (2017) Siddharth Srivastava et al. Journal of Neurodevelopmental Disorders
- The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms
- (2017) Maël Duménieu et al. Frontiers in Cellular Neuroscience
- Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder
- (2016) Hyopil Kim et al. Behavioral and Brain Functions
- Epileptic encephalopathy: Use and misuse of a clinically and conceptually important concept
- (2016) Katherine B. Howell et al. EPILEPSIA
- Adult restoration of Shank3 expression rescues selective autistic-like phenotypes
- (2016) Yuan Mei et al. NATURE
- Advancing the understanding of autism disease mechanisms through genetics
- (2016) Luis de la Torre-Ubieta et al. NATURE MEDICINE
- Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice
- (2016) Harrison M. Roundtree et al. SLEEP
- Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice
- (2016) Harrison M. Roundtree et al. SLEEP
- The Cognitive and Behavioral Phenotype of the 16p11.2 Deletion in a Clinically Ascertained Population
- (2015) Ellen Hanson et al. BIOLOGICAL PSYCHIATRY
- Behavioral changes following a single episode of early-life seizures support the latent development of an autistic phenotype
- (2015) Paul B. Bernard et al. EPILEPSY & BEHAVIOR
- Autism Spectrum Disorder and Epilepsy
- (2015) Shafali Spurling Jeste et al. JOURNAL OF CHILD NEUROLOGY
- Excess of rare, inherited truncating mutations in autism
- (2015) Niklas Krumm et al. NATURE GENETICS
- Pathway-driven discovery of epilepsy genes
- (2015) Jeffrey Noebels NATURE NEUROSCIENCE
- Head circumference and brain size in autism spectrum disorder: A systematic review and meta-analysis
- (2015) Roberto Sacco et al. PSYCHIATRY RESEARCH-NEUROIMAGING
- Seizures and Epilepsy: An Overview for Neuroscientists
- (2015) C. E. Stafstrom et al. Cold Spring Harbor Perspectives in Medicine
- Molecular identity of axonal sodium channels in human cortical pyramidal cells
- (2014) Cuiping Tian et al. Frontiers in Cellular Neuroscience
- Action Potential Initiation in Neocortical Inhibitory Interneurons
- (2014) Tun Li et al. PLOS BIOLOGY
- Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy
- (2013) J. K. Holth et al. JOURNAL OF NEUROSCIENCE
- Drug discovery for autism spectrum disorder: challenges and opportunities
- (2013) Anirvan Ghosh et al. NATURE REVIEWS DRUG DISCOVERY
- Autism-related behavioral abnormalities in synapsin knockout mice
- (2012) Barbara Greco et al. BEHAVIOURAL BRAIN RESEARCH
- Consensus Paper: Pathological Role of the Cerebellum in Autism
- (2012) S. Hossein Fatemi et al. CEREBELLUM
- Genetic architecture in autism spectrum disorder
- (2012) Bernie Devlin et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Routine developmental and autism screening in an epilepsy care setting
- (2012) Breanne Fisher et al. EPILEPSY & BEHAVIOR
- De novo mutations revealed by whole-exome sequencing are strongly associated with autism
- (2012) Stephan J. Sanders et al. NATURE
- Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice
- (2012) Aubin Michalon et al. NEURON
- Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism
- (2012) J. L. Silverman et al. Science Translational Medicine
- Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders
- (2012) Will Spooren et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders
- (2012) Claire S. Leblond et al. PLoS Genetics
- Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy
- (2011) Tara Klassen et al. CELL
- Cell-Type-Dependent Molecular Composition of the Axon Initial Segment
- (2009) A. Lorincz et al. JOURNAL OF NEUROSCIENCE
- Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation
- (2009) Wenqin Hu et al. NATURE NEUROSCIENCE
- Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP
- (2009) Jill L Silverman et al. NEUROPSYCHOPHARMACOLOGY
- Sleep problems in autism spectrum disorders: Prevalence, nature, & possible biopsychosocial aetiologies
- (2009) Amanda L. Richdale et al. SLEEP MEDICINE REVIEWS
- Reversal of learning deficits in a Tsc2 +/− mouse model of tuberous sclerosis
- (2008) Dan Ehninger et al. NATURE MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started