期刊
MICROMACHINES
卷 12, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/mi12020108
关键词
IOP; glaucoma; wearable; strain gauge; MEMS; high sensitivity
类别
资金
- National Natural Science Foundation of China [61634006, 61671424]
- National Key Technologies RD Program [2017YFA0205903, 2017YFA0701100, 2016YFB0402405, 2016YFB0401303]
- strategic priority research program of CAS pilot project [XDB32030100, XDB32040200]
- Key Research Program of Frontier Science, CAS [QYZDY-SSWJSC004]
- CAS pilot project [XDA16020902]
- Beijing ST planning task [Z161100002616019]
The study focuses on a wearable contact lens IOP sensor based on a platinum strain gauge for continuous monitoring of intraocular pressure (IOP). The sensor demonstrated high sensitivity, excellent dynamic cycling performance, and satisfactory stability in tests on an eyeball model. It shows promise for potential applications in continuous IOP monitoring.
Intraocular pressure (IOP) is an essential indicator of the diagnosis and treatment of glaucoma. IOP has an apparent physiological rhythm, and it often reaches its peak value at night. To avoid missing the peak value at night and sample the entire rhythm cycle, the continuous monitoring of IOP is urgently needed. A wearable contact lens IOP sensor based on a platinum (Pt) strain gauge is fabricated by the micro-electro-mechanical (MEMS) process. The structure and parameters of the strain gauge are optimized to improve the sensitivity and temperature stability. Tests on an eyeball model indicate that the IOP sensor has a high sensitivity of 289.5 mu V/mmHg and excellent dynamic cycling performance at different speeds of IOP variation. The temperature drift coefficient of the sensor is 33.4 mu V/degrees C. The non-invasive IOP sensor proposed in this report exhibits high sensitivity and satisfactory stability, promising a potential in continuous IOP monitoring.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据