标题
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
作者
关键词
SARS CoV 2, Monocytes, Viral replication, Lipid metabolism, Inflammation, Respiratory infections, COVID 19, Biosynthesis
出版物
PLoS Pathogens
Volume 16, Issue 12, Pages e1009127
出版商
Public Library of Science (PLoS)
发表日期
2020-12-17
DOI
10.1371/journal.ppat.1009127
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- A pneumonia outbreak associated with a new coronavirus of probable bat origin
- (2020) Peng Zhou et al. NATURE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
- (2020) Bo Shen et al. CELL
- The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
- (2020) Francesca Coperchini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- The proximal origin of SARS-CoV-2
- (2020) Kristian G. Andersen et al. NATURE MEDICINE
- Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis
- (2020) Ana Campos Codo et al. Cell Metabolism
- SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target
- (2019) Shuofeng Yuan et al. Nature Communications
- Fat, fight, and beyond: The multiple roles of lipid droplets in infections and inflammation
- (2019) Filipe S. Pereira‐Dutra et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication
- (2019) Orly Laufman et al. CELL
- Spatiotemporal Coupling of the Hepatitis C Virus Replication Cycle by Creating a Lipid Droplet- Proximal Membranous Replication Compartment
- (2019) Ji-Young Lee et al. Cell Reports
- Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles
- (2018) Ekaterina G. Viktorova et al. PLoS Pathogens
- Membrane alterations induced by nonstructural proteins of human norovirus
- (2017) Sylvie Y. Doerflinger et al. PLoS Pathogens
- Modulation of Lipid Droplet Metabolism—A Potential Target for Therapeutic Intervention in Flaviviridae Infections
- (2017) Jingshu Zhang et al. Frontiers in Microbiology
- Rotavirus replication and the role of cellular lipid droplets: New therapeutic targets?
- (2016) Andrew Lever et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Low impact to fixed cell processing aiming transmission electron microscopy
- (2016) Ortrud Monika Barth et al. MEMORIAS DO INSTITUTO OSWALDO CRUZ
- Lipid droplets form complexes with viroplasms and are crucial for rotavirus replication
- (2016) Sue E Crawford et al. Current Opinion in Virology
- CD36 is a co-receptor for hepatitis C virus E1 protein attachment
- (2016) Jun-Jun Cheng et al. Scientific Reports
- Targeting host lipid synthesis and metabolism to inhibit dengue and hepatitis C viruses
- (2015) Valerie A. Villareal et al. ANTIVIRAL RESEARCH
- Hepatitis C virus and lipid droplets: finding a niche
- (2015) Ana Filipe et al. TRENDS IN MOLECULAR MEDICINE
- Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside--Caught in the Web
- (2014) L. Chatel-Chaix et al. JOURNAL OF VIROLOGY
- Cytokine and Chemokine Profiles in Lung Tissues from Fatal Cases of 2009 Pandemic Influenza A (H1N1)
- (2013) Rongbao Gao et al. AMERICAN JOURNAL OF PATHOLOGY
- Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection
- (2013) Patrícia E. Almeida et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Diacylglycerol Acyltransferase-1 Localizes Hepatitis C Virus NS5A Protein to Lipid Droplets and Enhances NS5A Interaction with the Viral Capsid Core
- (2013) Gregory Camus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells
- (2013) Stefano Berre et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of rotavirus replication by downregulation of fatty acid synthesis
- (2013) E. R. Gaunt et al. JOURNAL OF GENERAL VIROLOGY
- Bidirectional Lipid Droplet Velocities Are Controlled by Differential Binding Strengths of HCV Core DII Protein
- (2013) Rodney K. Lyn et al. PLoS One
- Herpes simplex type 1 activates glycolysis through engagement of the enzyme 6-phosphofructo-1-kinase (PFK-1)
- (2012) Juliana L. Abrantes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Emerging Role of Lipid Droplets in Host/Pathogen Interactions
- (2011) Eva Herker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins
- (2011) F. A. Carvalho et al. JOURNAL OF VIROLOGY
- West Nile Virus Replication Requires Fatty Acid Synthesis but Is Independent on Phosphatidylinositol-4-Phosphate Lipids
- (2011) Miguel A. Martín-Acebes et al. PLoS One
- Lipid body function in eicosanoid synthesis: An update
- (2011) Patricia T. Bozza et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Rotaviruses Associate with Cellular Lipid Droplet Components To Replicate in Viroplasms, and Compounds Disrupting or Blocking Lipid Droplets Inhibit Viroplasm Formation and Viral Replication
- (2010) W. Cheung et al. JOURNAL OF VIROLOGY
- Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
- (2010) Eva Herker et al. NATURE MEDICINE
- Lipid droplets in inflammation and cancer
- (2010) Patricia T. Bozza et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Hepatitis C virus hijacks host lipid metabolism
- (2009) Gulam H. Syed et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation
- (2009) Marcelo M. Samsa et al. PLoS Pathogens
- Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production
- (2008) Wei Yang et al. HEPATOLOGY
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
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