Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

HIV-1 uncoats in the nucleus near sites of integration

(2020) Ryan C. Burdick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus

(2020) Adarsh Dharan et al.   Nature Microbiology

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

(2020) Ashwanth C. Francis et al.   Nature Communications

Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR

(2020) Manman Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the Nuclear Pore Complex

(2019) David Alejandro Bejarano et al.   eLife

Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid

(2018) Jiying Ning et al.   JOURNAL OF VIROLOGY

Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

(2018) Chantal L Márquez et al.   eLife

IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis

(2018) Donna L Mallery et al.   eLife

PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating

(2018) Sanela Rankovic et al.   JOURNAL OF VIROLOGY

Inositol phosphates are assembly co-factors for HIV-1

(2018) Robert A. Dick et al.   NATURE

All-atom virus simulations

(2018) Jodi A Hadden et al.   Current Opinion in Virology

IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating

(2018) Robert Dick et al.   Viruses-Basel

CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations

(2017) Juan R. Perilla et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly

(2017) Sanela Rankovic et al.   JOURNAL OF VIROLOGY

Capsid-Dependent Host Factors in HIV-1 Infection

(2017) Masahiro Yamashita et al.   TRENDS IN MICROBIOLOGY

Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations

(2017) Juan R. Perilla et al.   Nature Communications

All-Atom Molecular Dynamics of Virus Capsids as Drug Targets

(2016) Juan R. Perilla et al.   Journal of Physical Chemistry Letters

HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

(2016) David A. Jacques et al.   NATURE

Analysis of the mechanical properties of wild type and hyperstable mutants of the HIV-1 capsid

(2016) Ruben Ramalho et al.   Retrovirology

The structure and flexibility of conical HIV-1 capsids determined within intact virions

(2016) Simone Mattei et al.   SCIENCE

Molecular Architecture of the Retroviral Capsid

(2016) Juan R. Perilla et al.   TRENDS IN BIOCHEMICAL SCIENCES

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

(2016) Ashwanth C. Francis et al.   PLoS Pathogens

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability

(2015) A. T. Gres et al.   SCIENCE

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

GPU-accelerated analysis and visualization of large structures solved by molecular dynamics flexible fitting

(2014) John E. Stone et al.   FARADAY DISCUSSIONS

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

Generalized scalable multiple copy algorithms for molecular dynamics simulations in NAMD

(2013) Wei Jiang et al.   COMPUTER PHYSICS COMMUNICATIONS

Self-Learning Adaptive Umbrella Sampling Method for the Determination of Free Energy Landscapes in Multiple Dimensions

(2013) Wojciech Wojtas-Niziurski et al.   Journal of Chemical Theory and Computation

Using collective variables to drive molecular dynamics simulations

(2013) Giacomo Fiorin et al.   MOLECULAR PHYSICS

Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics

(2013) Gongpu Zhao et al.   NATURE

Extreme Genetic Fragility of the HIV-1 Capsid

(2013) Suzannah J. Rihn et al.   PLoS Pathogens

Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing

(2012) K. Vanommeslaeghe et al.   Journal of Chemical Information and Modeling

Calculation of Free Energy Landscape in Multi-Dimensions with Hamiltonian-Exchange Umbrella Sampling on Petascale Supercomputer

(2012) Wei Jiang et al.   Journal of Chemical Theory and Computation

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

(2011) A. E. Hulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determinants of the HIV-1 core assembly pathway

(2011) Claudia S. López et al.   VIROLOGY

Matrix Domain Modulates HIV-1 Gag's Nucleic Acid Chaperone Activity via Inositol Phosphate Binding

(2010) C. P. Jones et al.   JOURNAL OF VIROLOGY

Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

(2009) In-Ja L. Byeon et al.   CELL

Molecular dynamics flexible fitting: A practical guide to combine cryo-electron microscopy and X-ray crystallography

(2009) Leonardo G. Trabuco et al.   METHODS