Plant-based vaccines and antibodies to combat COVID-19: current status and prospects

Molecular farming – The slope of enlightenment

(2020) Rainer Fischer et al.   BIOTECHNOLOGY ADVANCES

Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV

(2020) Ming Zheng et al.   Cellular & Molecular Immunology

The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines

(2020) Weilong Shang et al.   npj Vaccines

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

(2020) Alba Grifoni et al.   Cell Host & Microbe

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

(2020) Xiangyu Chen et al.   Cellular & Molecular Immunology

The epidemiology, diagnosis and treatment of COVID-19

(2020) Pan Zhai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

(2020) Chenguang Shen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development

(2020) Cuiqing Ma et al.   MICROBES AND INFECTION

Coronavirus Disease 2019 (COVID-19) Pandemic and Economic Impact

(2020) Tauseef Ahmad et al.   Pakistan Journal of Medical Sciences

Effectiveness of convalescent plasma therapy in severe COVID-19 patients

(2020) Kai Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential Applications of Plant Biotechnology against SARS-CoV-2

(2020) Teresa Capell et al.   TRENDS IN PLANT SCIENCE

COVID-19, an Emerging Coronavirus Infection: Current Scenario and Recent Developments – An Overview

(2020) Alfonso J. Rodriguez-Morales et al.   JOURNAL OF PURE AND APPLIED MICROBIOLOGY

An update on SARS-CoV-2/COVID-19 with particular reference to its clinical pathology, pathogenesis, immunopathology and mitigation strategies

(2020) Kuldeep Dhama et al.   Travel Medicine and Infectious Disease

COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

(2020) Kuldeep Dhama et al.   Human Vaccines & Immunotherapeutics

Current therapies under investigation for COVID-19: potential COVID-19 treatments

(2020) Ellen Weisberg et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

(2020) Qing Ye et al.   JOURNAL OF INFECTION

Plant Solutions for the COVID-19 Pandemic and Beyond: Historical Reflections and Future Perspectives

(2020) Jing-Ke Weng   Molecular Plant

Synergistic antiviral effects against SARS-CoV-2 by plant-based molecules

(2020) Ashish Prasad et al.   PLANT CELL REPORTS

Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection

(2020) Synat Keam et al.   REVIEWS IN MEDICAL VIROLOGY

The socio-economic implications of the coronavirus pandemic (COVID-19): A review

(2020) Maria Nicola et al.   International Journal of Surgery

COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines

(2020) Mohd. Iqbal Yatoo et al.   Human Vaccines & Immunotherapeutics

Plant molecular farming of virus‐like nanoparticles as vaccines and reagents

(2019) Edward P. Rybicki   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant Proteins

(2019) Stefan Schillberg et al.   Frontiers in Plant Science

Edible Vaccines: Promises and Challenges

(2019) Vrinda M Kurup et al.   MOLECULAR BIOTECHNOLOGY

Plant-produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice

(2017) Ming Yang et al.   PLANT BIOTECHNOLOGY JOURNAL

Using transgenic plants and modified plant viruses for the development of treatments for human diseases

(2017) Hwei-San Loh et al.   Current Opinion in Virology

Plant Molecular Pharming for the Treatment of Chronic and Infectious Diseases

(2014) Eva Stoger et al.   Annual Review of Plant Biology

Influenza virus-like particle vaccines made in Nicotiana benthamiana elicit durable, poly-functional and cross-reactive T cell responses to influenza HA antigens

(2014) Nathalie Landry et al.   CLINICAL IMMUNOLOGY

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

(2014) Xiangguo Qiu et al.   NATURE

US signs contract with ZMapp maker to accelerate development of the Ebola drug

(2014) M. McCarthy   BMJ-British Medical Journal

Bioengineering virus-like particles as vaccines

(2013) Linda H.L. Lua et al.   BIOTECHNOLOGY AND BIOENGINEERING

Target Product Selection - Where Can Molecular Pharming Make the Difference?

(2013) Mathew Paul et al.   CURRENT PHARMACEUTICAL DESIGN

Role of plant expression systems in antibody production for passive immunization

(2013) Vikram Virdi et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Safety and immunogenicity of a plant-produced recombinant monomer hemagglutinin-based influenza vaccine derived from influenza A (H1N1)pdm09 virus: A Phase 1 dose-escalation study in healthy adults

(2013) James F. Cummings et al.   VACCINE

Safety and Immunogenicity of a Plant-Produced Recombinant Hemagglutinin-Based Influenza Vaccine (HAI-05) Derived from A/Indonesia/05/2005 (H5N1) Influenza Virus: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study in Healthy Adults

(2012) Jessica Chichester et al.   Viruses-Basel

Emerging antibody products and Nicotiana manufacturing

(2011) Kevin J. Whaley et al.   Human vaccines & immunotherapeutics

Plant-based anti-HIV-1 strategies: vaccine molecules and antiviral approaches

(2010) Nunzia Scotti et al.   Expert Review of Vaccines

Egg-independent vaccine strategies for highly pathogenic H5N1 influenza viruses

(2010) Aseem Pandey et al.   Human vaccines & immunotherapeutics

Success stories in molecular farming-a brief overview

(2010) Loïc Faye et al.   PLANT BIOTECHNOLOGY JOURNAL

The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza

(2010) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Plants as bioreactors for the production of vaccine antigens

(2009) Siddharth Tiwari et al.   BIOTECHNOLOGY ADVANCES

Barley as a green factory for the production of functional Flt3 ligand

(2009) Lýður S. Erlendsson et al.   Biotechnology Journal

The spike protein of SARS-CoV — a target for vaccine and therapeutic development

(2009) Lanying Du et al.   NATURE REVIEWS MICROBIOLOGY

Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice

(2009) Nuoyan Zheng et al.   VACCINE

New horizons in adjuvants for vaccine development

(2008) Steven G. Reed et al.   TRENDS IN IMMUNOLOGY