Article
Food Science & Technology
Maria Kyprianidou, Stavri Chrysostomou, Costas A. Christophi, Konstantinos Giannakou
Summary: This study examines the differences in dietary and lifestyle habits during and after the lockdown measures in Cyprus and finds that the participants had healthier habits during the lockdown period. They consumed more fruits, vegetables, legumes/pulses, fish, and poultry, had higher intake of olive oil, and consumed less alcohol during the lockdown. The study also reveals that there was a higher proportion of participants using delivery services and engaging in physical activity during the lockdown compared to the post-lockdown period.
Article
Public, Environmental & Occupational Health
Nada A. Al-Mulla, Ziyad R. Mahfoud
Summary: This study assessed the impact of quarantine on physical activity, screen time, sleep, and diet in children aged 5 to 12 in Qatar. The results showed that quarantine led to a significant decrease in physical activity, an increase in unhealthy food consumption, and a delay in bedtime and waketime. The majority of parents were disappointed with their child's lifestyle during quarantine. Therefore, interventions should be considered to counteract these negative effects when implementing restrictions.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Ramona De Amicis, Andrea Foppiani, Letizia Galasso, Angela Montaruli, Eliana Roveda, Fabio Esposito, Alberto Battezzati, Simona Bertoli, Alessandro Leone
Summary: During the COVID-19 lockdown, lifestyle deterioration had a negative impact on weight. This cohort study focused on patients undergoing dietary therapy and evaluated the effect of lockdown on weight loss programs, as well as changes in eating habits and chronotype. The study found that well-monitored dietary therapy can maintain weight loss during lockdown, with improvement in eating habits observed. However, the circadian typology also shifted during this period.
Article
Nutrition & Dietetics
Carmen Flores Navarro-Perez, Angel Fernandez-Aparicio, Emilio Gonzalez-Jimenez, Miguel Angel Montero-Alonso, Jacqueline Schmidt-RioValle
Summary: The study found that during the lockdown, the younger population in Andalusia experienced greater changes in physical activity and eating habits, increasing healthier lifestyle choices, indicating their increased awareness on the importance of maintaining good health.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Nasser M. Al-Daghri, Abeer A. Almiman, Kaiser Wani, Malak N. K. Khattak, Naji J. Aljohani, Hanan Alfawaz, Abdulaziz Al-Hameidi, Dara Aldisi, Ghadah Alkhaldi, Shaun Sabico
Summary: This study aimed to evaluate and compare the impact of COVID-19 lockdown on lifestyle changes and related effects in Saudi adults with diabetes mellitus. The findings show that the lockdown had a significant impact on treatment, mental health, physical activity, and dietary habits of individuals with diabetes compared to the control group.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Ana Zaragoza-Marti, Miriam Sanchez-SanSegundo, Rosario Ferrer-Cascales, Eva Maria Gabaldon-Bravo, Ana Laguna-Perez, Lorena Rumbo-Rodriguez
Summary: The study aimed to assess the effects of Mediterranean style-diet before and after COVID-19 confinement on older patients. Participants who adhered to the Mediterranean Diet intervention program before confinement showed improved adherence and maintained nutritional status post-confinement. Although there were no statistically significant differences in BMI between groups before and after confinement, adherence to the Mediterranean Diet may be important in establishing dietary guidelines during confinement situations like COVID-19.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Rosa Casas, Blanca Raido-Quintana, Ana Maria Ruiz-Leon, Sara Castro-Barquero, Isabel Bertomeu, Jordi Gonzalez-Juste, Marta Campolier, Ramon Estruch
Summary: During the COVID-2019 pandemic, Spanish adults had improved dietary habits during home confinement, with higher adherence to the Mediterranean diet. However, negative impacts on physical activity levels, sleep quality, and smoking rates were observed.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Psychology, Multidisciplinary
Anna Lardone, Patrizia Turriziani, Pierpaolo Sorrentino, Onofrio Gigliotta, Andrea Chirico, Fabio Lucidi, Laura Mandolesi
Summary: The study found that during lockdown, the restriction of behaviors resulted in increased non-verbal fluency, as indicated by a significant increase in the number of new drawings. Interestingly, there was a significant tendency to use the left part of each box in the m-FPT, which correlated with TAS-20 and the subscales assessing difficulty in describing and identifying feelings.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Nutrition & Dietetics
Melania Prete, Anna Luzzetti, Livia S. A. Augustin, Giuseppe Porciello, Concetta Montagnese, Ilaria Calabrese, Giada Ballarin, Sergio Coluccia, Linia Patel, Sara Vitale, Elvira Palumbo, Egidio Celentano, Carlo La Vecchia, Anna Crispo
Summary: The lockdown during COVID-19 in Italy led to changes in diet habits, with 67% of people increasing consumption of foods with added sugar. Men and women with low adherence to the Mediterranean Diet were more likely to be physically inactive.
Article
Nutrition & Dietetics
Dorit Hadar-Shoval, Michal Alon-Tirosh, Kfir Asraf, Lubna Tannous-Haddad, Orna Tzischinsky
Summary: Emotional eating poses health risks and COVID-19 related lifestyle changes increase the risk of emotional eating, with gender and COVID-19 related stressors affecting the relationship between lifestyle changes and emotional eating.
Article
Nutrition & Dietetics
Nives Bogataj Jontez, Karin Novak, Sasa Kenig, Ana Petelin, Zala Jenko Praznikar, Nina Mohorko
Summary: This study aimed to investigate the impact of COVID-19-related lockdown on changes in dietary habits, physical activity, and serum markers in healthy adults. Results showed a decrease in diet quality and energy intake during lockdown, as well as lower physical activity levels. Despite no significant changes in body composition, there was a significant increase in serum glucose, total cholesterol, and LDL post-lockdown.
Article
Psychology, Multidisciplinary
Federica Somma, Paolo Bartolomeo, Federica Vallone, Antonietta Argiuolo, Antonio Cerrato, Orazio Miglino, Laura Mandolesi, Maria Clelia Zurlo, Onofrio Gigliotta
Summary: This study investigated the impact of the COVID-19 pandemic on spatial cognition tasks, particularly regarding spatial exploration and pseudoneglect. Results showed an increase in leftward bias and pseudoneglect among participants during the lockdown, which was positively correlated with perceived stress and negatively correlated with positive coping strategies.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Nutrition & Dietetics
Federica Grant, Maria Luisa Scalvedi, Umberto Scognamiglio, Aida Turrini, Laura Rossi
Summary: To limit the spread of coronavirus SARS-CoV-2, a nationwide lockdown started in Italy in March 2020. In this unpredictable situation, a cross-sectional study using an online questionnaire was carried out to evaluate how Italian habits changed during this period, the determinants of changes, and the effect on food waste prevention. The study found that many people in Italy improved the quality of their diet during the lockdown by increasing consumption of fruits, vegetables, legumes, nuts, and fish or shellfish, but also showed unfavorable changes such as excessive consumption of sweets or pastries, comfort foods, and a lack of physical activity. Additionally, the study revealed that respondents with generally high adherence to the Mediterranean Diet improved their eating habits, while those with low adherence remained unchanged, and nearly 80% of respondents were sensitive to food waste.
Article
Multidisciplinary Sciences
Sumbal Shahbaz, Muhammad Zeshan Ashraf, Rubeena Zakar, Florian Fischer, Muhammad Zakria Zakar
Summary: This study utilized a phenomenographic approach to understand the perceptions of Pakistani university students towards COVID-19 and the associated lockdown. The study revealed four main emotional experiences among students: seeking peace, hoping for personal freedom, fearing being a victim of COVID-19, and worrying about their education, future career, and opportunities.
Article
Public, Environmental & Occupational Health
Emma Solomon-Moore, Jeffrey Lambert, Elisabeth Grey, Fiona Gillison, Nick Townsend, Betty Busam, Kyriakos Velemis, Christopher Millen, Fran Baber, Tania Griffin
Summary: This study investigated the diet, physical activity, and mental health status of UK adults during the lockdown and 12 months later. It found that while healthy eating habits worsened, anxiety and mental well-being improved. Parents living with children aged 12-17 may experience increased anxiety.
Editorial Material
Medicine, General & Internal
Arrigo F. G. Cicero, Federica Fogacci, Alessio Bragagni, Claudio Borghi
INTERNAL AND EMERGENCY MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Paolo Palatini, Agostino Virdis, Stefano Masi, Alessandro Mengozzi, Edoardo Casiglia, Valerie Tikhonoff, Arrigo F. G. Cicero, Andrea Ungar, Gianfranco Parati, Giulia Rivasi, Massimo Salvetti, Carlo M. Barbagallo, Michele Bombelli, Raffaella Dell'Oro, Berardino Bruno, Luciano Lippa, Lanfranco D'Elia, Maria Masulli, Paolo Verdecchia, Gianpaolo Reboldi, Fabio Angeli, Francesca Mallamaci, Massimo Cirillo, Marcello Rattazzi, Pietro Cirillo, Loreto Gesualdo, Alberto Mazza, Cristina Giannattasio, Alessandro Maloberti, Massimo Volpe, Giuliano Tocci, Guido Iaccarino, Pietro Nazzaro, Ferruccio Galletti, Claudio Ferri, Giovambattista Desideri, Francesca Viazzi, Roberto Pontremoli, Maria Lorenza Muiesan, Guido Grassi, Claudio Borghi
Summary: This study investigates the association between very high HDL-cholesterol levels and cardiovascular mortality (CVM), and whether this association is influenced by hyperuricemia. The results show a J-shaped association between high HDL-cholesterol levels and CVM in women, but not in men. Additionally, the risk of CVM related to high HDL-cholesterol is increased in women with hyperuricemia.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Chemistry, Analytical
Luca Neri, Matt T. Oberdier, Antonio Augello, Masahito Suzuki, Ethan Tumarkin, Sujai Jaipalli, Gian Angelo Geminiani, Henry R. Halperin, Claudio Borghi
Summary: Recent advancements in smart, wearable technologies have led to the ability to detect various medical conditions, including pathologic cardiac rhythms, through continuous collection and real-time analysis of electrocardiogram (ECG) data. This study presents a modified QRS detection algorithm, AMPT, which is a simplified version of the well-established Pan-Tompkins algorithm. Using archived ECG data, the AMPT algorithm demonstrated improved computational efficiency by 5-20x compared to the Pan-Tompkins algorithm, while also universally enhancing correctness. These findings support the translation of the AMPT algorithm to mobile platforms for continuous, real-time QRS detection.
Article
Nutrition & Dietetics
Arrigo F. G. Cicero, Federica Fogacci, Sergio D'Addato, Elisa Grandi, Elisabetta Rizzoli, Claudio Borghi
Summary: Although coffee has been linked to various cardiovascular benefits, its impact on blood pressure remains unclear. This study found that moderate coffee consumption was associated with lower systolic blood pressure, while heavy coffee consumption was associated with higher levels of systolic blood pressure.
Review
Medicine, General & Internal
Cormac Kennedy, Peter Hayes, Sulafa Salama, Martina Hennessy, Federica Fogacci
Summary: This study found that the GLP-1 RA drug semaglutide can significantly reduce weight and improve blood pressure in non-diabetic patients. The analysis included 6 RCT trials with a total of 4744 participants, and the results showed that the participants had normal blood pressure at baseline. After semaglutide treatment, the mean reduction in systolic blood pressure was 4.83 mmHg, and the mean reduction in diastolic blood pressure was 2.45 mmHg.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Serkan Bolat, Gozde Erturk Zararsiz, Kuebra Dogan, Necla Kochan, Serra I. Yerlitas, Ahu Cephe, Gokmen Zararsiz, Arrigo F. G. Cicero
Summary: This study aimed to evaluate the concordance of LDL-C-estimating equations with direct enzymatic measurement in diabetic and prediabetic populations. It was found that all equations had lower concordance with direct enzymatic measurement in diabetic and prediabetic groups, with the Martin-Hopkins extended equation performing the best. Additionally, direct assay methods can be used at low values of the non-HDL-C/TG ratio (<2.4) as the performance of the equations in LDL-C estimation decreases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Juan Tamargo, Stefan Agewall, Claudio Borghi, Claudio Ceconi, Elisabetta Cerbai, Gheorghe A. Dan, Peter Ferdinandy, Erik Lerkevang Grove, Bianca Rocca, Patrick Sulzgruber, Anne Grete Semb, Samuel Sossalla, Alexander Niessner, Juan Carlos Kaski, Dobromir Dobrev
Summary: Cardiovascular diseases (CVD) are the leading cause of death globally, and current pharmacotherapy is not optimal. Therefore, there is an urgent need to develop new drugs with higher efficacy and better safety profiles. This review summarizes the recent advances in cardiovascular pharmacology in 2022, including the approval of first-in-class drugs for the treatment of obstructive hypertrophic cardiomyopathy, type 2 diabetes mellitus, and heart failure independent of left ventricular ejection fraction. It also discusses the repurposing of existing drugs and the potential of new therapies for the treatment of various cardiovascular diseases.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2023)
Review
Biochemistry & Molecular Biology
Federica Piani, Giovanni Tossetta, Gabriel Cara-Fuentes, Davide Agnoletti, Daniela Marzioni, Claudio Borghi
Summary: This systematic review examines the role of Cluster of Differentiation (CD) 93 in cardiovascular disease. A total of 182 studies were analyzed, indicating a potential association between CD93 and cardiovascular risk factors and diseases (such as hypertension, dyslipidemia, heart failure, coronary artery disease, and ischemic stroke). However, the quality and scope of the studies are insufficient to determine the diagnostic and prognostic value of CD93 in cardiovascular disease.
Article
Biochemistry & Molecular Biology
Alessia Silla, Federica Fogacci, Angela Punzo, Silvana Hrelia, Patrizia Simoni, Cristiana Caliceti, Arrigo F. G. Cicero
Summary: Atherosclerosis and ASCVD can be improved by reducing the levels of LDL cholesterol. A new injectable antibody targeting PCSK9, called Evolocumab, has been approved for better lipid control in high-risk individuals. The use of Evolocumab has shown significant improvement in blood pressure and arterial pulse wave velocity, as well as a decrease in H2O2 production.
Article
Nutrition & Dietetics
Arrigo F. G. Cicero, Federica Fogacci, Marina Giovannini, Elisabetta Rizzoli, Elisa Grandi, Sergio D'Addato, Claudio Borghi
Summary: The DESCO study found that dietary supplementation with plant sterols significantly improved the lipid profile, particularly the levels of total cholesterol, low-density lipoprotein cholesterol, and apolipoprotein B-100. Compared to placebo, the intake of plant sterols also resulted in greater reductions in lipid levels, with better efficacy observed in individuals following a Mediterranean dietary pattern.
Article
Medicine, General & Internal
Mahsa Mohajeri, Reza Mohajery, Arrigo F. G. Cicero
Summary: This study investigated the association between adherence to the Mediterranean diet and serum inflammatory factors, total antioxidant capacity, appetite, and symptoms of COVID-19 patients. The results showed that patients who adhered more to the Mediterranean diet had milder symptoms and lower levels of serum inflammatory factors. Therefore, clinical trials are suggested to confirm the effectiveness of the Mediterranean diet.
MEDICINA-LITHUANIA
(2023)
Review
Endocrinology & Metabolism
Federica Fogacci, Claudio Borghi, Sergio Davinelli, Giovanni Scapagnini, Arrigo F. G. Cicero
Summary: The purpose of this study was to evaluate the effect of different anti-oestrogen therapy on plasma Lp(a) level in postmenopausal women. The results showed that anti-oestrogen therapy significantly reduced Lp(a) levels in women.
Review
Peripheral Vascular Disease
Alessandro Maloberti, Alessandro Mengozzi, Elisa Russo, Arrigo Francesco Giuseppe Cicero, Fabio Angeli, Enrico Agabiti Rosei, Carlo Maria Barbagallo, Bruno Bernardino, Michele Bombelli, Federica Cappelli, Edoardo Casiglia, Rosario Cianci, Michele Ciccarelli, Massimo Cirillo, Pietro Cirillo, Giovambattista Desideri, Lanfranco D'Elia, Raffaella Dell'Oro, Rita Facchetti, Claudio Ferri, Ferruccio Galletti, Cristina Giannattasio, Loreto Gesualdo, Guido Iaccarino, Luciano Lippa, Francesca Mallamaci, Stefano Masi, Maria Masulli, Alberto Mazza, Maria Lorenza Muiesan, Pietro Nazzaro, Gianfranco Parati, Paolo Palatini, Paolo Pauletto, Roberto Pontremoli, Nicola Riccardo Pugliese, Fosca Quarti-Trevano, Marcello Rattazzi, Gianpaolo Reboldi, Giulia Rivasi, Massimo Salvetti, Valerie Tikhonoff, Giuliano Tocci, Andrea Ungar, Paolo Verdecchia, Francesca Viazzi, Massimo Volpe, Agostino Virdis, Guido Grassi, Claudio Borghi, Italian Soc Hypertension SIIA
Summary: The relationship between serum uric acid and cardiovascular diseases, kidney function, and metabolic syndrome has been studied extensively. However, there are still unanswered questions, such as determining the optimal cutoff for cardiovascular risk, the need for adjustments of uric acid values for kidney function, and the precise role of uric acid in metabolic syndrome.
HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION
(2023)
Review
Biochemistry & Molecular Biology
Federica Fogacci, Valentina Di Micoli, Ashot Avagimyan, Marina Giovannini, Egidio Imbalzano, Arrigo F. G. Cicero
Summary: This review aims to discuss the best strategy for utilizing molecular biology techniques to examine the genetic role of Lp(a) and its significance in clinical research and practice. The diversity in size of apo(a) is primarily caused by copy number variations in the KIV2 domains.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)