Editorial Material
Medicine, General & Internal
Maximilian F. Konig, Vasanth Sathiyakumar, Casey M. Phan, Steven P. Schulman, Allan C. Gelber
Summary: A 38-year-old female mail carrier experienced sudden chest pain and shortness of breath on her way home from work, with examination revealing abnormalities in her heart.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Editorial Material
Engineering, Biomedical
Ke Huang, Ke Cheng
Summary: Inflamed heart tissue can be repaired after a heart attack by using a degradable matrix that can be infused intravascularly and binds to leaky blood vessels.
NATURE BIOMEDICAL ENGINEERING
(2023)
Editorial Material
Medicine, General & Internal
MaryAnn Dakkak
Summary: In this narrative medicine essay, a family medicine physician shares her personal story as someone who is obese and disabled. She talks about her own process of addressing stigma and bias around obesity and how she is now helping patients work toward improved physical function and overall health goals.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Chemistry, Physical
Seth C. Martin, Hendrik Hansen-Goos, Roland Roth, Brian B. Laird
Summary: By using simulations and theoretical calculations, we investigated the influence of wall curvature on the interfacial thermodynamics of solid-fluid interfaces. Our results show that the surface thermodynamics of the system is consistent with the predictions of morphometric thermodynamics for both positive and negative wall curvatures.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Psychology, Multidisciplinary
Sabrina N. Grondhuis, Angela Jimmy, Carolina Teague, Nicolas M. Brunet
Summary: Previous studies have found that it is more difficult to identify emotional expressions displayed by older faces compared to younger faces. Through experiments, it was discovered that this difficulty may be due to age-related decline in facial muscle ability and age-related physical changes in the face.
FRONTIERS IN PSYCHOLOGY
(2021)
Editorial Material
Hematology
Geoffrey L. Uy
Summary: The study demonstrates a novel T-cell-bispecific antibody (TCB) targeting intracellular WT1 in AML, resulting in T-cell activation and killing of leukemia cells with minimal effect on normal hematopoietic cells.
Review
Chemistry, Inorganic & Nuclear
Tomoki Tateishi, Masahiko Yoshimura, Shun Tokuda, Fuyuki Matsuda, Daishi Fujita, Shuhei Furukawa
Summary: Cage-like molecules formed by the coordination of metal ions and organic links have unique chemical properties and design flexibility, and are pushing the boundaries of science. This review article compares coordination cages (CCs) and metal-organic cages (MOCs) from two distinct chemistry communities, highlighting their similarities and differences. The article provides insights into synthetic conditions and identifies new research directions in the field.
COORDINATION CHEMISTRY REVIEWS
(2022)
Review
Immunology
Martin Kolev, Madhumita Das, Monica Gerber, Scott Baver, Pascal Deschatelets, Maciej M. Markiewski
Summary: Recent studies have shown that complement plays a role in accelerating cancer progression by suppressing antitumor immunity in the tumor microenvironment. Activation of intracellular complement is crucial for the survival of immune cells, making it important for tumor cell survival and growth. Additionally, intracellular complement activation is essential for priming antitumor T cell responses.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Cell Biology
Samuel Ovadia, Alaz Ozcan, Andres Hidalgo
Summary: The biology and functions of neutrophils exhibit notable circadian patterns influenced by the circadian clock. The immune and inflammatory systems, among numerous physiological targets, are specifically influenced by these circadian oscillations. This review discusses the regulation of neutrophils, the wildcard of the immune system, by circadian mechanisms. It explores both intrinsic and extrinsic diurnal mechanisms governing the overall physiology and function of neutrophils, and speculates on unexplored relationships such as topology, metabolism, and tissue clock regulation, aiming to identify novel avenues for research in the field of circadian immunity.
JOURNAL OF LEUKOCYTE BIOLOGY
(2023)
Article
Plant Sciences
Leander Ehmke, Gerd Hause, Ralf Bernd Kloesgen, Bationa Bennewitz
Summary: The inner membrane of mitochondria serves as a major barrier between cytosol and mitochondrial matrix, facilitating the controlled exchange of metabolites, ions, and proteins. Inside-out inner membrane vesicles are a useful tool for studying the export of substances from the matrix to the intermembrane space. This article presents a protocol for isolating inside-out vesicles of the inner membrane of plant mitochondria and demonstrates their physiological activity.
FRONTIERS IN PLANT SCIENCE
(2023)
Review
Cell Biology
Sarah R. Chadwick, Sergio Grinstein, Spencer A. Freeman
Summary: The role of specific proteins and lipids in endocytic traffic has been extensively studied, but little is known about the contribution of endocytic fluid to these events. Experimental findings suggest an intimate association between luminal ions, their transport, and endocytic traffic, but mechanisms for how cells sense inorganic ions and transmit this information remain largely unknown.
CURRENT OPINION IN CELL BIOLOGY
(2021)
Article
Geochemistry & Geophysics
Jiejie Lyu, Fuchun Li, Chonghong Zhang, Laurie Gower, Scott Wasman, Jun Sun, Guoguo Yang, Jiani Chen, Lixin Gu, Xu Tang, Gary Scheiffele
Summary: Microscale analytical methods were used to investigate calcified bacteria and CaCO3 crystallites induced by the ureolytic strain Bacillus cereus LV-1. The research found that bacterial-shaped pores were distributed on the surface and/or inside the crystallites, with different mineral phases present from the inside to the outside of the mineral shell. This study suggests that calcified bacteria can serve as a structural unit in microbial induced carbonate precipitates.
Article
Neurosciences
Amanda C. Marshall, Antje Gentsch-Ebrahimzadeh, Simone Schutz-Bosbach
Summary: Neuroscientific studies have shown that the brain can predictively refine neural resources to process cardiac feedback and use these cues to enable more efficient processing of external sensory information. The alignment of external to internal signals enhances interoceptive processing and facilitates suppression of visual stimuli and repetition suppression of auditory feedback. This research provides evidence for the importance of aligning internal and external signals for efficient sensory processing.
Article
Nutrition & Dietetics
Iryna Rybak, Alexis E. Carrington, Simran Dhaliwal, Aliza Hasan, Hera Wu, Waqas Burney, Jessica Maloh, Raja K. Sivamani
Summary: The study demonstrates that daily consumption of almonds can improve several aspects of photoaging such as facial wrinkles and pigment intensity in postmenopausal women.
Review
Hematology
Andrew P. Stone, Thais F. Nascimento, Maria N. Barrachina
Summary: Megakaryocytes (MKs), the largest hematopoietic cells, can be generated from multiple pathways. Recent studies have shown that changes in the bone marrow microenvironment can affect MK development. MKs can also actively shape the bone marrow niche.