2,2-difluorovinyl benzoates for diverse synthesis of gem-difluoroenol ethers by Ni-catalyzed cross-coupling reactions

Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H• Transfer from a Nickel Hydride

(2020) Chengbo Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of gem-Difluoroalkenes by Merging Ni-Catalyzed C–F and C–C Bond Activation in Cross-Electrophile Coupling

(2019) Decai Ding et al.   ORGANIC LETTERS

Efficient Synthesis of α-Trifluoromethyl Carboxylic Acids and Esters via Fluorocarboxylation of gem-Difluoroalkenes

(2019) Woo-Jin Yoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The ortho Difluoroalkylation of Aryliodanes with Enol Silyl Ethers: Rearrangement Enabled by a Fluorine Effect

(2019) Xin Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Selective Carbonylation of gem -Difluoroalkenes: A Practical Synthesis of Difluoromethylated Esters

(2019) Jiawang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem -Difluoroalkenes

(2019) Haidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Decarboxylation of Aryl Carbamates for Converting Phenols into Aromatic Amines

(2019) Akihiro Nishizawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bis(dialkylphosphino)ferrocene-Ligated Nickel(II) Precatalysts for Suzuki–Miyaura Reactions of Aryl Carbonates

(2019) Emily L. Barth et al.   ORGANOMETALLICS

Decarbonylative Cross-Couplings: Nickel Catalyzed Functional Group Interconversion Strategies for the Construction of Complex Organic Molecules

(2018) Lin Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition Metal-Mediated and -Catalyzed C-F Bond Activation via Fluorine Elimination

(2018) Takeshi Fujita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Picking one out of three: selective single C-F activation in trifluoromethyl groups

(2018) Florian Jaroschik   CHEMISTRY-A EUROPEAN JOURNAL

Intermediacy of Ni–Ni Species in sp2 C–O Bond Cleavage of Aryl Esters: Relevance in Catalytic C–Si Bond Formation

(2018) Rosie J. Somerville et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Enantioselective Defluorinative α-Arylation of Secondary Amides

(2018) Young Jin Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Base-free nickel-catalysed decarbonylative Suzuki–Miyaura coupling of acid fluorides

(2018) Christian A. Malapit et al.   NATURE

Synthesis of gem-Difluoroalkenes via Nickel-Catalyzed Reductive C–F and C–O Bond Cleavage

(2018) Zhiyang Lin et al.   ACS Catalysis

Copper-Catalyzed Regioselective Monodefluoroborylation of Polyfluoroalkenes en Route to Diverse Fluoroalkenes

(2017) Hironobu Sakaguchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling of gem-Difluoroalkenes with Unactivated Secondary and Tertiary Alkyl Halides

(2017) Xi Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in the synthesis and CF functionalization of gem-difluoroalkenes

(2017) Xuxue Zhang et al.   TETRAHEDRON LETTERS

Synthesis of Functionalized gem-Difluoroalkenes via a Photocatalytic Decarboxylative/Defluorinative Reaction

(2016) Tiebo Xiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Asymmetric Arylation/Defluorination of 1-(Trifluoromethyl)alkenes Forming Enantioenriched 1,1-Difluoroalkenes

(2016) Yinhua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lubiprostone: a novel treatment for chronic constipation

(2016) Brian Lacy   Clinical Interventions in Aging

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Carbonyl reduction pathways in drug metabolism

(2013) Petra Malátková et al.   DRUG METABOLISM REVIEWS

Isolation, Structure, and Reactivity of an Arylnickel(II) Pivalate Complex in Catalytic C–H/C–O Biaryl Coupling

(2013) Kei Muto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed gem-Difluoroolefination of Diazo Compounds with TMSCF3 via C–F Bond Cleavage

(2013) Mingyou Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

γ-Selective Addition to 1,1-Difluoroallenes: Three-component Coupling Leading to 2,2-Disubstituted 1,1-Difluoroalkenes

(2012) Kohei Fuchibe et al.   CHEMISTRY LETTERS

Synthesis and Metal-Catalyzed Reactions of gem-Dihalovinyl Systems

(2011) Giorgio Chelucci   CHEMICAL REVIEWS

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Nickel-catalyzed amination of aryl carbamates and sequential site-selective cross-couplings

(2011) Tehetena Mesganaw et al.   Chemical Science

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

Construction of Polysubstituted Olefins through Ni-Catalyzed Direct Activation of Alkenyl CO of Substituted Alkenyl Acetates

(2010) Chang-Liang Sun et al.   CHEMISTRY-A EUROPEAN JOURNAL

Efficient Synthesis of 2,2-Diaryl-1,1-difluoroethenes via Consecutive Cross-Coupling Reactions of 2,2-Difluoro-1-tributylstannylethenylp-Toluenesulfonate

(2010) Seung Yeon Han et al.   ORGANIC LETTERS

Preparation of a Stable Trifluoroborate Salt for the Synthesis of 1-Aryl-2,2-difluoro-enolethers and/or 2,2-Difluoro-1-aryl-ketones via Palladium-Mediated Cross-Coupling

(2009) Jason D. Katz et al.   JOURNAL OF ORGANIC CHEMISTRY

Suzuki−Miyaura Coupling of Aryl Carbamates, Carbonates, and Sulfamates

(2009) Kyle W. Quasdorf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis ofgem-Difluoroalkenes via β-Fluoride Elimination of Organorhodium(I)

(2008) Tomoya Miura et al.   CHEMISTRY LETTERS

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS

Biaryl Construction via Ni-Catalyzed C−O Activation of Phenolic Carboxylates

(2008) Bing-Tao Guan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY