DL-3n-Butylphthalide Improves Blood–Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion

Caveolin-1 Regulates Perivascular Aquaporin-4 Expression After Cerebral Ischemia

(2020) Irina Filchenko et al.   Frontiers in Cell and Developmental Biology

Targeting Water in Brain: Role of Aquaporin-4 in Ischemic Brain Edema

(2019) Muyassar Mamtilahun et al.   CURRENT DRUG TARGETS

Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats

(2019) Pan-Ting Zhou et al.   CNS Neuroscience & Therapeutics

DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins

(2019) Zhan-Ying Ye et al.   CHINESE MEDICAL JOURNAL

Dl-3-n-Butylphthalide (NBP)：A Promising Therapeutic Agent for Ischemic Stroke

(2018) S Wang et al.   CNS & Neurological Disorders-Drug Targets

Dl-3-N-butylphthalide attenuates ischemic reperfusion injury by improving the function of cerebral artery and circulation

(2018) Chuan Qin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction

(2017) Chenhao Zhang et al.   MEDICINE

The Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway as a Discovery Target in Stroke

(2016) Jing Sun et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke

(2016) Renée J. Turner et al.   Frontiers in Cellular Neuroscience

Translational Stroke Research on Blood-Brain Barrier Damage: Challenges, Perspectives, and Goals

(2016) Yejie Shi et al.   Translational Stroke Research

A Review of Recent Advances in Neuroprotective Potential of 3-N-Butylphthalide and Its Derivatives

(2016) Idriss Ali Abdoulaye et al.   Biomed Research International

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Hypoxia-controlled matrix metalloproteinase-9 hyperexpression promotes behavioral recovery after ischemia

(2015) Hongxia Cai et al.   Neuroscience Bulletin

Mesenchymal Stem Cells Maintain Blood-Brain Barrier Integrity by Inhibiting Aquaporin-4 Upregulation After Cerebral Ischemia

(2014) Guanghui Tang et al.   STEM CELLS

Silica-coated superparamagnetic iron oxide nanoparticles targeting of EPCs in ischemic brain injury

(2013) Qianyun Li et al.   BIOMATERIALS

Ouabain induces endocytosis and degradation of tight junction proteins through ERK1/2-dependent pathways

(2013) Ruth Rincon-Heredia et al.   EXPERIMENTAL CELL RESEARCH

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Effect of Propofol Post-treatment on Blood–Brain Barrier Integrity and Cerebral Edema After Transient Cerebral Ischemia in Rats

(2013) Jae Hoon Lee et al.   NEUROCHEMICAL RESEARCH

Surgery-Related Thrombosis Critically Affects the Brain Infarct Volume in Mice Following Transient Middle Cerebral Artery Occlusion

(2013) Xiaojie Lin et al.   PLoS One

Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Acute Ischemic Stroke

(2013) Shaheen E. Lakhan et al.   Frontiers in Neurology

DL-3-n-Butylphthalide, an Anti-Oxidant Agent, Prevents Neurological Deficits and Cerebral Injury Following Stroke per Functional Analysis, Magnetic Resonance Imaging and Histological Assessment

(2012) Lihong Zhang et al.   CURRENT NEUROVASCULAR RESEARCH

Potential Contribution of Hypoxia-Inducible Factor-1α, Aquaporin-4, and Matrix Metalloproteinase-9 to Blood–Brain Barrier Disruption and Brain Edema After Experimental Subarachnoid Hemorrhage

(2012) Zhong Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Effects of DL-3-n-Butylphthalide on Vascular Dementia and Angiogenesis

(2012) Lihong Zhang et al.   NEUROCHEMICAL RESEARCH

Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke

(2012) R. Khatri et al.   NEUROLOGY

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

(2012) C. Coletta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design, synthesis and evaluation of nitric oxide releasing derivatives of 3-n-butylphthalide as antiplatelet and antithrombotic agents

(2011) Xuliang Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

dl-3-n-Butylphthalide prevents neuronal cell death after focal cerebral ischemia in mice via the JNK pathway

(2010) Jimei Li et al.   BRAIN RESEARCH

3-n-butylphthalide (NBP) reduces apoptosis and enhances vascular endothelial growth factor (VEGF) up-regulation in diabetic rats

(2010) Ting Zhang et al.   NEUROLOGICAL RESEARCH

Enhanced angiogenesis with dl-3n-butylphthalide treatment after focal cerebral ischemia in RHRSP

(2009) Song-Jie Liao et al.   BRAIN RESEARCH

Random process estimator for laser speckle imaging of cerebral blood flow

(2009) Peng Miao et al.   OPTICS EXPRESS

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

The Role of Aquaporin-4 Polymorphisms in the Development of Brain Edema After Middle Cerebral Artery Occlusion

(2008) Ilka Kleffner et al.   STROKE

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE