Understanding the Development, Standardization, and Validation Process of Alternative In Vitro Test Methods for Regulatory Approval from a Researcher Perspective

Alternative Methods for Testing Botulinum Toxin: Current Status and Future Perspectives

(2020) Mahesh Raj Nepal et al.   Biomolecules & Therapeutics

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes

(2020) Hana Barosova et al.   ACS Nano

Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale

(2020) Sabina Halappanavar et al.   Particle and Fibre Toxicology

New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing

(2020) Jose Zavala et al.   International Journal of Environmental Research and Public Health

Developing OECD test guidelines for regulatory testing of nanomaterials to ensure mutual acceptance of test data

(2019) Kirsten Rasmussen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms

(2018) Chris S. Pridgeon et al.   ARCHIVES OF TOXICOLOGY

Alternative test models for skin ageing research

(2018) Motoki Nakamura et al.   EXPERIMENTAL DERMATOLOGY

Cell cultures in drug discovery and development: The need of reliable in vitro-in vivo extrapolation for pharmacodynamics and pharmacokinetics assessment

(2018) Karol Jaroch et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

(2018) Anna Bal-Price   ALTEX-Alternatives to Animal Experimentation

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

(2018) David Pamies   ALTEX-Alternatives to Animal Experimentation

Minimum information reporting in bio–nano experimental literature

(2018) Matthew Faria et al.   Nature Nanotechnology

Protecting Animals and Enabling Research in the European Union: An Overview of Development and Implementation of Directive 2010/63/EU

(2017) I Anna S Olsson et al.   ILAR JOURNAL

Steps towards the international regulatory acceptance of non-animal methodology in safety assessment

(2017) Fiona Sewell et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Alternative Animal and Non-Animal Models for Drug Discovery and Development: Bonus or Burden?

(2016) Irlan Almeida Freires et al.   PHARMACEUTICAL RESEARCH

The botulinum neurotoxin LD50 test - problems and solutions

(2016) Silke Bitz   ALTEX-Alternatives to Animal Experimentation

Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology

(2015) Sarah Gordon   ALTEX-Alternatives to Animal Experimentation

Integrated testing strategies (ITS) for safety assessment

(2015) Costanza Rovida   ALTEX-Alternatives to Animal Experimentation

Systems toxicology

(2014) Thomas HArtung   ALTEX-Alternatives to Animal Experimentation

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

(2014) Natalie Alépée   ALTEX-Alternatives to Animal Experimentation

Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

(2013) Marcel Leist et al.   ARCHIVES OF TOXICOLOGY

Ethical and Scientific Considerations Regarding Animal Testing and Research

(2011) Hope R. Ferdowsian et al.   PLoS One

In Silico Toxicology – Non-Testing Methods

(2011) Hannu Raunio   Frontiers in Pharmacology

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

(2008) W. Lilienblum et al.   ARCHIVES OF TOXICOLOGY