Article
Environmental Sciences
Arash Derakhshan, Huan Shu, Maarten A. C. Broeren, Christian H. Lindh, Robin P. Peeters, Andreas Kortenkamp, Barbara Demeneix, Carl-Gustaf Bornehag, Tim I. M. Korevaar
Summary: The study found that elevated levels of certain phthalate metabolites in maternal urine during pregnancy may be associated with abnormalities in thyroid system markers. These results are in line with findings from experimental studies.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Pharmacology & Pharmacy
Sapna Sedha, Hoomin Lee, Siddhartha Singh, Sunil Kumar, Subodh Jain, Ajaz Ahmad, Yousef A. Bin Jardan, Sonam Sonwal, Shruti Shukla, Jesus Simal-Gandara, Jianbo Xiao, Yun Suk Huh, Young-Kyu Han, Vivek K. Bajpai
Summary: Phthalates, pervasive compounds widely used in various products, have been linked to developmental and reproductive toxicity, highlighting the importance of developing non-toxic alternatives to reduce risks of exposure. More epidemiological studies are needed to further understand the impact of phthalates on human health.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Duygu Aydemir, Mufide Aydogan-Ahbab, Nurhayat Barlas, Nuriye Nuray Ulusu
Summary: Phthalates are widely used as plasticizers and can be found in various products. They have been associated with endocrine disruption and peroxisome proliferator effects, leading to diseases such as diabetes, obesity, infertility, cardiovascular diseases, metabolic syndrome, and cancer. In this study, the authors evaluated the effects of in-utero exposure to DHP and DCHP on liver metabolism in male and female rats. They found that exposure to these phthalates caused liver damage and impaired oxidative stress metabolism. This study highlights the importance of regulating and restricting phthalates in industrial products.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Environmental Sciences
Kumar Vishven Naveen, Kandasamy Saravanakumar, Xin Zhang, Anbazhagan Sathiyaseelan, Myeong-Hyeon Wang
Summary: Phthalates, widely used as plasticizers, may pose health risks to mammals. Fungi, with their effective enzyme secretory system, offer potential advantages for phthalate bioremediation by breaking down ester compounds and reducing phthalate pollution in the environment.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Victoria S. Jiang, Antonia M. Calafat, Paige L. Williams, Jorge E. Chavarro, Jennifer B. Ford, Irene Souter, Russ Hauser, Lidia Minguez-Alarcon
Summary: This study examined the temporal trends in urinary concentrations of various endocrine disrupting chemicals (EDCs) and their replacements. It found that the concentrations of traditional EDCs such as phenols and phthalates have decreased over time, while the concentrations of replacement chemicals such as DINCH metabolites and triclocarban have increased.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Hao-Wen Zhong, Jia-Liang Guo, Yi-Bin Hu, Lu-Lu Jia, Ying Guo
Summary: A study on 288 college students who love eating takeaway food reveals that the frequency of takeaway consumption is associated with phthalate exposure levels, but not significantly correlated with DNA oxidative damage levels.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Jung-Wei Chang, Hsin-Chang Chen, Heng-Zhao Hu, Wan-Ting Chang, Po-Chin Huang, I-Jen Wang
Summary: The study shows that low-dose phthalate exposure enhances the immune system response in children with asthma. Monobenzyl phthalate is identified as the main contributing factor.
Article
Environmental Sciences
Min Zhang, Yan-Ling Deng, Chong Liu, Pan-Pan Chen, Qiong Luo, Yu Miao, Fei-Peng Cui, Long-Qiang Wang, Ming Jiang, Qiang Zeng
Summary: This study examined the associations between phthalate exposures and thyroid function, as well as the potential mediating role of oxidative stress, among patients with thyroid nodules. The results showed that certain phthalate metabolites were linked to altered thyroid function and increased oxidative stress biomarkers. Additionally, lipid peroxidation may serve as an intermediate mechanism in the effects of phthalate exposures on thyroid function among patients with benign thyroid nodules.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Delnia Ahmadpour, Sakina Mhaouty-Kodja, Valerie Grange-Messent
Summary: Exposure to low doses of DEHP or an environmental phthalate mixture was found to increase BBB permeability, affect glial activation and neuroinflammation in specific brain regions. This suggests that exposure to endocrine disruptors like phthalates may pose a risk to cerebrovascular function.
Article
Environmental Sciences
Susana Santos, Chalana M. Sol, Charissa Van Zwol-Janssens, Elise M. Philips, Alexandros G. Asimakopoulos, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan, Vincent W. V. Jaddoe, Leonardo Trasande
Summary: Exposure to phthalates during pregnancy may lead to fetal growth restriction and preterm birth. Different trimester-specific exposures to phthalates may have varying effects on fetal growth and birth outcomes.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Engineering, Environmental
Hongdan Wang, Yunqing Wang, Qiaoning Wang, Min Lv, Xizhen Zhao, Yunxia Ji, Xiaoyue Han, Xiaoyan Wang, Lingxin Chen
Summary: Microplastics have toxic effects on aquatic organisms due to their characteristics of large specific surface area, high hydrophobicity, and surface charge. This study investigated the effects of polyvinyl chloride-microplastics (PVC-MPs) and di(2-ethylhexyl) phthalate (DEHP) on zebrafish embryos and larvae. It was found that PVC-MPs reduced the hatching rate of zebrafish embryos and caused zebrafish mortality, while DEHP slowed down the death rate. The compound pollution of PVC-MPs and DEHP induced reactive oxygen species production and activated antioxidant defense signaling pathway. Moreover, PVC-MPs inhibited the expression of genes related to cardiac development, while the combined pollution showed an antagonistic effect.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
A. Yu. Andreyeva, V. V. Lobko, O. L. Gostyukhina, A. A. Tkachuk, A. I. Murashova, L. V. Malakhova, E. S. Kladchenko
Summary: Mussels exposed to di-(2-ethylhexyl) phthalate (DEHP) for 24 h and 48 h showed decreased spontaneous reactive oxygen production (ROS) levels in hemocytes and a decrease in agranulocyte number in hemolymph. DEHP accumulated in the hepatopancreas of mussels, leading to increased catalase (CAT) activity after 24 h. CAT activity recovered to control levels after 48 h, while superoxide dismutase (SOD) activity increased at this time point. These results suggest that DEHP can affect immune properties of hemocytes and induce a non-specific antioxidant stress response.
MARINE POLLUTION BULLETIN
(2023)
Article
Environmental Sciences
Giuseppa Di Bella, Miriam Porretti, Mirea Cafarelli, Federica Litrenta, Angela Giorgia Potorti, Vincenzo Lo Turco, Ambrogina Albergamo, Monica Xhilari, Caterina Faggio
Summary: Plastic accumulation and degradation into microplastics is an environmental issue due to their widespread presence and release of intrinsic chemicals that can act as endocrine disruptors. Monitoring plastic additives in biological matrices, such as blood, can help understand the relationship between human exposure and health outcomes. This study analyzed the levels and frequencies of specific plasticizers in Sicilian women's blood of different ages, finding higher concentrations in younger females, possibly due to increased use of plastic products in daily life.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Review
Food Science & Technology
Patrick Harmon, Rainer Otter
Summary: This review summarizes the available toxicity, migration, and human biomonitoring data of several non-ortho phthalate plasticizers used in food packaging and processing. The study demonstrates that these plasticizers have been well-studied and are generally of low toxicity, with minimal adverse effects on human health.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Environmental Sciences
Fiorella Lucarini, Marc Blanchard, Tropoja Krasniqi, Nicolas Duda, Gaelle Bailat Rosset, Alessandro Ceschi, Nicolas Roth, Nancy B. Hopf, Marie-Christine Broillet, Davide Staedler
Summary: A study on exposure of Swiss children to phthalates using disposable diaper urine sampling technique revealed limited exposure and detection of potentially new emerging phthalates. The optimized protocol for urine collection from disposable diapers provided a promising approach for further phthalate biomonitoring studies on young children. This study presents an initial snapshot of the Swiss children's exposure to phthalates, contributing valuable insights for future research in this area.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)