Elongational stalling activates mitoribosome-associated quality control

Rescuing stalled mammalian mitoribosomes – what can we learn from bacteria?

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How a circularized tmRNA moves through the ribosome

(2019) Christopher D. Rae et al.   SCIENCE

Mechanism for recycling tRNAs on stalled ribosomes

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Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

(2019) Ting Su et al.   NATURE

C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis

(2019) Shreekara Gopalakrishna et al.   NUCLEIC ACIDS RESEARCH

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

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Mechanism of ribosome stalling during translation of a poly(A) tail

(2019) Viswanathan Chandrasekaran et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Current Developments in Coot for Macromolecular Model Building of Electron Cryo‐microscopy and Crystallographic Data

(2019) Ana Casañal et al.   PROTEIN SCIENCE

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Real-space refinement in PHENIX for cryo-EM and crystallography

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Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes

(2018) David J. F. Ramrath et al.   SCIENCE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation

(2017) André Heuer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ABCE1: A special factor that orchestrates translation at the crossroad between recycling and initiation

(2017) Eder Mancera-Martínez et al.   RNA Biology

The structure of the yeast mitochondrial ribosome

(2017) Nirupa Desai et al.   SCIENCE

Structure of the Human Mitochondrial Ribosome Studied In Situ by Cryoelectron Tomography

(2017) Robert Englmeier et al.   STRUCTURE

Recurring RNA structural motifs underlie the mechanics of L1 stalk movement

(2017) Srividya Mohan et al.   Nature Communications

Structures of the human mitochondrial ribosome in native states of assembly

(2017) Alan Brown et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation

(2017) André Heuer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maturation of selected human mitochondrial tRNAs requires deadenylation

(2017) Sarah F Pearce et al.   eLife

The process of mammalian mitochondrial protein synthesis

(2016) Nicole Mai et al.   CELL AND TISSUE RESEARCH

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosome-associated protein quality control

(2016) Onn Brandman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation

(2016) Ryuta Ishimura et al.   eLife

Homozygous p.V116* mutation inC12orf65results in Leigh syndrome

(2015) Eri Imagawa et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

Delineation of C12orf65-related phenotypes: a genotype–phenotype relationship

(2014) Ronen Spiegel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mutations in the mitochondrial gene C12ORF65 lead to syndromic autosomal recessive intellectual disability and show genotype phenotype correlation

(2013) Rebecca Buchert et al.   European Journal of Medical Genetics

Optic Atrophy and a Leigh-Like Syndrome Due to Mutations in the C12orf65 Gene

(2013) Gena Heidary et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Novel C12orf65 mutations in patients with axonal neuropathy and optic atrophy

(2013) A. Tucci et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Low-resolution refinement tools inREFMAC5

(2012) Robert A. Nicholls et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A homozygous mutation ofC12orf65causes spastic paraplegia with optic atrophy and neuropathy (SPG55)

(2012) Haruo Shimazaki et al.   JOURNAL OF MEDICAL GENETICS

ViennaRNA Package 2.0

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Mutations in C12orf65 in Patients with Encephalomyopathy and a Mitochondrial Translation Defect

(2010) Hana Antonicka et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit Joining

(2010) Marco Gartmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism for Activation of GTP Hydrolysis on the Ribosome

(2010) R. M. Voorhees et al.   SCIENCE

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

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