Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling

(2018) Debanjan Dhar et al.   CANCER CELL

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

(2018) Nikos Koundouros et al.   Frontiers in Oncology

Senescence and aging: Causes, consequences, and therapeutic avenues

(2017) Domhnall McHugh et al.   JOURNAL OF CELL BIOLOGY

Oxidative Stress: Harms and Benefits for Human Health

(2017) Gabriele Pizzino et al.   Oxidative Medicine and Cellular Longevity

Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice

(2016) Michael I. Carr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

(2016) Michael I. Carr et al.   Cell Reports

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

(2015) Zhiwei Wang et al.   Oncotarget

Role of AKT signaling in DNA repair and clinical response to cancer therapy

(2014) Q. Liu et al.   NEURO-ONCOLOGY

Degradation of p53 by natural variants of the E6 protein of human papillomavirus type 16

(2013) JA WOON YI et al.   ONCOLOGY REPORTS

ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

(2012) Hugh S. Gannon et al.   CANCER CELL

Mdm2–p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin

(2011) Hugh S. Gannon et al.   DEVELOPMENTAL BIOLOGY

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

(2010) Hiroyuki Inuzuka et al.   CANCER CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Multi-stage chemical carcinogenesis in mouse skin: Fundamentals and applications

(2009) Erika L Abel et al.   Nature Protocols

Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells

(2009) Hui-Fang Li et al.   Radiation Oncology

The regulation of MDM2 by multisite phosphorylation—Opportunities for molecular-based intervention to target tumours?

(2009) David W. Meek et al.   SEMINARS IN CANCER BIOLOGY

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL