Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state

Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study

(2019) Pedro Azalim et al.   BIOCHEMICAL PHARMACOLOGY

Revisiting the binding kinetics and inhibitory potency of cardiac glycosides on Na+,K+-ATPase (α1β1): Methodological considerations

(2018) François Noël et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

A kinetic comparison between E2P and the E2P-like state induced by a beryllium fluoride complex in the Na,K-ATPase. Interactions with Rb+

(2018) Santiago Enrique Faraj et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Selective Assembly of Na,K-ATPase α2β2Heterodimers in the Heart

(2016) Michael Habeck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures and characterization of digoxin- and bufalin-bound Na+,K+-ATPase compared with the ouabain-bound complex

(2015) Mette Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of potassium ion uptake by the Na+/K+-ATPase

(2015) Juan P. Castillo et al.   Nature Communications

Na+,K+-ATPase Isoform Selectivity for Digitalis-Like Compounds Is Determined by Two Amino Acids in the First Extracellular Loop

(2014) Karl M. Weigand et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Digoxin Derivatives with Enhanced Selectivity for the α2 Isoform of Na,K-ATPase

(2014) Adriana Katz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site

(2013) M. Laursen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational Selection or Induced Fit? A Critical Appraisal of the Kinetic Mechanism

(2012) Austin D. Vogt et al.   BIOCHEMISTRY

Cooperativity in monomeric enzymes with single ligand-binding sites

(2011) Carol M. Porter et al.   BIOORGANIC CHEMISTRY

Metal Fluoride Complexes of Na,K-ATPase

(2011) Flemming Cornelius et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Selectivity of Digitalis Glycosides for Isoforms of Human Na,K-ATPase

(2010) Adriana Katz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase

(2010) Laure Yatime et al.   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structure of the sodium–potassium pump at 2.4 Å resolution

(2009) Takehiro Shinoda et al.   NATURE

Crystal structure of the sodium-potassium pump (Na+,K+-ATPase) with bound potassium and ouabain

(2009) H. Ogawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA