Umbilical cord plasma-derived exosomes from preeclamptic women induce vascular dysfunction by targeting HMGCS1 in endothelial cells

Sexual Dimorphisms of Preeclampsia-Dysregulated Transcriptomic Profiles and Cell Function in Fetal Endothelial Cells

(2019) Chi Zhou et al.   HYPERTENSION

Exosomal microRNA profiling in early and late onset preeclamptic pregnant women reflects pathophysiology

(2019) Preenan Pillay et al.   International Journal of Nanomedicine

Dipyridamole Enhances the Cytotoxicities of the Trametinib Against Colon Cancer Cells Through Combined Targeting HMGCS1 and MEK Pathway

(2019) Sheng Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of HIF-1a-mediated TLR4 activation decreases apoptosis and promotes angiogenesis of placental microvascular endothelial cells during severe pre-eclampsia pathogenesis

(2019) Lina Zhao et al.   PLACENTA

Maternal and umbilical cord serum–derived exosomes enhance endothelial cell proliferation and migration

(2018) Linyan Jia et al.   FASEB JOURNAL

Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia

(2018) Delia I. Chiarello et al.   MOLECULAR ASPECTS OF MEDICINE

Exosomes From Women With Preeclampsia Induced Vascular Dysfunction by Delivering sFlt (Soluble Fms-Like Tyrosine Kinase)-1 and sEng (Soluble Endoglin) to Endothelial Cells

(2018) Xinwen Chang et al.   HYPERTENSION

Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young AdulthoodNovelty and Significance

(2017) Ingvild V. Alsnes et al.   HYPERTENSION

HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600Ein human cancers

(2017) Liang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Placental Exosomes as Early Biomarker of Preeclampsia: Potential Role of Exosomal MicroRNAs Across Gestation

(2017) Carlos Salomon et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Developmental origins of cardiovascular disease: Impact of early life stress in humans and rodents

(2017) M.O. Murphy et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Neurological function in children born to preeclamptic and hypertensive mothers – A systematic review

(2017) Ernesto A. Figueiró-Filho et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Perinatal outcome in singleton pregnancies complicated with preeclampsia and eclampsia in Ecuador

(2016) K.Y.N. Phoa et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Pre-eclampsia

(2016) Ben W J Mol et al.   LANCET

Hypertensive disorders of pregnancy and adult offspring cardiometabolic outcomes: a systematic review of the literature and meta-analysis

(2015) Janine Claire Thoulass et al.   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

Placenta-Derived Exosomes and Syncytiotrophoblast Microparticles and their Role in Human Reproduction: Immune Modulation for Pregnancy Success

(2014) Lucia Mincheva-Nilsson et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Mutation of 3-Hydroxy-3-Methylglutaryl CoA Synthase I Reveals Requirements for Isoprenoid and Cholesterol Synthesis in Oligodendrocyte Migration Arrest, Axon Wrapping, and Myelin Gene Expression

(2014) E. S. Mathews et al.   JOURNAL OF NEUROSCIENCE

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Trophoblast debris extruded from preeclamptic placentae activates endothelial cells: A mechanism by which the placenta communicates with the maternal endothelium

(2014) F. Shen et al.   PLACENTA

Microvesicles of Women With Gestational Hypertension and Preeclampsia Affect Human Trophoblast Fate and Endothelial Function

(2013) Einat Shomer et al.   HYPERTENSION

Preeclampsia, a Disease of the Maternal Endothelium

(2011) Camille E. Powe et al.   CIRCULATION

Molecular Characterization of EG-VEGF-mediated Angiogenesis: Differential Effects on Microvascular and Macrovascular Endothelial Cells

(2010) Sophie Brouillet et al.   MOLECULAR BIOLOGY OF THE CELL