Nociceptin/orphanin FQ neurons in the Arcuate Nucleus and Ventral Tegmental Area Act via Nociceptin Opioid Peptide Receptor Signaling to Inhibit Proopiomelanocortin and A10 Dopamine Neurons and Thereby Modulate Ingestion of Palatable Food

Pituitary Adenylate Cyclase Activating Polypeptide Excites Proopiomelanocortin Neurons: Implications for the Regulation of Energy Homeostasis

(2020) Rachel Chang et al.   NEUROENDOCRINOLOGY

PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding

(2020) Alexander Jais et al.   NEURON

Sex Differences in Demand for Highly Palatable Foods: Role of the Orexin System

(2020) Linnea R Freeman et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Dopamine drives binge‐like consumption of a palatable food in experimental Parkinsonism

(2019) Désirée Mineo et al.   MOVEMENT DISORDERS

Central Amygdala Prepronociceptin-Expressing Neurons Mediate Palatable Food Consumption and Reward

(2019) J. Andrew Hardaway et al.   NEURON

A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia

(2019) Na Qu et al.   MOLECULAR PSYCHIATRY

Sex differences in disordered eating and food addiction among college students

(2018) Zhiping Yu et al.   APPETITE

Reward-representing D1-type neurons in the medial shell of the accumbens nucleus regulate palatable food intake

(2018) Máté Durst et al.   INTERNATIONAL JOURNAL OF OBESITY

Pituitary adenylate cyclase-activating polypeptide (PACAP) acts in the nucleus accumbens to reduce hedonic drive

(2018) Matthew M. Hurley et al.   INTERNATIONAL JOURNAL OF OBESITY

Acute effects of zinc and insulin on arcuate anorexigenic proopiomelanocortin neurons

(2018) Zhenyan He et al.   BRITISH JOURNAL OF PHARMACOLOGY

The dopamine motive system: implications for drug and food addiction

(2017) Nora D. Volkow et al.   NATURE REVIEWS NEUROSCIENCE

Estradiol is a critical regulator of food-reward behavior

(2017) Jennifer E. Richard et al.   PSYCHONEUROENDOCRINOLOGY

Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis

(2016) Virginia Mela et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling

(2016) Kristie Conde et al.   NEUROENDOCRINOLOGY

Testosterone Rapidly Augments Retrograde Endocannabinoid Signaling in Proopiomelanocortin Neurons to Suppress Glutamatergic Input from Steroidogenic Factor 1 Neurons via Upregulation of Diacylglycerol Lipase-α

(2016) Kristie Conde et al.   NEUROENDOCRINOLOGY

Removal of high-fat diet after chronic exposure drives binge behavior and dopaminergic dysregulation in female mice

(2016) Jesse L. Carlin et al.   NEUROSCIENCE

Food addiction symptomology, impulsivity, mood, and body mass index in people with type two diabetes

(2015) Karren-Lee Raymond et al.   APPETITE

Palatability Can Drive Feeding Independent of AgRP Neurons

(2015) Raphaël G.P. Denis et al.   Cell Metabolism

Binge eating in pre-clinical models

(2015) Bartłomiej Rospond et al.   Pharmacological Reports

Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling

(2015) Spring Valdivia et al.   PSYCHONEUROENDOCRINOLOGY

Bidirectional relationship between the body mass index and substance use in young men

(2015) Alexandra A. N'Goran et al.   Substance Abuse

Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

(2014) Jian Qiu et al.   Cell Metabolism

An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger

(2014) Michael J. Krashes et al.   NATURE

CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin

(2014) Pierre Cardinal et al.   Molecular Metabolism

Conditional viral tracing reveals that steroidogenic factor 1-positive neurons of the dorsomedial subdivision of the ventromedial hypothalamus project to autonomic centers of the hypothalamus and hindbrain

(2013) Daniel Lindberg et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Estradiol Negatively Modulates the Pleiotropic Actions of Orphanin FQ/Nociceptin at Proopiomelanocortin Synapses

(2013) Amanda Borgquist et al.   NEUROENDOCRINOLOGY

Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning

(2012) Matthew T. C. Brown et al.   NATURE

The neurobiology of food intake in an obesogenic environment

(2012) Hans-Rudolf Berthoud   PROCEEDINGS OF THE NUTRITION SOCIETY

Nociceptin/orphanin FQ suppresses the excitability of neurons in the ventromedial nucleus of the hypothalamus

(2011) Melissa J. Chee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

(2011) Joanna Mattis et al.   NATURE METHODS

High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons

(2011) Tim Klöckener et al.   NATURE NEUROSCIENCE

Dysregulation of brain reward systems in eating disorders: Neurochemical information from animal models of binge eating, bulimia nervosa, and anorexia nervosa

(2011) Nicole M. Avena et al.   NEUROPHARMACOLOGY

Eating behavior in obese and overweight persons with and without anhedonia

(2010) Anna-Maria Keränen et al.   APPETITE

Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels

(2010) J. Qiu et al.   JOURNAL OF NEUROSCIENCE

The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons

(2010) Borzoo Farhang et al.   NEUROPHARMACOLOGY

The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation

(2009) V Di Marzo et al.   INTERNATIONAL JOURNAL OF OBESITY

Steroidogenic Factor 1 Regulates Expression of the Cannabinoid Receptor 1 in the Ventromedial Hypothalamic Nucleus

(2008) Ki Woo Kim et al.   MOLECULAR ENDOCRINOLOGY

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

The incentive sensitization theory of addiction: some current issues

(2008) T. E Robinson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES