Reconstitution of mammalian mitochondrial translation system capable of correct initiation and long polypeptide synthesis from leaderless mRNA

Reconstitution of yeast translation elongation and termination in vitro utilizing CrPV IRES-containing mRNA

(2020) Taisho Abe et al.   JOURNAL OF BIOCHEMISTRY

In vitro yeast reconstituted translation system reveals function of eIF5A for synthesis of long polypeptide

(2020) Taisho Abe et al.   JOURNAL OF BIOCHEMISTRY

Structural insights into mammalian mitochondrial translation elongation catalyzed by mt EFG 1

(2020) Eva Kummer et al.   EMBO JOURNAL

Distinct pre-initiation steps in human mitochondrial translation

(2020) Anas Khawaja et al.   Nature Communications

Structural basis of mitochondrial translation

(2020) Shintaro Aibara et al.   eLife

Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome

(2019) Nurun Nahar Borna et al.   NEUROGENETICS

The Origin and Evolution of Release Factors: Implications for Translation Termination, Ribosome Rescue, and Quality Control Pathways

(2019) A. Maxwell Burroughs et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM

(2018) Eva Kummer et al.   NATURE

Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing

(2017) Yuhei Chadani et al.   MOLECULAR CELL

eIF5A Functions Globally in Translation Elongation and Termination

(2017) Anthony P. Schuller et al.   MOLECULAR CELL

LRPPRC-mediated folding of the mitochondrial transcriptome

(2017) Stefan J. Siira et al.   Nature Communications

Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein

(2016) Ricarda Richter-Dennerlein et al.   CELL

Human mitochondrial ribosomes can switch their structural RNA composition

(2016) Joanna Rorbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial transcript maturation and its disorders

(2015) Lindsey Van Haute et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

The structure of the human mitochondrial ribosome

(2015) A. Amunts et al.   SCIENCE

Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography

(2015) Stefan Pfeffer et al.   Nature Communications

MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation

(2014) Xiaorong Zhang et al.   CELL

Making Proteins in the Powerhouse

(2014) B. Martin Hällberg et al.   Cell Metabolism

The complete structure of the large subunit of the mammalian mitochondrial ribosome

(2014) Basil J. Greber et al.   NATURE

Cryo-EM structure of the small subunit of the mammalian mitochondrial ribosome

(2014) P. S. Kaushal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the large ribosomal subunit from human mitochondria

(2014) A. Brown et al.   SCIENCE

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

(2014) Shiori Akabane et al.   PLoS Genetics

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

Architecture of the large subunit of the mammalian mitochondrial ribosome

(2013) Basil J. Greber et al.   NATURE

Mitochondrial Protein Synthesis, Import, and Assembly

(2012) Thomas D. Fox   GENETICS

EF-P Is Essential for Rapid Synthesis of Proteins Containing Consecutive Proline Residues

(2012) L. K. Doerfel et al.   SCIENCE

Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches

(2012) S. Ude et al.   SCIENCE

Human Mitochondrial tRNAs: Biogenesis, Function, Structural Aspects, and Diseases

(2011) Tsutomu Suzuki et al.   Annual Review of Genetics

Mechanism of protein biosynthesis in mammalian mitochondria

(2011) Brooke E. Christian et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1

(2011) A. S. Yassin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the functional consequences of lethal mutations in mitochondrial translational elongation factors

(2010) Kenta Akama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Preferential Selection of the 5′-Terminal Start Codon on Leaderless mRNAs by Mammalian Mitochondrial Ribosomes

(2010) Brooke E. Christian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for an Active Role of IF3mtin the Initiation of Translation in Mammalian Mitochondria†

(2009) Brooke E. Christian et al.   BIOCHEMISTRY

Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation

(2009) Stefan M.K. Davies et al.   FEBS LETTERS

EF-G2mt Is an Exclusive Recycling Factor in Mammalian Mitochondrial Protein Synthesis

(2009) Masafumi Tsuboi et al.   MOLECULAR CELL

Unconventional decoding of the AUA codon as methionine by mitochondrial tRNA Met with the anticodon f 5 CAU as revealed with a mitochondrial in vitro translation system

(2009) Chie Takemoto et al.   NUCLEIC ACIDS RESEARCH

Distinct functions of elongation factor G in ribosome recycling and translocation

(2009) A. Savelsbergh et al.   RNA

The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State

(2009) Y.-G. Gao et al.   SCIENCE

A Single Mammalian Mitochondrial Translation Initiation Factor Functionally Replaces Two Bacterial Factors

(2008) Rahul Gaur et al.   MOLECULAR CELL