Can the interplay between autophagy and apoptosis be targeted as a novel therapy for Parkinson's disease?

Progress in the genetic analysis of Parkinson’s disease

(2019) Andrew Singleton et al.   HUMAN MOLECULAR GENETICS

Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models

(2018) Jia Liu et al.   Autophagy

Curcumin: A naturally occurring autophagy modulator

(2018) Abolfazl Shakeri et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Balancing apoptosis and autophagy for Parkinson’s disease therapy: targeting BCL-2

(2018) Jia Liu et al.   ACS Chemical Neuroscience

Dysregulated autophagy contributes to caspase-dependent neuronal apoptosis

(2018) Yuhyun Chung et al.   Cell Death & Disease

Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress

(2017) Shuling Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2017) Valery L Feigin et al.   LANCET NEUROLOGY

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

(2017) Fiona M. Menzies et al.   NEURON

Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice

(2016) Chuang Guo et al.   EXPERIMENTAL NEUROLOGY

Curcumin Rescues a PINK1 Knock Down SH-SY5Y Cellular Model of Parkinson’s Disease from Mitochondrial Dysfunction and Cell Death

(2016) Celia van der Merwe et al.   MOLECULAR NEUROBIOLOGY

Anti-apoptotic effect of modified Chunsimyeolda-tang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model

(2015) Huan Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cell Death Signaling

(2015) Douglas R. Green et al.   Cold Spring Harbor Perspectives in Biology

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

(2015) Xue Yang et al.   Cell and Bioscience

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation

(2014) Yongjie Wei et al.   Autophagy

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Rutin from Dendropanax morbifera Leveille Protects Human Dopaminergic Cells Against Rotenone Induced Cell Injury Through Inhibiting JNK and p38 MAPK Signaling

(2014) Se-Eun Park et al.   NEUROCHEMICAL RESEARCH

Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex

(2014) Haroon Badshah et al.   NEUROCHEMISTRY INTERNATIONAL

Gastrodin protects against MPP+-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells

(2014) Genling Jiang et al.   NEUROCHEMISTRY INTERNATIONAL

The Role of Intrinsic Pathway in Apoptosis Activation and Progression in Peyronie’s Disease

(2014) Carla Loreto et al.   Biomed Research International

The variability of autophagy and cell death susceptibility

(2013) Ben Loos et al.   Autophagy

Adaptation to metabolic stress: Insights into a paradoxical Q

(2013) Michael A. Reid et al.   CELL CYCLE

Curcumin Ameliorates the Neurodegenerative Pathology in A53T α-synuclein Cell Model of Parkinson’s Disease Through the Downregulation of mTOR/p70S6K Signaling and the Recovery of Macroautophagy

(2013) Tian-Fang Jiang et al.   Journal of Neuroimmune Pharmacology

Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells

(2013) Anja Hafner Pišlar et al.   NEUROPHARMACOLOGY

Autophagy and apoptosis dysfunction in neurodegenerative disorders

(2013) Saeid Ghavami et al.   PROGRESS IN NEUROBIOLOGY

Role of the Crosstalk between Autophagy and Apoptosis in Cancer

(2013) Minfei Su et al.   Journal of Oncology

Isoliquiritigenin Isolated from LicoriceGlycyrrhiza uralensisPrevents 6-Hydroxydopamine-Induced Apoptosis in Dopaminergic Neurons

(2012) Cheol Kyu HWANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Non-apoptotic functions of apoptosis-regulatory proteins

(2012) Lorenzo Galluzzi et al.   EMBO REPORTS

Astragaloside IV prevents MPP+-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production

(2012) Zhi-guo Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Autophagy and Neuronal Cell Death in Neurological Disorders

(2012) R. A. Nixon et al.   Cold Spring Harbor Perspectives in Biology

Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson’s disease through suppressing mitochondria dysfunction

(2012) Jing Pan et al.   Translational Neurodegeneration

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Autophagy failure in Alzheimer's disease—locating the primary defect

(2011) Ralph A. Nixon et al.   NEUROBIOLOGY OF DISEASE

Standardized Extracts of Bacopa monniera Protect Against MPP+- and Paraquat-Induced Toxicity by Modulating Mitochondrial Activities, Proteasomal Functions, and Redox Pathways

(2011) Manjeet Singh et al.   TOXICOLOGICAL SCIENCES

Autophagy and apoptosis: what is the connection?

(2011) Jacob M. Gump et al.   TRENDS IN CELL BIOLOGY

Detoxified Extract of Rhus verniciflua Stokes Inhibits Rotenone-Induced Apoptosis in Human Dopaminergic Cells, SH-SY5Y

(2010) Kumar Sapkota et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclo(His-Pro) up-regulates heme oxygenase 1 via activation of Nrf2-ARE signalling

(2009) Alba Minelli et al.   JOURNAL OF NEUROCHEMISTRY

p53 Regulation of the IGF-1/AKT/mTOR Pathways and the Endosomal Compartment

(2009) Z. Feng   Cold Spring Harbor Perspectives in Biology

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE