Molecular basis for arginine C-terminal degron recognition by Cul2FEM1 E3 ligase

Tying up loose ends: the N-degron and C-degron pathways of protein degradation

(2020) Richard T. Timms et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phase separation drives decision making in cell division

(2020) Xing Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-degron and C-degron pathways of protein degradation

(2019) Alexander Varshavsky   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic variation across the human olfactory receptor repertoire alters odor perception

(2019) C. Trimmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into SETD3-mediated histidine methylation on β-actin

(2019) Qiong Guo et al.   eLife

Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases

(2019) Matthew Ravalin et al.   Nature Chemical Biology

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

(2019) Richard T. Timms et al.   SCIENCE

The protein complex crystallography beamline (BL19U1) at the Shanghai Synchrotron Radiation Facility

(2019) Wei-Zhe Zhang et al.   Nuclear Science and Techniques

The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons

(2018) Itay Koren et al.   CELL

At Long Last, a C-Terminal Bookend for the Ubiquitin Code

(2018) Andrew Chatr-aryamontri et al.   MOLECULAR CELL

C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases

(2018) Hsiu-Chuan Lin et al.   MOLECULAR CELL

Upgrade of macromolecular crystallography beamline BL17U1 at SSRF

(2018) Qi-Sheng Wang et al.   Nuclear Science and Techniques

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

(2018) Sang-Min Jang et al.   Nature Communications

Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter

(2018) Do Hoon Kwon et al.   Nature Communications

Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase

(2018) Domniţa-Valeria Rusnac et al.   MOLECULAR CELL

ZZ-dependent regulation of p62/SQSTM1 in autophagy

(2018) Yi Zhang et al.   Nature Communications

Ubiquitylation at the crossroads of development and disease

(2017) Michael Rape   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An N-end rule pathway that recognizes proline and destroys gluconeogenic enzymes

(2017) Shun-Jia Chen et al.   SCIENCE

Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8

(2015) Jianyun Nie et al.   STRUCTURE

Structural basis of diverse membrane target recognitions by ankyrins

(2014) Chao Wang et al.   eLife

Cullin-RING Ligases as Attractive Anti-cancer Targets

(2013) Yongchao Zhao et al.   CURRENT PHARMACEUTICAL DESIGN

The N-End Rule Pathway

(2012) Takafumi Tasaki et al.   Annual Review of Biochemistry

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

(2012) A. Dey et al.   SCIENCE

Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock

(2012) C. Xu et al.   Science Signaling

Recent advances in theCRANKsoftware suite for experimental phasing

(2011) Navraj S. Pannu et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The N-end rule pathway: From recognition by N-recognins, to destruction by AAA+proteases

(2011) D.A. Dougan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Global Identification of Modular Cullin-RING Ligase Substrates

(2011) Michael J. Emanuele et al.   CELL

The cullin protein family

(2011) Antonio Sarikas et al.   GENOME BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

RACK1 down-regulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells

(2010) M. Cecilia Subauste et al.   CANCER BIOLOGY & THERAPY

Structural basis for methylarginine-dependent recognition of Aubergine by Tudor

(2010) H. Liu et al.   GENES & DEVELOPMENT

Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain

(2010) K. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-Associated Mutant Ubiquitin Causes Proteasomal Impairment and Enhances the Toxicity of Protein Aggregates

(2009) Elizabeth M. H. Tank et al.   PLoS Genetics

Characterization of Cullin-box Sequences That Direct Recruitment of Cul2-Rbx1 and Cul5-Rbx2 Modules to Elongin BC-based Ubiquitin Ligases

(2008) Nawel Mahrour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Substrate Recognition Domains of the N-end Rule Pathway

(2008) Takafumi Tasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

(2008) Robert E Collins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE

Cullin-RING ubiquitin ligases: global regulation and activation cycles

(2008) Dimple R Bosu et al.   Cell Division