Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

(2019) Rebecca M. Marton et al.   NATURE NEUROSCIENCE

Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia

(2019) Johannes Klaus et al.   NATURE MEDICINE

Specification of positional identity in forebrain organoids

(2019) Gustav Y. Cederquist et al.   NATURE BIOTECHNOLOGY

Human 3D cellular model of hypoxic brain injury of prematurity

(2019) Anca M. Pașca et al.   NATURE MEDICINE

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Atypical behaviour and connectivity in SHANK3-mutant macaques

(2019) Yang Zhou et al.   NATURE

Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B Mice

(2019) Rui Tiago Peixoto et al.   Cell Reports

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Genetic Dissection of Neural Circuits: A Decade of Progress

(2018) Liqun Luo et al.   NEURON

Genetically engineered human cortical spheroid models of tuberous sclerosis

(2018) John D. Blair et al.   NATURE MEDICINE

Generation and assembly of human brain region–specific three-dimensional cultures

(2018) Steven A. Sloan et al.   Nature Protocols

Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period

(2018) Ori J. Lieberman et al.   NEURON

Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents

(2018) Kazuki Tainaka et al.   Cell Reports

Efficient scarless genome editing in human pluripotent stem cells

(2018) Kazuya Ikeda et al.   NATURE METHODS

Reliability of human cortical organoid generation

(2018) Se-Jin Yoon et al.   NATURE METHODS

Building Models of Brain Disorders with Three-Dimensional Organoids

(2018) Neal D. Amin et al.   NEURON

Assembly of functionally integrated human forebrain spheroids

(2017) Fikri Birey et al.   NATURE

Bidirectional Control of Generalized Epilepsy Networks via Rapid Real-Time Switching of Firing Mode

(2017) Jordan M. Sorokin et al.   NEURON

Regulation of Thalamic and Cortical Network Synchrony by Scn8a

(2017) Christopher D. Makinson et al.   NEURON

Two-photon imaging in mice shows striosomes and matrix have overlapping but differential reinforcement-related responses

(2017) Bernard Bloem et al.   eLife

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B−/− mice

(2016) Rui T Peixoto et al.   NATURE NEUROSCIENCE

A viral strategy for targeting and manipulating interneurons across vertebrate species

(2016) Jordane Dimidschstein et al.   NATURE NEUROSCIENCE

Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate

(2016) Shanni N. Silberberg et al.   NEURON

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons

(2016) F. Yi et al.   SCIENCE

rAAV-compatible MiniPromoters for restricted expression in the brain and eye

(2016) Charles N. de Leeuw et al.   Molecular Brain

Activin A directs striatal projection neuron differentiation of human pluripotent stem cells

(2015) C. Arber et al.   DEVELOPMENT

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

(2015) Anca M Paşca et al.   NATURE METHODS

Single-cell-initiated monosynaptic tracing reveals layer-specific cortical network modules

(2015) A. Wertz et al.   SCIENCE

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Molecular and functional definition of the developing human striatum

(2014) Marco Onorati et al.   NATURE NEUROSCIENCE

Transneuronal propagation of mutant huntingtin contributes to non–cell autonomous pathology in neurons

(2014) Eline Pecho-Vrieseling et al.   NATURE NEUROSCIENCE

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

(2014) Thomas J Cradick et al.   Molecular Therapy-Nucleic Acids

Cytosystems dynamics in self-organization of tissue architecture

(2013) Yoshiki Sasai   NATURE

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

(2013) Aleksandr Shcheglovitov et al.   NATURE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Corticostriatal connectivity and its role in disease

(2013) Gordon M. G. Shepherd   NATURE REVIEWS NEUROSCIENCE

Human Embryonic Stem Cell-Derived GABA Neurons Correct Locomotion Deficits in Quinolinic Acid-Lesioned Mice

(2012) Lixiang Ma et al.   Cell Stem Cell

Anatomic and Molecular Development of Corticostriatal Projection Neurons in Mice

(2012) U. Shivraj Sohur et al.   CEREBRAL CORTEX

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

(2012) A. D. Carri et al.   DEVELOPMENT

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Modeling human cortical development in vitro using induced pluripotent stem cells

(2012) J. Mariani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A translocation between Xq21.33 and 22q13.33 causes an intragenic SHANK3 deletion in a woman with Phelan-McDermid syndrome and hypergonadotropic hypogonadism

(2011) D. Misceo et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Effects of NR2A and NR2B-containing N-methyl-D-aspartate receptors on neuronal-firing properties

(2011) Meimei Shi et al.   NEUROREPORT

Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways

(2011) Mohammed R. Milad et al.   TRENDS IN COGNITIVE SCIENCES

Developmental Origin of the Neuronal Subtypes That Comprise the Amygdalar Fear Circuit in the Mouse

(2010) R. R. Waclaw et al.   JOURNAL OF NEUROSCIENCE

Cation-Chloride Cotransporters and Neuronal Function

(2009) Peter Blaesse et al.   NEURON

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell