Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

(2015) Sara M. Atkinson et al.   AUTOIMMUNITY

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

Kinetics of gene expression and bone remodelling in the clinical phase of collagen-induced arthritis

(2015) Katja CM Denninger et al.   ARTHRITIS RESEARCH & THERAPY

Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli

(2015) Jacob Bak Holm et al.   PLoS One

Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options

(2014) Natasja S. Gudmann et al.   AUTOIMMUNITY

Th17 and regulatory T cell balance in autoimmune and inflammatory diseases

(2014) Mélissa Noack et al.   AUTOIMMUNITY REVIEWS

T cell subsets and their role in the pathogenesis of rheumatic disease

(2014) Alison M. Gizinski et al.   CURRENT OPINION IN RHEUMATOLOGY

IL-6 Regulates Neutrophil Trafficking during Acute Inflammation via STAT3

(2014) C. A. Fielding et al.   JOURNAL OF IMMUNOLOGY

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

TREG-cell therapies for autoimmune rheumatic diseases

(2014) Makoto Miyara et al.   Nature Reviews Rheumatology

Amelioration of experimental arthritis by stroke-induced immunosuppression is independent of Tregcell function

(2013) Ingo M Irmler et al.   ANNALS OF THE RHEUMATIC DISEASES

Chronic low dose tumor necrosis factor-α (TNF) suppresses early bone accrual in young mice by inhibiting osteoblasts without affecting osteoclasts

(2013) L.C. Gilbert et al.   BONE

Analysis of Fecal Lactobacillus Community Structure in Patients with Early Rheumatoid Arthritis

(2013) Xiaofei Liu et al.   CURRENT MICROBIOLOGY

Differential abundance analysis for microbial marker-gene surveys

(2013) Joseph N Paulson et al.   NATURE METHODS

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

(2013) Paul J. McMurdie et al.   PLoS One

Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics

(2013) Wim B. van den Berg et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Suppression of inflammation and effects on new bone formation in ankylosing spondylitis: evidence for a window of opportunity in disease modification

(2012) Walter P Maksymowych et al.   ANNALS OF THE RHEUMATIC DISEASES

Reciprocal interactions of the intestinal microbiota and immune system

(2012) Craig L. Maynard et al.   NATURE

Bone Formation and Resorption Are Both Increased in Experimental Autoimmune Arthritis

(2012) Kresten Krarup Keller et al.   PLoS One

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

(2012) Katelin R Haynes et al.   ARTHRITIS RESEARCH & THERAPY

Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice

(2012) Sara M Atkinson et al.   ARTHRITIS RESEARCH & THERAPY

Th17 Cells, Not IL-17+    T Cells, Drive Arthritic Bone Destruction in Mice and Humans

(2011) B. Pollinger et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis

(2010) O. Frey et al.   ANNALS OF THE RHEUMATIC DISEASES

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Novel role of regulatory T cells in limiting early neutrophil responses in skin

(2010) Hannah Richards et al.   IMMUNOLOGY

Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis

(2010) M. M. Zaiss et al.   JOURNAL OF IMMUNOLOGY

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Tumor necrosis factor α and RANKL blockade cannot halt bony spur formation in experimental inflammatory arthritis

(2009) Georg Schett et al.   ARTHRITIS AND RHEUMATISM

Animal models of rheumatoid arthritis

(2009) Darren L. Asquith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

(2009) Markus Feuerer et al.   IMMUNITY

IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-α antibody: A novel mechanism of osteoclastogenesis by IL-17

(2009) Toru Yago et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Collagen antibody-induced arthritis in mice: Development of a new arthritogenic 5-clone cocktail of monoclonal anti-type II collagen antibodies

(2009) Pilaiwanwadee Hutamekalin et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Activated CD4+CD25+ regulatory T cells inhibit osteoclastogenesis and collagen-induced arthritis

(2008) H Kelchtermans et al.   ANNALS OF THE RHEUMATIC DISEASES

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION

GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival

(2008) Ivo Sonderegger et al.   JOURNAL OF EXPERIMENTAL MEDICINE