Lysine demethylase 5B suppresses CC chemokine ligand 14 to promote progression of colorectal cancer through the Wnt/β-catenin pathway

CCL14 is a prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma

(2020) Yurong Gu et al.   Aging-US

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B)

(2020) Bing Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

KDM5B-mediated microRNA-448 up-regulation restrains papillary thyroid cancer cell progression and slows down tumor growth via TGIF1 repression

(2020) Ying Pu et al.   LIFE SCIENCES

Targeting cancer stem cells as therapeutic approach in the treatment of colorectal cancer

(2019) Seyed Mostafa Parizadeh et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

KDM5B promotes breast cancer cell proliferation and migration via AMPK-mediated lipid metabolism reprogramming

(2019) Zhong-Guo Zhang et al.   EXPERIMENTAL CELL RESEARCH

Regorafenib Prior to Selective Internal Radiation Therapy Using 90Y-Resin Microspheres for Refractory Metastatic Colorectal Cancer Liver Metastases: Analysis of Safety, Dosimetry, and Molecular Markers

(2019) Andrew Kennedy et al.   Frontiers in Oncology

ACLY facilitates colon cancer cell metastasis by CTNNB1

(2019) Jun Wen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

CCL14 serves as a novel prognostic factor and tumor suppressor of HCC by modulating cell cycle and promoting apoptosis

(2019) Mengxuan Zhu et al.   Cell Death & Disease

Epigenetic and epitranscriptomic changes in colorectal cancer: Diagnostic, prognostic, and treatment implications

(2018) Elisa Porcellini et al.   CANCER LETTERS

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors

(2018) Nithya Krishnamurthy et al.   CANCER TREATMENT REVIEWS

The role of epigenetic therapies in colorectal cancer

(2018) Marina Baretti et al.   CURRENT PROBLEMS IN CANCER

Nivolumab for the treatment of colorectal cancer

(2018) Kortnye Maureen Smith et al.   Expert Review of Anticancer Therapy

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Lysine demethylase 5B (KDM5B): A potential anti-cancer drug target

(2018) Yi-Chao Zheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer

(2018) Besa Xhabija et al.   SEMINARS IN CANCER BIOLOGY

Increased Expression of Lysine-Specific Demethylase 5B (KDM5B) Promotes Tumor Cell Growth in Hep3B Cells and is an Independent Prognostic Factor in Patients with Hepatocellular Carcinoma

(2018) Jian Gong et al.   MEDICAL SCIENCE MONITOR

Therapeutic potential of targeting the Wnt/β-catenin signaling pathway in colorectal cancer

(2018) Xiaofei Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancers

(2016) Ching-Yu Yen et al.   CANCER LETTERS

Targeting histone lysine methylation in cancer

(2015) John McGrath et al.   PHARMACOLOGY & THERAPEUTICS

Depletion of JARID1B induces cellular senescence in human colorectal cancer

(2013) KATSUYA OHTA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Binding of the JmjC Demethylase JARID1B to LSD1/NuRD Suppresses Angiogenesis and Metastasis in Breast Cancer Cells by Repressing Chemokine CCL14

(2011) Q. Li et al.   CANCER RESEARCH