4.5 Article

Refinement of spectra using a deep neural network: Fully automated removal of noise and background

期刊

JOURNAL OF RAMAN SPECTROSCOPY
卷 52, 期 3, 页码 723-736

出版社

WILEY
DOI: 10.1002/jrs.6053

关键词

deep learning; fluorescence rejection; noise reduction; Raman spectra; U-Net

资金

  1. Wilhelm Sander-Stiftung [2017.111.1, 2017.111.2]
  2. European Union's Horizon 2020 research and innovation program [637654]
  3. European Research Council (ERC) [637654] Funding Source: European Research Council (ERC)

向作者/读者索取更多资源

The study demonstrates the potential of the U-Net deep neural network for efficient noise and background removal in Raman spectra. Test results show high structural similarity index for recovered Raman spectra features.
We report the potential of U-Net deep neural network for the efficient removal of noise and background from raw Raman spectra. The U-Net method was first trained on simulated spectra and then tested with experimental spectra. The quality of the test results was quantified via different signal-to-noise ratios and the structural similarity index metric. The U-Net recovered Raman spectra feature a high structural similarity index, even for raw spectra that were dominated by background. The U-Net model does not rely on any human intervention.

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