Efficient whole brain transduction by systemic infusion of minimally purified AAV-PHP.eB

The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier

(2019) Juliette Hordeaux et al.   MOLECULAR THERAPY

The blood-brain barrier: Physiology and strategies for drug delivery

(2019) Rucha Pandit et al.   ADVANCED DRUG DELIVERY REVIEWS

Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids

(2019) Qin Huang et al.   PLoS One

Recent progress and considerations for AAV gene therapies targeting the central nervous system

(2018) Erik Allen Lykken et al.   Journal of Neurodevelopmental Disorders

Elavl3 is essential for the maintenance of Purkinje neuron axons

(2018) Yuki Ogawa et al.   Scientific Reports

Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes

(2018) Shelley A. Nass et al.   Molecular Therapy-Methods & Clinical Development

Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System

(2018) Yoichiro Shinohara et al.   MOLECULAR NEUROBIOLOGY

Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology

(2018) Masashi Watanave et al.   NEUROBIOLOGY OF DISEASE

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

Host determinants of adeno-associated viral vector entry

(2017) Sirika Pillay et al.   Current Opinion in Virology

Persistent Expression of Dopamine-Synthesizing Enzymes 15 Years After Gene Transfer in a Primate Model of Parkinson's Disease

(2017) Yoshihide Sehara et al.   Human Gene Therapy Clinical Development

Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells

(2016) Steven F. Merkel et al.   JOURNAL OF NEUROCHEMISTRY

An essential receptor for adeno-associated virus infection

(2016) S. Pillay et al.   NATURE

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

(2016) Benjamin E Deverman et al.   NATURE BIOTECHNOLOGY

Parvovirus glycan interactions

(2014) Lin-Ya Huang et al.   Current Opinion in Virology

A simplified purification protocol for recombinant adeno-associated virus vectors

(2014) Mark Potter et al.   Molecular Therapy-Methods & Clinical Development

Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model

(2014) Fathul Huda et al.   Molecular Therapy-Methods & Clinical Development

Rapid and simplified purification of recombinant adeno-associated virus

(2012) Ping Guo et al.   JOURNAL OF VIROLOGICAL METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A simplified purification method for AAV variant by polyethylene glycol aqueous two-phase partitioning

(2012) Ping Guo et al.   Bioengineered

Adeno-Associated Virus (AAV) Vectors in the CNS

(2011) Thomas J. McCown   CURRENT GENE THERAPY

Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman Primates

(2011) Steven J Gray et al.   MOLECULAR THERAPY

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

(2009) E Ayuso et al.   GENE THERAPY