Microglial TonEBP mediates LPS-induced inflammation and memory loss as transcriptional cofactor for NF-κB and AP-1

The evolving role of TonEBP as an immunometabolic stress protein

(2020) Soo Youn Choi et al.   Nature Reviews Nephrology

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

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Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities

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Tonicity-responsive enhancer-binding protein promotes hepatocellular carcinogenesis, recurrence and metastasis

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The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages

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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis

(2017) Marta Pulido-Salgado et al.   Journal of Neuroinflammation

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Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microglia

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TonEBP suppresses IL-10-mediated immunomodulation

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LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding

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Innate Immune Response in Brain, NF-Kappa B Signaling and Cystatins

(2015) Nataša Kopitar-Jerala   Frontiers in Molecular Neuroscience

The common inflammatory etiology of depression and cognitive impairment: a therapeutic target

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Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis

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Microglia-derived TNFα induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma

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Sinomenine inhibits microglial activation by Aβ and confers neuroprotection

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Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

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Associative Learning and CA3-CA1 Synaptic Plasticity Are Impaired in D1R Null, Drd1a-/- Mice and in Hippocampal siRNA Silenced Drd1a Mice

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Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds

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The role of microglia in central nervous system immunity and glioma immunology

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Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

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Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress

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The anti-amnesic and neuroprotective effects of donepezil against amyloid β25-35 peptide-induced toxicity in mice involve an interaction with the σ1 receptor

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